Pharmacology Quiz 1

Front 1

Drug

Back 1

Chemical capable of producing a biological effect

Front 2

Pharmacology

Back 2

The study of mechanisms of drug action

Front 3

Pharmacokinetics

Back 3

What does the body do with the drug?

Absorption
Distribution
Metabolism
Excretion

Front 4

Pharmacodynamics

Back 4

What does the drug do to the body?

Front 5

Toxicology

Back 5

The study of poisons and harmful effects of drugs

Front 6

Therapeutics

Back 6

Treating disease with drugs

Front 7

Pharmacy

Back 7

Preparation, dispensing, and use of drugs

Front 8

Pharmacognosy

Back 8

Drug extraction from natural products

Front 9

Pharmaceutics

Back 9

Formulation of drugs

Front 10

Drug Sources

Back 10

Plants (Alkaloids)
Animals (Hormones)
Minterals
Synthetics

Front 11

Tablets/Capsules

Back 11

Active constituents with inert ingredients

Front 12

Enteric Coatings

Back 12

Polymers that will not disintegrate in gastric acid but will break down in the more alkaline intestines

Front 13

Syrup

Back 13

Sweetened aqueous solution

Front 14

Elixir

Back 14

Sweetened aqueous-alcoholic solutions

Front 15

Enteral Administration

Back 15

Oral, Rectal, Buccal, Sublingual

Front 16

Parenteral Administration

Back 16

Intravenous (IV), Intramuscular (IM), Subcutaneous (SC), Intrathecal, Intra-articular

Front 17

Intrathecal Administration

Back 17

Injection of a drug through the theca of the spinal cord into the subarachnoid space

Front 18

Intra-articular Administration

Back 18

Injection of a drug into a joint

Front 19

Chemical Name

Back 19

Specifies the chemical structure of the drug w/standard chemical nomenclature

Front 20

Nonproprietary/Generic Name

Back 20

Determined by the United States Adopted Names Council (USAN). Most appropriate for use in clinical practice.

Front 21

Proprietary/Trade/Brand Name

Back 21

Registered trademark belonging to a particular drug manufacturer and used to designate a drug product marketed by the manufacturer.

Front 22

Primary Routes of Administration

Back 22

Enteral, Parenteral, Transdermal, Inhalational, Topical

Front 23

Routes That Avoid First Pass Hepatic Metabolism

Back 23

Transdermal, Sublingual, Parenteral

Front 24

Weak Acid

Back 24

Chemical that is NOT charged when it is protonated

Only absorbed when protonated

Front 25

Weak Base

Back 25

Chemical that IS charged when it is protonated

Only absorbed when NOT protonated

Front 26

pKa

Back 26

the pH at which equal amounts of drug are charged and uncharged

Front 27

Volume of Distribution (Vd)

Back 27

The volume of fluid in which a drug would need to be dissolved to have the same concentration in that volume as it does in the plasma

Front 28

Cp0

Back 28

Concentration in plasma at time zero

Front 29

Phase I Biotransformation

Back 29

Oxidation, hydrolysis, or reduction

Front 30

Phase II Biotransformation

Back 30

Conjugation

Front 31

Prodrugs

Back 31

Administered as inactive compounds, but become active metabolites after biotransformation

Front 32

Drug Biotransformation

Back 32

Enzymatic metabolism of drugs to terminate the effect of a xenobiotic, or to activate a prodrug

Front 33

Phase I Biotransformation

Back 33

Oxidation, Hydrolysis, Reduction

Front 34

Phase II Biotransformation

Back 34

Conjugation

Front 35

Influences of Drug Biotransformation

Back 35

Genetics, Age, Pathology, Other Drugs

Front 36

3 Phases of Renal Excretion

Back 36

Glomerular Filtration, Active Tubular Secretion, Tubular Re-Absorption

Front 37

Routes of Excretion

Back 37

Renal (most), Biliary (high molecular weights), sweat, saliva

Front 38

First Order Elimination Kinetics

Back 38

Fraction of drug is removed per unit time.

Dependent upon plasma drug concentration.