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58 Cards in this Set
- Front
- Back
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Nitazoxanide Indications?
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diarrhea caused by giardiasis or cryptospyridium parvum in kids
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Nitazoxanide MOA
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Interferes with pyruvate:ferredoxin oxyreductase
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Nitazoxanide is converted to?
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Tizoxanide
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Who uses nitazoxanide?
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Kids cause it tastes better
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Methylprednisolone MOA
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Inhib of prostaglanding synthesis
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SE of sudden glucocorticoid w/drawal
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acute renal insuff, diabetes, osteoporosis, muscle wasting and stunted growth in kids
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5-ASA MOA
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Inhibs leukotriene and PG synthesis, decreases neutrophil chemotaxis
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5-ASA (sulfasalazine)used for?
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Used in UC and Crohn's to cause remission and for long-term tx
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Infliximab MOA
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binds (inhibs) TNF-alpha. Inflicts tnf-alpha
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Quinine MOA
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Unknown
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Quinine MOA
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Schizonticide and Gametocide
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Quinine schizonticide effects which malaria?
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All
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Quinine gametocide effects which malaria?
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vivax and ovale
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quinine contra's
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people w/ auditory/visual disturbs and not w/ mefloquine
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Clyndamycin MOA
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binds 50s and inhibs protien synth
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Clindamycin used for
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strep, staph, pneumococci and erythrocyte schizonts w/ quinine
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Albuterol MOA
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Beta2 agonist on bronchiolar SM to cause bronchodilation
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Isoniazid
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Blocks mycolic acid synthesis
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What is mycolic acid
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main component of MYCOBACTERIAL cell envelope
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Isoniazid is used for
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TB. It is the best drug for susceptible strains of TB.
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MOA Cimetidine
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H2 Receptor antag
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H2 antags do what
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block histamine, gastrin and Ach effect on Hcl stim
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Contra for Cimetidine
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Renal insuff
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SE of Cimetidine
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Hallucinations, blocks p450 and gynecomastia
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Pantoprazole MOA
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PPI
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Pantoprazole effect reversible or not?
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Not
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Pantoprazole indications
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gerd, PUD, and NSAID associated ulcers
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Pantoprazole contra's
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Gastric Cancer
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SE Pantoprazole
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increases gastrin
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Clarythromycin MOA
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Binds 50s = no growth.
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Clarithromycin indications
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H. pylori, H. influenzae, Mycobacterium, Lyme, and Leprosy
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SE Clarithro
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GI disturbs
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Amoxicillin MOA
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Blocks peptidoglycan synth
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Indications Amoxicillin
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S. pyogenes, H. influenzae, bronchitis, pneumonia, E. coli UTI, Gonorrhea
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Hycoscyamine
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Blocks mAch recptor in enteric plexus to reduce spasms
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Indications of Hyoscyamine
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Pain and diarrhea associated w/ IBS
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Psyllium is a?
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Bulk-forming laxative
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Effects of psyllium?
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Absorb H20, distend colon and promote peristalsis
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Psyllium is for those who lack what in their diet?
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Fiber
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Vecuronium is a?
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Muscle relaxor
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Vecuronium MOA?
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Blocks Ach at end-plate
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Isoflurane is a?
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Anesthetic/sedative
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At what point in surgery is isoflurane used?
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At the start for general anesthesia
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Fentanyl is an?
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Analgesic - an opiod agonist.
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Fentanyl MOA
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µ-opiod receptor agonist, inhibit adenylate cyclase to prevent afferent signals
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Bismuth Subsalicylate MOA
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Reduces PGE2 which reduces GI cl- loss, chelates ulcers, binds toxins. Metab'd to salicylic acid in stom.
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SE Bismuth Sub
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Nausea, vomiting, heartburn, diarrhea
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Contra for bisumuth sub
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Renal probs becuase low PGE2 lowers renal blood flow
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SE Bismuth sub
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Black stools and black tongue if taken for a long time
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Loperamide's trade name is?
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Imodium
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Loperamide MOA?
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opiod receptor agonist that increases the colonic phase and diminishes gastrocolic reflex.
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Indication for Imodium?
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diarrhea
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SE of Imodium?
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Constipation
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Metronidazole MOA
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Damages parasite DNA and inhibits nuceic acid synthesis
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Indications of Metro
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amoebiasis of liver or intestine
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Contra's of metro
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pregnancy or alcohol
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test
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test1
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test
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test2
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