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25 Cards in this Set
- Front
- Back
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5-FU
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Inhibits Thymidylate
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Methotrexate
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Inhibits dihydrofolate reductase
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Hydroxyurea
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Inhibits Ribonucleotide reductase
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Vincristine/Vinblastin
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Inhibits microtubule formation
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Paclitaxel
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Inhibits Microtubules from migating
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Levamisole
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Stimulates Natural Killer (NK) cells
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Steroids
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1. kills T-cells & Eosinophils
2. Inhibits macrophage migration 3. Inhibits phospholipae A 4. Inhibits mast cell degranulation 5. Stabilizes endothelium |
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Statins
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Inhibits HMG CoA reductase
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Niacin
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Decreases VLDL production in the liver
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Sulfonylureas
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1. 1st generation: blocks potassium channels in Islet cells preventing insulin release
2. 2nd generation: promotes insuling release and inhibit gluconeogenesis in the liver |
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Miglitol/Ascarbose
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Inhibits glucose absorption from the GIT
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Metformin
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Stops gluconeogenesis in the liver
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Troglitazone
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Increases the sensitivity of insulin receptors
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Anti-Psychotics
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blocks dopamine receptors
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Aspirin
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Irreversible inhibitor of cyclo-oxygenase
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Potassium sparing diuretics
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competitive aldosterone receptor antagonist
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Topical Anesthetics
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Block Na channels
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Quinalones
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blocks topoisomerase (supercoils)
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Aminoglycosides
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blocks Initiation Factor (IF) 2 on the 30S subunit
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Tetracyclines
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blocks tRNA binding on the 30S subunit
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Rifampin
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blocks beta subunit of RNA polymerase
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Sulfa Drugs
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Blocks para-Amino Benzoic Acid (PABA)
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Cephalosporins
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Inhibits cell wall
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Penicillins
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block transpeptidase
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Chloramphenicol
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blocks peptidyl transferase on the 50S subunit
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