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14 Cards in this Set

  • Front
  • Back
Injury to Cell
• Releases Arachidonic Acid and Bradykinin
• Arachidonic acid→cyclooxygenase→prostaglandins→activating an sensitizing pain receptors
• Injury from temp, physical injury, etc
o →vasodilation→feel red, warm, swelling (edema)→pain cells also innervated
3 Categories for Pain Management
• opiates/opioids or narcotics
• nonopiates
o Acetaminophin, salicylates (ASA_, and NSAIDs
• Adjuvant analgesics
o Benzodiazopines, TCA, Carticosteroids
o Medications not known for their pain relieving ability but because of other things
Pain level to Give opiate
• Pain level 8+→opiate
• Pain level 4-6→non opiate
OR mixture→tylenol w/ codene
Types of Pain
• Duration
o Acute-sudden onset
• →crying, moaning, restless or not moving
• areas of descrete tenderness
o chronic-3 months of more
• not as urgent
• some patients may have depression from it, withdrawl, personal lifestyle change
• arthritic pain, cancer
• Origin
o Somatic-skin, bone, muscle
• Often described as sharp, throbbing, crampy, burning
• Can be acute or chronic
• Can stimulate sympathetic nervous system
 →high BP, HR
o Visceral-more thoracic or abdominal
• Dull, aching
• Can’t immediatey localize it
• If bad enough→have potential to innervate sympathetic NS
 →since it runs through vagus nerve→vagus vagal→BP srops, bradycardic, nausia/vomiting, change of consciousness
o Neuropathic pain-to nerves
• Shooting pain
Pain Assessment
• PQRST
• Precipitates, provokes
• Quality
• Radiation
• Severity
• Timing
Agonist
• A drug that can act LIKE something natural in the body
• Acts like an opiate (pain med)
Antiagonist
block the addiction of it and also blocks receptors
Agonist/Antiagonist
• Opiate that helps pain and wont have any addictive effect
o Prototype Talwin (pentazocine)
o Addict→take talwin→feel withdrawl
o Not as effective as morphine
Opiate Prototype
Morphine
Therapeutic effect of opiates
interferes with pain impulses
Adverse drug effects of opiates
• Depresses GI tract→NV, constipation
• Depresses CNS
o Serious drop in respirations
o Sedation, dizziness (safety issue)
• Alters psycho response to pain
• Euphora
Clinical Uses of opiates
• Relief of moderate to severe pain
o Moderate=4-6 severe=7-10
• Pre-op sedation
• Labor and delivery
• Invasive diag tests
• Acute pulmonary edema
• Severe nonproductive cough
• MI and APE treatment
Opiate Antagonist
• Prototype=narcan
• NOT a stimulant
• Have no agonist effects
• Wont help patient if having issues
• Used to counteract overdose of an opiate
• Happens quickly→lasts about 2 hours
o Need to reassess patient after 2 hours
Withdrawal
• Depressive feelings
• Muscle pain
• Abstinence is the goal
o Methadone→reduce withdrawl
o Surboxone→help them