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14 Cards in this Set
- Front
- Back
Injury to Cell
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• Releases Arachidonic Acid and Bradykinin
• Arachidonic acid→cyclooxygenase→prostaglandins→activating an sensitizing pain receptors • Injury from temp, physical injury, etc o →vasodilation→feel red, warm, swelling (edema)→pain cells also innervated |
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3 Categories for Pain Management
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• opiates/opioids or narcotics
• nonopiates o Acetaminophin, salicylates (ASA_, and NSAIDs • Adjuvant analgesics o Benzodiazopines, TCA, Carticosteroids o Medications not known for their pain relieving ability but because of other things |
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Pain level to Give opiate
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• Pain level 8+→opiate
• Pain level 4-6→non opiate OR mixture→tylenol w/ codene |
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Types of Pain
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• Duration
o Acute-sudden onset • →crying, moaning, restless or not moving • areas of descrete tenderness o chronic-3 months of more • not as urgent • some patients may have depression from it, withdrawl, personal lifestyle change • arthritic pain, cancer • Origin o Somatic-skin, bone, muscle • Often described as sharp, throbbing, crampy, burning • Can be acute or chronic • Can stimulate sympathetic nervous system →high BP, HR o Visceral-more thoracic or abdominal • Dull, aching • Can’t immediatey localize it • If bad enough→have potential to innervate sympathetic NS →since it runs through vagus nerve→vagus vagal→BP srops, bradycardic, nausia/vomiting, change of consciousness o Neuropathic pain-to nerves • Shooting pain |
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Pain Assessment
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• PQRST
• Precipitates, provokes • Quality • Radiation • Severity • Timing |
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Agonist
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• A drug that can act LIKE something natural in the body
• Acts like an opiate (pain med) |
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Antiagonist
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block the addiction of it and also blocks receptors
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Agonist/Antiagonist
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• Opiate that helps pain and wont have any addictive effect
o Prototype Talwin (pentazocine) o Addict→take talwin→feel withdrawl o Not as effective as morphine |
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Opiate Prototype
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Morphine
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Therapeutic effect of opiates
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interferes with pain impulses
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Adverse drug effects of opiates
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• Depresses GI tract→NV, constipation
• Depresses CNS o Serious drop in respirations o Sedation, dizziness (safety issue) • Alters psycho response to pain • Euphora |
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Clinical Uses of opiates
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• Relief of moderate to severe pain
o Moderate=4-6 severe=7-10 • Pre-op sedation • Labor and delivery • Invasive diag tests • Acute pulmonary edema • Severe nonproductive cough • MI and APE treatment |
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Opiate Antagonist
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• Prototype=narcan
• NOT a stimulant • Have no agonist effects • Wont help patient if having issues • Used to counteract overdose of an opiate • Happens quickly→lasts about 2 hours o Need to reassess patient after 2 hours |
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Withdrawal
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• Depressive feelings
• Muscle pain • Abstinence is the goal o Methadone→reduce withdrawl o Surboxone→help them • |