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10 Cards in this Set
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drugs used in treatment of hypertension, heart failure, diabetic nephropathy, and MI
Side effects: angioedema, cough, neutropenia, agranulocytosis, edema, hypotension, rash, gynecomastia, hyperkalemia, proteinuria Contraindications: history of agioededema, bilateral renal artery stenosis, pregnancy, renal failure |
captopril, enalapril, ramipril, benazepril, fosinopril, moexipril, perindopril, quinapril, trandolapril, lisinopril: ACE inhibitors
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drugs used for hypertension, diabetic nephropathy, heart failure, MI, prevention of stroke
side effects: rare thrombocytopenia, rhabdomyolysis, rare angioedema, hypotension, diarrhea, asthenia, dizziness contraindications: bilateral renal artery stenosis, pregnancy |
candesartan, irbesartan, losartan, telmisartan, valsartan: angiotensin II receptor antagonists
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drug used in acutely decompensated heart failure
side effects: hypotension, cardiac arrhythmia, renal dysfunction, headache, confusion, somnolence, tremor, pruritus, nausea contraindications: cardiogenic shock, systolic BP less than 90 |
Nesirtitide: B-Type natriuretic peptide
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drugs used for euvolemic hyponatremia, SIADH, heart failure, cirrhotic ascites, autosomal dominant polycystic kidney disease
side effects: Afib, orthostatic hypotension, peripheral edema, injection site reaction, hypokalemia, thirst, dyspepsia, headache, polyuria contraindications: concurrent use of potent P450 3A4 inhibitors, hypovolemic hyponatremia |
Conivaptan, lixivaptan, tovaptan: vasopressin receptor antagonists
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drugs used for high altitude sickness, heart failure, epilepsy, glaucoma
side effects: metabolic acidosis, sulfonamide adverse reactions, diarrhea, weight and appetite loss, tinnitus, nausea, vomiting, paresthesia, somnolence, polyuria contraindications: adrenal gland failure, chronic angle-closure glaucoma, cirrhosis, hyponatremia/hypokalemia, hyperchloremic acidosis, servere hepatic/renal disease |
acetazolamide: carbonic anhydrase inhibitors
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drug used for cerebral edema, increased intraocular pressure, prophylaxis of oliguria in acute renal failure
side effects: thrombophlebitis, acidosis, seizure, urinary retention, pulmonary edema, hypotension, palpitations, fluid and/or electrolyte imbalance, diarrhea, nausea, rhinitis contraindications: anuria, severe dehydration, heart failure, pulmonary congestion, or renal dysfunction after initiation |
mannitol: osmotic diuretics
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drugs used for hypertension, acute pulmonary edema, edema associated with CHF/hepatic cirrhosis/renal dysfunction, hypercalcemia, hyperkalemia
side effects: hypotension, erythemia multiforme, stevens-johnson syndrome, pancreatitis, aplastic or hemolytic anemia, leukopenia, thrombocytopenia, volume contraction, alkalosis, ototoxicity, hypokalemia, hyperuricemia, hypomagnesia, hyperglycemia, rash, cramps, spasticity, headache, blurred vision, dyspepsia, glycosuria Contraindications: hypersensitivity, anuria, coadministration with aminoglycosides |
furosemide, bumetanide, torsemide, ethacrynic acid
loop diuretics |
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drugs used for hypertension, adjunct in edema states associated with CHF, hepatic cirrhosis, renal dysfunction, corticosteroid and estrogen therapy
side effects: cardiac arrhythmias, steven johnson syndrome, toxic epidermal necrolysis, pancreatitis, hepatotoxicity, SLE, hypotension, vasculitis, photosensitivity, electrolyte abnormalities, hypokalemic met alkalosis, hyperglycemia, hyperurcemia, dyspepsia, headache, blurred vision, impotence, restlessness contraindications: anuria, hypersensitivity, coadministration with agents that prolong QT interval |
hydrochlorothiazide, bendroflumethiazide, hydroflumethiazide, polythiazide, chlorthalidone, metolazone, indapamide: thiazides
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drugs used in hypertension, edema associated with CHF/liver cirrhosis/or nephrotic syndrome, hypokalemia, primary aldosteronism, acne vulgaris (s), femal hirsutism
side effects: hyperkalemic met acidosis, GI hemorrhage, agranulocytosis, SLE, breast cancer, gynecomastia, dyspepsia, lethargy, abnormal menstruation, impotence, rash contraindications: anuria, hyperkalemia, acute renal insufficiency |
spironolactone, eplerenone: K+ sparing diuretics that bind aldosterone
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drugs used for hypertension and liddle syndrome
side effects: diseases of hematopoietic system, nephrotoxicity, hyperkalemic met acidosis, orthostatic hypotension, hyperkalemia, dyspepsia, headache contraindications: anuria, hyperkalemia, acute renal insufficiency |
amiloride, triamterene
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