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62 Cards in this Set

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Metabolite
A chemical form of a drug that is the product of one or more biochemical, metabolic reactions involving a parent drug.
Onset of action
The time it takes for the drug to elicit a therapeutic response.
Parent drug
The chemical form of a drug that is administered to the body before it is metabolized by the body's biochemical reactions into its active or inactive metabolites.
Peak effect
The time it takes for a drug to reach its maximum therapeutic response in the body.
pharmaceutics
The science of dosage form design (eg tablets, capsules, injections, patches, etc)
Pahrmacodynamics
The study of the boichemical an physiologic interactions of drugs. It examines the physiologic interactions of drugs. It examines the physicochemical properties of drugs and their pharamcologic interactions with suitable body receptors.
Pharmacogenetics
The study of genetic factors and their influence on drug repsonse. Investigates the nature of genetic aberrations that result in the absence, overabundance, or insufficiency of drug-metabolizing enzymes.
Pharmocognosy
The study of drugs that are obtained from natural palnt and animal sources.
Pharmacokinetics
study of drug distribtuion rates between various body compartments after a drug has entered the body. Includes absorption, distribution, metabolism, and excreation.
Pharmacology
Study or science of drugs
Pharmacotherapeutics
treatment of pathologic conditions through the use of drugs. 2 kinds empirical and rational
Prodrug
An inactive drug dosage from that is converted to an active metabolite by various biochemical reactions in the body. Usually more readily absorbable than its active metabolite
Receptor
A molecule structure within or on the outer surface of cells. Characterized by the binding of specific substances and one or more corresponding cellular effects.
Side effect
Any undesireable effect of a medication that is expected or anticipated to occur in a predicatble percentage of clients who recieve a given medication.
Steady state
The physiologic state in which the amount of drug removed via elimination is equal to the amount of drug absorbed with each dose.
Substrate
substance on which an enzyme acts
synergistic effect
drug interaction that results from combined drug effects that are greater than those that could have been achieved if the drugs were given alone.
Syrup of Ipecac
used to induce vomiting
Therapeutic effect
desired or intended effect of a particular medication
Theraeutic index
difference between the minimum therapeutic and toxic concentrations of a drug.
Toxic
The state of being poisonous
Toxicology
Study of poisoins.
Trade name
final name given to a drug: also called proprietary name.
Polypharmacy
The use of many different drugs.
Blinded investigational drug study
research method which the subject taking the drug under study is purposely unaware of a key element in the study
Canadian Food and drugs Act
amended many times since its inception in 1953, this act is the main piece of drug legislation in Canada
Canadian Narcotic control act
addresses the posession sale manufacture, etc of drugs
Controlled substance act 1970
promotes research on drug abuse, prevention of and treatment for
drug polymorphism
variation in response to a drug because of a patient's age, gender, size and body composition
Durham Humphrey amendment of 1951
amendment to FDA regulates between OTC's and RX's
Expeditied drug approval
hasting of the usual IND approval process by USFDA and pharmaceutical companies in response to pubilc health threat.
Federal Food and Drug Act 1906
1st fed law that attempted to protect the public from dangerous, adulterated, and mislabeled products.
Federal food drug and cosmetics act 1938
required drug makers to apply for an IND exemption for safety review before marketing new drugs
Harrison Narcotic act 1914
Established term narcotic
informed consent
permission obtained from a client consenting to the performance of a specific test or procudure.
Investigational new drug IND
drug not approved for marketing by the FDA but available for use in experiments to determine its safety
Kefauver Harris amendment of 1961
required drugs to be proved both safe & effective before being granted an approved status.
Legend drugs
another name for RX
New drug application NDA
once a drug successfully completes the first three phases of an IND study, the drug manufacturer may submit a new drug application
Orphan drug act 1983
aid in the development of drugs for the treatment of "rare" disease.
Orphan drugs
distinct, special category of drugs that have been identified to help clients with rare diseases
Sherley Amendment 1912
prohibited the labeling of medicines with false therapeutic claims intending to defraud the consumer.
nonmaleficence
the duty to do no harm to a client.
veracity
duty to tell the truth
autonomy
ability to act on one's own
beneficence
the doing or active promotion of good
adverse drug event
injury caused by a medication or failure to administer an intended medication.
latrogenic hazard
any potential or actual patient harm that is caused by errant actions of health care staff members
idiosynctratic reaction
abnormal and unexpected suscetibility to a medication, other than an allergic reaction that is peculiar to an individual patient.
medication error ME
preventable inappropriate medication error.
medication misadventrue MM
broadest term for any undesirable medication related event that was caused by health care workers.
Amphetamines
Durgs that stimulate the central nervous systems
Enuresis
Urinary Incotinence
Illicit Drug Use
use of a drug or substance that is not intended to be used in the manner in which it is being used. not legally proved for human consumption.
Micturition
Urination, the desire to urinate, or the frequency
Narcotic
any agent that produces insensibility or stupor. applies mostly to opiods.
Opioid analgesics
synthetic pain reliving substance that originated from the opium plant.
physical dependance
condition characterized by physiological reliance on a substance.
Psycoactive properties
mood, anxiety, behavior,cognitive processes, and mental tension.
Psychologic dependence
a condition characterized by behaviors releated to obtaining and using a substance.
Raves
Increasingly popular all night parties that typically involve dancing drinking and the use of various illicit drugs
Roofies
Pills that are classified as benzodiazepines. they have recently gained popularity as a recreational drug. chemically known as flunitrazepam