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13 Cards in this Set
- Front
- Back
- 3rd side (hint)
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Pharmacology
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science of drugs including origin, composition, pharmacokinetics
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Pharmacognosy
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study of medicines derived from natural sources
drug knowledge |
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Pharmacodynamics
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study of the actions of a drugs on the body
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4 Effects of Pharmacodynamics
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Depression
Stimulation Irritation Demulcence |
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Pharmacodynamic:
Agonist |
Another drug that acts similar to another drug already present in the body that does a similar effect.
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I have serotonin in body but then I take an OTC which does similar effect but does have varying effects.
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Pharmacodynamics:
Antagonist |
Binds to receptors but NO rxn occurs, prevents other drugs from binding.
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Prevents the natural (human made) drug from binding
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Therapeutic Index
TI |
Ratio between toxic dose and therapeutic dose,
Larger the number the safer it is. |
TI= TD50/ED50
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Toxic Dose
TD |
Amount that produces a toxic effect in 50% of the population
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Therapeutic Dose
ED50 |
Drug dose that produces a therapeutic effect in 50% of the population.
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Therapeutic Margin
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Expression of the TI as measure of drug safety.
Smaller the TI the more deadly/toxic the drug is. Narrow TM: Warfarin, Phenytoin, Lithium |
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Routes of Administration
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Enterally: via GI Tract
Percutaneous: via the Skin Parenteral: Injection/IV |
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Enteral Routes
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Oral: GI Tract
Rectal: Suppository/enema Nasogastric: nose to stomach Gastric: Catheters into the stomach |
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Percutaneous Routes
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Absorbed through skin or mucous membranes
Sublingual and Buccal: mouth Topical Local vs. Systemic effects |
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