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227 Cards in this Set
- Front
- Back
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What is used for post op ileus and urinary retention?
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Bethanechol
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What is carbachol? Use?
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cholinomimetic
glaucoma |
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What is pilocarpine? Use?
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cholinomimetic
glaucoma (open and closed) PILE on the sweat and tears. |
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What is used as a challenge test for asthma diagnosis?
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Methacholine
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What are the anticholinesterases that penetrate the CNS? Use?
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physostigmine
Glaucoma, Atropine OD |
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What is Neostigmine used for?
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post op ileus/urinary retention
Myasthenia Gravis postop reversal of neuromusc blockade |
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What are the drugs that can be used for Myasthenia Gravis?
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anticholinesterases
Neostigmine Pyridostigmine Edrophonium (test to see if tx is low or too high - inactivation) |
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What is the antidote for cholinesterase inhibitor poisoning?
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atropine
pralidoxime (regen cholinesterase) |
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How can you get cholinestase inhibitor poisoning?
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Parathion
organophosphates |
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What M - antagonist is used for parkinson's disease?
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Benztropine
PARKinsons your BENZ |
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What is scopolamine? Use?
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M ant
motion sickness |
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What is the M ant used for asthma, COPD?
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Ipratroprium
I Pray I can breathe soon!! |
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What are specific toxicities associated with atropine?
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baby : high temp
old man: no pee old peeps: closed angle glaucoma |
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What is the treatment for atropine OD?
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physostigmine
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volume of distribution =
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amt drug adminstered / plasma conc
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clearance of a drug =
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rate of elimination/plasma conc
k x volume of distribution |
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half life =
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(.7 x Vd) / Clearance
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loading dose =
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Cp x Vd/bioavailability
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bioavailability =
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AUC oral x IV dose / AUC IV x oral dose
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maintenance dose =
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Cp x Clearance/bioavailability
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What does zero order elimination mean?
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fixed amount of drug is eliminated per unit time
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What drugs show zero order elimination?
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phenytoin, ethanol, aspiring
(PEA looks like zero) |
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What drugs are weak acids and what do you do for OD?
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phenobarbitol, methotrexate, TCAs, aspirin
tx OD with bicarbonate |
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What happens in phase 1 metabolism?
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Cyt p 450
red, ox, hydrolyze - makes more water soluble but can still be active |
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What happens in phase 2 metabolism?
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conjugation
acetylation, glucuronidation, sulfation - yields very polar, inactive metabolites |
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Competitive inhibitors don't change the enzymes ________.
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Vmax
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Non-competitive inhibitors don't change the enzymes ________.
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Km
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What occurs with alpha 1 excitation?
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vasocontr, high BP/R
mydriasis high glucose decrease pee/GI fn |
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What occurs with alpha 2 excitation?
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decreased symp response
decrease insulin section decreased platelet aggregation |
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What occurs with beta 1 excitation?
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increased HR, contractility, renin
increased lipolysis |
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What occurs with beta 2 excitation?
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vasodil
bronchodil increased insulin (and blood glucose??) decreased uterine tone - delay birthing |
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What receptors are Gq?
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H1, alpha 1, V1
M1, M3 HAVe 1 M&M |
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What receptors are Gi?
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M2, alpha 2, D2
MAD 2's |
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What is isoproterenol used for?
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AV block
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What is dopamine used for?
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Shock
heart failure |
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What is dobutamine used for?
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shock
heart failure cardiac stress testing |
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What is phenylephrine used for?
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cause
pupillary dilation vasoconstriction nasal decongestion |
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What is terbutaline/ritodrine used for?
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sympathomimetic
used to reduce premature uterine contractions |
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What are sympathomimetics that are used for asthma treatment?
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albuterol (acute)
salmeterol (long term) |
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How do cocaine, ephedrine and amphetamines work?
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amphetamines/ephedrines - released stored catecholamines
cocaine - catecholamine uptake inhibitor |
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What are the applications of amphetamines?
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narcolepsy
obesity ADD |
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What are the applications for ephedrine?
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nasal decongestion
urinary incontinence hypotension |
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What is clonidine? Use?
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alpha 2 agonist.
HTN, esp with renal disease |
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What is methyldopa? Use?
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alpha 2 agonist
prego HTN |
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What drug can be used before removing a pheo?
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non selective alpha blockers
phenoxybenzamine (noncompetitive)... can't use phentolamine cuz that's competitive and will be overwhelmed by high NE/E |
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What can prazosin be used for?
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alpha 1 blocker
HTN urinary retention in BPH |
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What is the antidote for acetaminophen poisoning?
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N-acetylcysteine
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What is the antidote for salicylates poisoning?
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bicarb - alkalinize urine
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What is the antidote for amphetamine poisoning?
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ammonium chloride - acidify urine
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What is the antidote for B blocker poisoning?
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glucagon
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What is the antidote for iron poisoning?
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deferoxamine
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What is the antidote for lead poisoning?
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EDTA, dimercaprol, penicillamine
'the lead patrol" |
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What is the antidote for copper poisoning?
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penicillamine
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What is the antidote for cyanide poisoning?
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nitrates -
convert Hb to metHb, which binds CN better --- allows cyt oxidase to work |
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What is the antidote for methemoglobin poisoning?
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Methylene blue
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What is the antidote for opiods poisoning?
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naloxone, naltrexone
mu receptor antagonists |
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What is the antidote for benzo poisoning?
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flumazenil
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What is the antidote for TCAs poisoning?
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sodium bicarb - serum alkalinize
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What is the antidote for heparin poisoning?
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protamine
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What is the antidote for warfarin poisoning?
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Vit K, fresh frozen plasma
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What is the antidote for theophylline poisoning?
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B blocker
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What drugs cause coronary vasospasm?
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cocaine
sumatriptan |
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What drugs cause cutaneous flushing?
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vancomycin
adenosine nitrates CCBs VANC |
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What drugs cause torsades de pointes?
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quinidine (class 1A)
sotalol (class 3) cuz prolong QT interval!!!! |
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What drugs cause agranulocytosis?
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clozapine (schizo)
carbamazepine (bipolar, partial/tonic clonic seizures) colchicine propylthiouracil (hyperthyroid) dapsone (leprosy) |
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What drugs cause aplastic anemia?
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carbamazapine
chloramphenicol propylthiouracil |
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What drugs cause grey baby syndrome?
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chloramphenicol
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What drugs cause hemolysis in G6Pd deficient patients?
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INH
sulfonamides primaquine aspirin/ibuprofen |
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What drugs cause megaloblastic anemia?
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phenytoin
methotrexate sulfa drugs having a BLAST with PMS |
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What drugs cause pulmonary fibrosis?
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amiodarone
bleomycin busulfan (alkylating agent) |
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What drugs cause acute cholestatic hepatitis?
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Macrolides
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What drugs cause hepatic necrosis?
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Halothane
Valproic acid (tonic clonic, myoclonic seizures) acetaminophen |
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What drugs cause hepatitis?
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INH
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What drugs cause pseudomembranous colitis?
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clindamycin
ampicillin |
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What drugs cause boobs?!
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spironolactone
digitalis cimetidine alcohol ketoconazole Some Drugs Create Awesome Knockers |
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What drugs cause hypothyroidism?
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lithium
amiodarone |
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What drugs cause gingival hyperplasia?
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phenytoin, verapamil
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What drugs cause gout?
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furosemide
thiazide |
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What drugs cause osteoporosis?
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corticosteroids
heparin |
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What drugs cause photosensitivity?
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sulfonamides
amiodarone tetracycline |
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What drugs cause Steven Johnson's syndrome?
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ethosuximide, lamotrigine, phenytoin, carbamazepine, phenobarbital
sulfa drugs PCN allopurinol |
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What drugs cause SLE-like syndrome?
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* dev anti histone Ab
hydralazine INH phenytoin procainamide it's not HIPP to have lupus |
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What drugs cause tendonitis?
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fluoroquinolones
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What drugs cause interstitial nephritis?
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methicilin
NSAIDs furosemide sulfonamides rifampin |
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What drugs cause hemorrhagic cystitis?
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cyclophosphamide (prevent with mesna)
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What drugs cause diabetes insipidus?
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lithium
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What drugs cause parkinson-like syndrome?
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haloperidol
chlorpromazine - can give benztropine anti-ach for this reserpine (prevent DA from being packaged into NE vesicles) metoclopramide (D2 rec ant for post surgery gastroparesis) |
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What drugs cause seizures?
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bupropion (atypical antidepressant. used for smoking cessation)
imipenam/ciastatin isoniazid (cuz B6 deficiency) |
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What drugs cause a disulfiram-like reaction?
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metronidazole
some cephalosporins 1st gen sulfonylureas |
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What drugs cause nephro and ototoxicity?
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aminoglycoside
vanco loop diuretic cisplatin (cross link DNA) |
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What drugs are p450 inducers?
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carbamezepine, barbs, phenytoin
rifampin griseofulvin chronic alcohol |
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What drugs are p450 inhibitors?
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Sulfonamide
Isoniazid Cimetidine Ketoconazole Acute alcohol Grapefruit juice Erythromycin |
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What kinds of drugs can be used for glaucoma?
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alpha agonist (but not in closed angle) - epinephrine
beta blockers - timolol, carteolol diuretics - acetazolamide cholinomimetics - pilocarpine, carbachol, physostigmine prostglandin - latanoprost |
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Name the basic opiods
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codeine, morphine, heroine, fentanyl, dextromethorphan, meperidine, methadone
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What is the basic opioid mechanism?
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open K channels - decrease synaptic transmission
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What drug can be used to decrease tolerance to morphine?
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Ketamine - NMDA receptor blocker which inhibits Glu actions
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What are first line drugs for
partial tonic/clonic absence status |
partial - carbamazapine
tonic/clonic - phenytoin, carbamazapine, valproic acid absence - ethosuxamide status - benzos, phenytoin |
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What drug is used for trigeminal neuralgia?
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carbemazepine
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What drug is used for myoclonic seizures?
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valproic acid
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What is the mechanism of phenytoin?
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increases Na channel inactivation
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What are SE of carbamazapine?
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diplopia
ataxia agranulocytosis, aplastic anemia Stevens Johnson syndrome induce p450 |
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What are the SE of phenytoin?
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eye stuff - nystagmus, diplopia
ataxia SLE like syndrome uggo- gingival hyperplasia, hirsuitism, acne, general lymphadeno megaloblastic anemia induce p450 |
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What is unique about thiopental?
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short acting barbituate used for anesthesia induction
rapid redistrib to tissue/fat - rapid recovery from anesthesia |
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What are the different benzos and which ones are most addictive?
|
short acting -
zolpidem (acts like benzo but isn't) alprazolam - highest addictive potential mediam - lorazepam long - diazepam |
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What are the characteristics of anesthetics that have rapid induction?
|
low solubility in blood = low blood/gas coeff = low A/V gradient
(anesthetic starts to work in brain after equilibration in blood) |
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What are the characteristics of anesthetics that have a high potency?
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high solubility in lipids = high potency = 1/MAC
MAC = conc where 50% of population is anesthetized |
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What is malignant hyperthermia?
what drugs cause it? what's the treatment for it? |
- abnormal ryanodine rec release lots of Ca post anesthesia
- ATP dep sarcoplasmic reuptake - fever, ridigity seen with inhaled (halothane, NO, enflurane) and succinylcholine tx: dantrolene |
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What are the categories and names of local anesthetics?
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esters - one I
amIdes - two I's |
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What is the mechanism of local anesthetics?
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Block Na channels
usu given with epi to enhance local action |
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What is the order of nerve blockade for local anesthetics?
|
small myelinated
small unmyelinated large myelinated large unmyelinated |
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What are the different kinds of neuromuscular blockers?
|
depolarizing - succinylcholine (acts like Ach)
(can't reverse in prolonged depol phase. reverse with neostigmine in repolarized but blocked phase) non-depolarizing - tubocurarine - compete with Ach for receptors reverse with neostigmine |
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What drugs agonize DA receptors in PD?
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pramipexole
bromocriptine |
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What drugs increase dopamine in PD?
|
Amantadine (also an antiviral)
L-dopa/Carbidopa (decarboxylase inhibitor) |
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What drugs prevent DA breakdown?
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MAO-inhib
- selegiline COMT inhib - entacapone (peripheral) - tolcapone (in brain) |
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What are the SE of levodopa/carbidopa?
|
On/off phenomena
behavioral changes w/o carbidopa, get N/V, tachyarrhythmias, postural hypotension, hot flashes |
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What are the drugs used for Alzheimer's disease?
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Memantine - NMDA ant - prevents excitotoxicity
Donezepil - Ach-esterase inhib |
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What drug can be used for acute migraines and how does it work?
|
Sumatriptan
5-HT agonist - vasoconstric - inhib trigeminal activation SE: coronary vasospasm |
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What are the low potency antipsychotics and their SE?
|
thioridazine - reTinal deposits
chlorpromazine - Corneal deposits block M (dry mouth, constip) block H (sedation) block alpha (hypotension) |
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What are high potency antipsychotics and their SE?
|
haloperidol, fluphenazine, trifluoperazine
4 hrs - dystonia 4 days - akinesia (use benztropine) 4 wks - akasthia (restlessness) 4 mo - tardive dyskinesia |
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What are the atypical antipsychotics and their mechanism of action?
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olanzapine
clozapine quietiamine risperidone aripiprazole ziprasidone block 5-HT, alpha, histamine and DA rec use for + and - schizo symptoms |
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What are drugs for bipolar disease?
|
carbamazapine
lithium valproic acid |
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What are the SE of lithium?
|
tremor
DI hypothyroidism ebstein's anomaly |
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What is busipirone?
|
stim 5-HT receptors
for generalized anxiety disorder no sedation, low abuse potential |
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What are the names of tricyclics and their major SE?
|
imiPRAMINE, amiTRIPTYLINE, doxepin
convulsions coma cardiotoxicity (arrythmias, hypotension) mimic atropine cytotoxicity |
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Name some SSRIs
|
fluoxetine
sertraline paroxetine citalopram |
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What is Serotonin syndrome and what drugs cause it?
tx? |
SSRIs and MAOi
hyperthermia, rigidity, myoclonus cardiovascular collapse, seizures tx: cyproheptadine |
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What drug can be used for diabetic peripheral neuropathy?
|
duloxetine
|
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Name some MAO-i
|
phenelzine
selegiline (used in PD) |
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What is the mechanism of MAOi
|
block MAO - increase levels of amine NTs (5-HT, DA, NE)
btw, these ARE NOT first line drugs cuz of associated dietary restrictions |
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Mechanism of tricyclics
|
inhib NE and 5-HT uptake
|
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What is an atypical antidepressant used for insomnia?
|
Trazodone.... causes priapism!
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What is Bupropion used for?
|
smoking cessation. good alternative if SSRIs cause sexual dysfn.
increases NE and DA. can cause seizures no sexual SE |
|
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What drugs are associated with fat redistribution?
|
glucocorticoids and HAART
|
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What are anti-M effects and what drugs cause them?
|
flushed skin, mydriasis, dry skin, cant pee....
atropine TCA H1 receptor antagonists low potency antipsychotics |
|
|
What kind of glaucoma is acute w/ headache and pain?
cause tx |
narrow angle
cause: anti-chol tx - B blockers: decrease aq humor prod by ciliary epith cholimimetics (pilocarpine, carbachol) - increase outflow |
|
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What are the SE of niacin?
|
flushed face (high PGE.. prevent with aspirin)
hyperglycemia hyperuricemia |
|
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What lipid lowering agents cause gallstones ?
|
fibrates (gemfibrozil)
resins (cholestyramine) |
|
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What is the mechanism of niacin?
|
reduce VLDL secretion.
inhibit lipolysis in adipose tissue |
|
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What lipid lowering agents cause increases in LFTs?
|
statins, gemfibrozil
|
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What lipid lowering drugs cause muscle problems?
|
stains, gemfibrozil
|
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What is the mechanism of gemfibrozil?
|
upreg LPL - increased TG clearance
|
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What drugs are used for stress testing?
|
Dobutamine and adenosine
|
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What is the cellular cascade caused by NO or nitrates?
|
high cGMP - low intracel Ca - myosin gets dephosphorylated - dilated vessels
|
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What are the SE of amphotericin?
|
renal toxicity - low serum K/Mg
have to supplement those vitamins and drink lots of water |
|
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What receptors does epi work on?
|
alpha 1/2, beta 1/2
|
|
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What do D1 receptors do?
|
relax renal vascular smooth muscle
|
|
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What is the mechanism and excretion of Digoxin?
|
mechanism -
block Na/K - block Na/Ca - more intracel Ca - greater strength of contraction also stim vagus - slow AV node cond excretion - RENAL! |
|
|
Digoxin SE
|
blurry yellow vision, delirium
hyperK, arrhythmia (V tach) N/V, diarrhea tx: normalize K, lidocaine, anti-dig Fab fragments |
|
|
Hydralazine mechanism and SE
|
mech: vasodil arterioles
SE: reflex symp activation - tachy, edema, lupus-like syndrome |
|
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Which drugs can be used for atrial arrhythmias?
|
class IA, verapamil
|
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Name Class 3 antiarhythmics.
|
amiodarone
bretylium ibutilide sotelol dofetilide |
|
|
Name Class 1 antiarhythmics.
|
1A - quinidine, procainamide, disopyramide
1B - Lidocaine, Mexiletine, Tocainide 1C - Flecainide, Encainide, Propafenone |
|
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What hormones use the cAMP signaling pathway?
|
flat champ CG
FSH LH ACTH TSH CRH hCG ADH MSH PTH calcitonin Glucagon |
|
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What anti-arrhythmics increase the length of an action potential?
|
Class Ia, Class 3
|
|
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What is the preferred drug for supraventricular tachycardia?
|
Adenosine
|
|
|
What are the SE of amiodarone?
|
pulm fibrosis
hepatotoxicity hypo/hyper thyroid corneal deposits blue/grey skin photosensitivity |
|
|
What are the SE of quinidine?
|
cinchonism - headache, tinnitus
thrombocytopenia torsades de pointes |
|
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What antiarrhythmics increase the PR interval?
|
B blockers, CCBs
|
|
|
What are SE of mannitol?
|
pulm edema
|
|
|
What is the mechanism of mannitol?
|
osmotic diuretic. (increase plasma and tubular osm) - use to decrease intracranial/intraocular pressure
|
|
|
What are the indications for azetazolamide?
|
glaucoma
urinary alkalinization metab alkalosis altitude sickness |
|
|
What are the SE of furosemide?
|
Ototoxicity
HypoK Dehydration Allergy Nephritis Gout also, hypo K, Mg, Ca |
|
|
What are the SE of thiazides?
|
hyperGLUC
glycemia lipidemia uricemia calcemia also hypo K, Mg, Na |
|
|
If patient is on Li, can't take what diuretic?
|
thiazide
cuz Li gets reabs with Na in collecting ducts - toxic |
|
|
Name the K sparing diuretics
|
Aldo Ant
Spironolactone Eplerenone Na channel blockers in CT Amiloride Triamterene |
|
|
What are the SE of spironolactone?
|
antiandrogen effects - testicular atrophy, gynecomastia, impotence
|
|
|
What diuretics cause acidemia?
|
Carbonic anhydrase inhibitors
K sparing |
|
|
What diuretics cause alkalemia?
|
Loop and thiazides
|
|
|
What medicine blocks the actions of adenosine?
|
Theophylline which causes bronchodil
|
|
|
What med is used for pulm HTN?
|
Bosentan
|
|
|
What are the SE of PDE inhibitor used for asthma?
|
theophylline
cardiotoxic, seizures. metab by p450 |
|
|
What drug is a GnRH analog?
Use? |
Leuprolide
infertility (pulsatile) prostate ca (continuous w/ flutamide) uterine fibroids |
|
|
What is testosterone used for?
|
hypogonadism
dev secondary sex traits stim anabolism to promote recovery after burn/injury |
|
|
What does ketoconazole do?
|
inhibits desmolase (and therefore steroids synthesis)
in PCOS - prevent hirsuitism (so does spironolactone) |
|
|
What does spironolactone do in reproduction system?
|
inhibits steroid binding...
in PCOS - prevent hirsuitism (so does ketoconazole) |
|
|
What does Clomiphene do?
|
partial agonist at E rec in hypoth - prevents normal feedback inhib - increase release of LH/FSH -
stim ovulation tx for infertility and PCOS |
|
|
What is Anastrozole?
|
Aromatase inhib used in postmeno women with breast ca
(inhib androstenedione to estrone conversion) |
|
|
What drugs are typically used to induce abortion?
|
Mifepristone (P inhibitor @ receptor)
Misoprostol (PGE1 - induce contractions) |
|
|
How does viagra work?
|
inhibit cGMP PDE -
increase cGMP - smooth muscle relaxation in penis - increased blood erection.. yeow! |
|
|
LT C/D/E function?
|
broncho/vaso constriction
increased permeability |
|
|
PGI function?
|
decreased plt aggregation
broncho/vaso dilation decreased uterine tone |
|
|
PGE function?
|
vasodil
pain increased uterine tone - abortifactant maintain GI mucous barrier increased temp maintain patent ductus arteriosus |
|
|
TXA2 function?
|
increased plt aggregation
vasoconstriction bronchoconstriction |
|
|
What is the mechanism of fluid retention with NSAID use?
|
PGE's inhibited - so less vasodil -
relative ischemia kidneys retain H20 and Na |
|
|
In what specific situations are NSAIDs prohibited?
|
CHF
Li use |
|
|
What is the treatment for CMV?
|
Ganicyclovir
if don't work, Foscarnet |
|
|
Drugs that cause colored vision changes?
|
Digoxin
Ethambutol (TB) |
|
|
What lipid lowering drug increases TG?
|
Cholestyramine
|
|
|
What drug has a similar effect on platelet aggregation as aspirin?
|
Clopidogrel, ticlopidine
|
|
|
How are heparin and enoxaparin different?
|
enoxaparin - (low molecular weight heparin)
high bioavail, longer half life, no need for monitoring |
|
|
What is HIT
instead use? |
heparin induced thrombocytopenia
heparin binds plts - autoAb destroy platelets and overactivate remaining ones - so thrombytopenia and hypercoag at the same time! instead use - lepirudin/bivalirudin/argatroban these directly inhibit thrombin |
|
|
What is the different b/w efficacy and potency?
|
efficacy = Emax (does dont matter)
potency = dose req to prod certain effect - dep on drug-rec affinity and drug access to tissue |
|
|
What drug irrev blocks ADP rec and inhibits plt aggregation?
SE? |
clopidogrel/ticlopidine
neutropenia |
|
|
What is the function of
Cox 1 and Cox 2 |
COX 1 - GI, plt stuff
COX 2 - inflam |
|
|
SE of opioids?
|
Sphincter of Odi contraction
|
|
|
What lipid lowering drugs are used to treat high TG?
|
Niain
Fibrates |
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names of protease inhibitors
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ritoNAVIR, saquiNAVIR
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SE of protease inhibitors
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hyperglycemia
lipodystrophy GI sympt inhib p450 |
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What is a nucleoside RT inhibitor? SE?
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ZidoVUDINE, zalcitaBINE
SE: BM suppression, lactic acidosis, megaloblastic anemia |
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Names of non-nucleoside RT inhibitors?
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Nevirapine, Efavirenz, Delavirdine
NEVIR EFAVer Deliver |
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Use of heparin
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immediate anticoag for
PE, stroke, acute coronary syndrome, MI, DVT |
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Use of warfarin
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chronic anticoag for thromboemb
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What drugs inhibit DHF reductase?
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methotrexate
trimethoprim pyrimethamine |
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Name alkylating agents
function? |
cisplatin, cyclophosphamide, busulfan
cross link DNA |
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What do dactinomycin/doxorubicin do?
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intercalate DNA
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What drugs block at the G2 phase? How?
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bleomycin - causes DNA breaks
etoposide - inhib topoisom II |
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What drugs decrease purine synth?
Differences in activation and excretion? |
6-MP and 6-TG
both activated by HGPRT 6-MP excreted by xanthine oxidase - toxicity with allopurinol |
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What is trastuzumab
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AKA herceptin
AntiB against HER-2 (erb-B2) use in metastatic breast ca |
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What is imatinib?
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Philly chr bcr-abl kinase inhib
use in CML |
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What is azathioprine?
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interferes with purine synth ... prodrug form of 6-MP
use in transplantation |
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name NSAIDs
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ibuprofen
naproxen indomethacin ketorolac |
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Acetominophen mechanism
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COX inhib in CNS (analgesic, anti-pyretic)
inactiv peripherally |
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Name bisphosphonates
mechanism? |
etiDRONATE
analog of pyroP (component of hydroxyapatite) - inhib osteoclast activity |
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What are acute gout tx?
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NSAIDs
colchicine - impair PMN chemotaxis GC (if renal failure) |
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What are the TNF inhibitors?
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Etanercept - decoy receptor
Infliximab - anti-TNF antiB Adalimumab - blocks receptor *** do PPD test before beginning therapy |
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What insulin is used
post meal DKA super long acting |
lispro/aspart
regular glargine |
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mechanism of Sulfonylurea?
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close K channel - depol cell - Ca influx - release insulin
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glitazone mechanism
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decrease insulin resistance by changing glu/lipid metab genes
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glitazone SE?
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weight gain, edema, CV toxicity
Hepatotoxic |
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Mechanism of methimazole
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inhib thyroid peroxidase (like propylthiouracil)
btw, propylthiouracil also decreases peripheral T4 to T3 converson |
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What is sucralfate?
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(like Bismuth.. peptobismol)
use for ulcer healing, travelers diarrhea |
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What is sulfasalazine?
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combo of
sulfapyridine (antibacterial) 5-aminosalicylic acid (inhib PGE and LT synth durng inflam) use for UC, Crohns |
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Drug for cirrhosis related hepatic encephalopathy?
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lactulose
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What is an antiemetic for chemo patients?
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ondansetron... 5-HT antagonist
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Name the 1st generation H1 blockers.
SE? |
diphenhydramine, chlorpheniramine
SE - sleepy, anti-M, anti-alpha adren |
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Name the 2nd generation H1 blockers
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Loratidine, cetirizine
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What drugs cause softies?
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anti-HTN
SSRIs neuroleptics ethanol |
