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36 Cards in this Set
- Front
- Back
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What thyroid replacement med is preferred?
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none really, but the most common is synthroid
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What is the typical starting dose of thyroid replacement for a younger person?
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100mcg/qd
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What is the typical starting dose of thyroid replacement for an older adult?
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25-50 mcg/day and titrate slowly
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What is the 1/2 life of thyroid replacement?
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7 days
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nervousness, weakness, heat intolerance, sweating, wt. loss, thin skin, exophthalmos, loose stools are all s/s of ?
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hyperthyroidism
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When should TSH/T4 levels be checked?
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At 6 weeks
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If a pt's T4 is normal and
TSH is normal, how should you adjust the thyroid dose? |
don't leave it alone
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If a pt's T4 is low, with a high TSH, how should you adjust the dose of synthroid?
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increase dose
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If a pt's T4 is normal and TSH is normal/low how should you adjust synthroid dose?
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don't, leave it alone
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If a pt's T4 is high, and TSH is 'any" how should you adjust the pt's synthroid dose?
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decrease it
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Name 2 thyroid antagonists.
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methimazole (tapazole)
propylthiouracil (PTU) |
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What is MOA for thyroid antagonists?
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inhibits iodination of thyroxin precursors
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How does PTU inhibit iodinization of thyroxin precursors by....
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blocking conversion of t4 to t3 peripherally
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What are common s/e of thyroid antagonists?
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a granulocytosis
rash hypothyroidism |
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There is a delay in the onset of thyroid antagonists due to the long 1/2 life of __?
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T4
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While waiting for thyroid antagonists to take effect, how can you treat tachycardia?
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with beta-blockers
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If a pt's T4 is too high, how long should you hold their dose of thyroid before restarting at a lower dose?
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7 days
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Radioactive iodine I-131 is specific to the __?
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thyroid
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I-131 is the next step in ___therapy
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non-surgical
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Definition: excess renal elimination of free water; central lack of ADH, peripheral/renal fcnal loss of ADH activity....is ?
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diabetes insipidous
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there are 2 types of DI, what are they and which one is harder to treat?
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central DI
nephrogenic Di-harder to tx |
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A lack of ADH is which type of DI?
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central
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functional loss of ADH activity is which type of DI?
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peripheral/renal (nephrogenic)
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Name 2 drugs that can cause DI
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lithium
demeclocycline |
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Diabetes Insipiduous causes what to happen with a pt's sodium
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to decrease
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What is the treatment of central diabetes insipidous? what medication?
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DDAVP in either pill or nasal spray. is a ADH analog
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What can too much DDAVP cause?
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h20 retention, hyperhydration, and low sodium
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what other therapy can be introduced in DI?
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free water supplementation, becareful of the h2o and Na balance.
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excessive antidiuretic hormone is also called?
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SIADH
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What are some medication causes of SIADH?
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tegretol, ssri, diuretics,
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what medication can be used in the tx of SIADH?
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demeclocycline (declomycin) it antagonizes ADH in the kidney
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what other therapy can be used in the tx of SIADH?
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retriction of free water and sodium. often h2o restriction doesn't work as pt's are non-compliant.
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T/F
low thyroid cannot cause diabetes mellitus |
false, it can cause it
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every diabetic deserves consideration for treatment with what 3 medications?
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asa
ace inhibitor or arb statin |
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what are some complications of diabetes mellitus?
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#1 blindness
#2 neuropathy #3 retinopathy |
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why is diabetic neuropathy dangerous?
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pt's cannot feel their feet, or the ulcers they are developing
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