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57 Cards in this Set

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  • Back
Labetalol
Nonselective alpha and beta antagonist
Carvedilol
Nonselective alpha and beta antagonist
Phenoxybenzamine
Nonselective alpha antagonist
Phentolamine
Nonselective alpha antagonist
Prazosin
Alpha1 antagonist
Terazosin
Alpha1 antagonist
Doxazosin
Alpha1 antagonist
Indoramin
Alpha1 antagonist
Rauwolscine
Alpha2 antagonist
Yohimbine
Alpha2 antagonist
Tolazoline
Alpha2 antagonist
Propranolol
Nonselective beta antagonist
Pindolol
Nonselective beta antagonist
Timolol
Nonselective beta antagonist
Penbutolol
Nonselective beta antagonist
Nadolol
Nonselective beta antagonist
Carteolol
Nonselecive beta antagonist
Sotalol
Nonselective beta antagonist
Acebutolol
Beta1 antagonist
Betaxolol
Beta1 antagonist
Esmolol
Beta1 antagonist
Atenolol
Beta1 antagonist
Celiprolol
Beta1 antagonist
Metoprolol
Beta1 antagonist
Butoxamine
Beta2 antagonist
Isoproterenol
Nonselective beta agonist
Xamoterol
Beta1 agonist
Metaproterenol
Beta2 agonist
Fenoterol
Beta2 agonist
Terbutaline
Beta2 agonist
Salbutamol
Beta2 agonist
Ritodrine
Beta2 agonist
Salmeterol
Beta2 agonist
Formoterol
Beta2 agonist
Pirbuterol
Beta2 agonist
Bitolterol
Beta2 agonist
BRL 37344
Beta3 agonist
Oxymetazoline
Nonselective alpha agonist
Xylometazoline
Nonselective alpha agonist
Tetrahydrozoline
Nonselective alpha agonist
Phenylephrine
Alpha1 agonist
Metaraminol
Alpha1 agonist
Methoxamine
Alpha1 agonist
Clonidine
Alpha2 agonist
Guanabenz
Alpha2 agonist
Guanfacine
Alpha2 agonist
Rilmenidine
Alpha2 agonist
Moxonidine
Alpha2 agonist
Alpha-methyldopa
Alpha2 agonist
Propanolol
Nonselective B1 and B2 blocker
Large first pass effect
T 1/2 = 3-5 hr
Some CNS effects
First used as antiarrhythmic agent
Metoprolol
B1 50-100 > B2
T1/2 = 3-5 hr
Fewer side effects
Decreases renin release
Nadolol
Nonselective B1 and B2 blocker
Not readily metabolized
T1/2 = 14-24 hr
Once daily dosing is possible
No significant CNS effect
Timolol
Nonselective B1 and B2 blocker
Pindolol
Nonselective B1 and B2 blocker with intrinsic sympathomimetic activity (ISA) (partial agonist) Leads to less beta receptor up-regulation and less supersensitivity
Labetolol
Nonselective B1 and B2 plus a1 blocker
Beta:alpha block is 3:1
Beta blockade occurs at lower doses
Alpha plus beta blockade is good for treatment of pheochromocytoma
Carvediolol
S(-) isomer or racemic mixture exhibits non-selective beta blockade while the R(+) exhibits alpha blockade.
Bisoprolol
Selective B1 blocker
B1 selectivity is not absolute so that B2 activity occurs at doses above 20 mg.