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22 Cards in this Set
- Front
- Back
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What is the formula for CO and BP?
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CO = SV x HR
BP = CO x TPR |
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What is the effect of Beta 1 receptor agonists on the myocardium?
What is the effect of Alpha 1 receptor agonists on the vasculature? |
- Increased chronotropy (HR)
- Increased Inotropy (Contractility) - Increased Dromotropy (Velocity) - Increased velocity and contractility increase SV and HR is increased as well and therefore CO increases - Beta 1 receptors increase BP via CO - Alpha 1 receptors increase BP via TPR - Beta 2 receptors decrease BP via TPR |
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What are the two major roles of adrenoceptors on the eye?
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To regulate pupil size
Control aqueous humor production |
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What is the effect of Alpha 1 agonists on the eye?
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- Cause contraction of the Radial Dilator muscle and mydriais (pupil dilation)
- Cause vasoconstriction of Ciliary blood vessels and decreased aqueous humor production |
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What is the effect of Alpha 2 agonists on the eye?
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- Act on the Ciliary body to decrease aqueous humor production
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What is the effect of Beta 2 agonists on the eye?
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- Act on the Ciliary body to increase aqueous humor production
- Relax Ciliary body for far vision |
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What is the effect of Alpha 1 agonists on the Respiratory Tract?
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- Decrease mucosal secretions of the upper respiratory tract, decongest airways
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What is the effect of Beta 2 agonists on the Respiratory Tract?
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- Bronchiole smooth muscle dilation, facilitate air intake and gas exchange
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What is the effect of Alpha 2 agonists on the GI tract?
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- Decrease Peristalsis (indirectly via neurotransmitters, neuromodulators)
- Decrease Secretions |
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What is the effect of Beta 2 agonists on the GI tract?
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- Decreased Peristalsis (directly via smooth muscle receptors)
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What is the effect of Alpha 1 agonists on the Bladder?
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- Stimulation of Trigone and contraction of sphincter
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What is the effect of Beta 2 receptors on the Bladder?
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- Detrusor muscle relaxation
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What is the effect of Alpha 1 receptor agonists on the Prostate Gland?
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- Induce contraction of the prostate
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What is the effect of Alpha 1 agonists on Erectile Tissue?
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- Ejaculation via stimulation of receptors on the Vas Deferens, Seminal Vesicles, and Prostate
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What is the effect of Alpha 1 agonists on the Uterus?
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- Pregnant contraction
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What is the effect of Beta 2 agonists on the Uterus?
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- Relaxation
- Non-pregnant relaxation |
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Describe the sympathetic effect on the sweat glands.
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Psychologic stress causes stimulation of apocrine glands on the palms of the hands.
Thermoregulatory eccrine sweat glands are diffusely distributed and have muscarinic receptors that are innverated by sympathetic cholinergic post-ganglionic nerves. |
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What type of receptors stimulate insulin secretion?
Inhibit insulin secretion? |
Beta receptors
Alpha 2 receptors |
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What receptor type stimulates renin secretion of the kidney?
Inhibits renin secretion? |
Beta 1
Alpha 2 |
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What two receptor types enhance lipolysis in fat cells?
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Beta 3
Alpha 2 |
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What receptor type activates glycogenolysis?
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Beta receptors
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What can be a consequence of sympathomimetic high doses?
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Metabolic acidosis
Depletion of extracellular potassium |
