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8 Cards in this Set
- Front
- Back
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Haloperidol
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D2 Blocker
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Amisulpiride
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Dose related presynaptic D4 receptors (less than 300mg / day) and post synaptic D2 receptors (more than 300mg / day)
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Risperidone
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5HT2/D2 antagonist + Alpha-1 blockade (first dose hypotensive effect). High prolactin elevation due to D2 blockade
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Olanzapine
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5HT2/D2 antagonist + H1 blockade (sedative effect)
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Quetiapine
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5HT2/D2 Antagonist + H1 blockade (sedative effect) +Alpha 1 and Alpha 2 blockade (Hypotensive effect)
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Ziprasidone
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5HT2/D2 Antagonist and agonist activity at 5HT1A with monoamine reuptake inhibition. Less weight gain and metabolic syndrome due to the agonist activity and increased noradrenaline.
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Aripiprazole
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Partial agonist at D2 receptors and partial agonist at 5HT1A receptors
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Paliperidone
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D2 and 5HT2A antagonist. Does not undergo hepatic metabolism.
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