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22 Cards in this Set

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  • Back
Nitrates

nitroglycerin (nitrostat)
isosorbide dinitrate (Isordil)
erythrityl tetranitrate (Tetranitrol)
decrease ischemia through smooth muscle relaxation of preload and afterload
decrease preload through peripheral vasodilation
reduce myocardial oxygen demand
reduce chest discomfort (angina)
may also dilate coronary arteries
improve coronary blood flow

Most Common Side Effects:
Nitroglycerin, Isosorbide Dinitrate - Dizziness, lightheadedness, or fainting when sitting up or standing; flushing of face and neck; headache; irritation at the injection site; nausea; vomiting.
.
Beta-adrenergic blocking agents

Propranolol (Inderal)
Bisoprolol (Zebeta)
Atenolol (Tenormin)
Metoprolol (Lopressor)
Decrease heart's oxygen demand through decreasing HR and contractility. Treat angina, arrhythmias, HTN.

Most Common Side Effects:
Propranolol - Constipation; diarrhea; dizziness; drowsiness; fatigue; lightheadedness; mild pain, swelling, or redness at the injection site; nausea; stomach upset or cramping; trouble sleeping; vomiting; weakness.
Bisoprolol -Diarrhea; dizziness; drowsiness; fatigue; headache; lightheadedness; nausea; sleeplessness; unusual tiredness; weakness.
Atenolol -Cold fingers or toes; diarrhea; dizziness; drowsiness; headache; lack of energy; lightheadedness; nausea; tiredness.
Metoprolol -Constipation, cough; diarrhea; dizziness; drowsiness; dry mouth or eyes, headache; lightheadedness; mild fatigue; mild flu symptoms (eg, chills, fever, sore throat); nausea; tiredness; vomiting.
Calcium channel blocking agents

Diltiazem (Cardizem)
Amlodipine (Norvasc)
Nifedipine (Procardia XL)
Verapamil (Calan)
decreases heart's oxygen demand by reducing the flow of Ca+. Allows for peripheral vasodilation that further reduces demand on the heart (i.e., dilate coronary arteries, reduce BP, contol arrhythmias, angina).

Most Common Side Effects:
Diltiazem -Constipation; dizziness; facial flushing; headache; lightheadedness; tiredness; weakness.
Amlodipine - Dizziness; headache; persistent, dry cough.
Nifedipine -Constipation; dizziness; flushing; giddiness; headache; heat sensation; heartburn; lightheadedness; nausea; weakness.
Verapamil - Dizziness; fatigue; headache; lightheadedness; mild pain, redness, or swelling at the injection site.
Antiarrhythmics

Lidocaine (Xylocaine)
Amiodarone (Cordarone)
Bretylium tosylate
Procainamide (Procanbid)
alter conductivity in order to correct ectopic stimuli or other electrical abnormality

Most Common Side Effects:
Lidocaine (Xylocaine) - Irritation; numbness; redness.
Amiodarone (Cordarone) - Abnormal skin sensations (loss of sensation; tingling; numbness; prickling); bitter taste in mouth; blue-green discoloring of skin (especially hands or feet); constipation; decreased sexual interest; dizziness; dry eyes; flushing of the face; general body discomfort; headache; involuntary muscle movements; loss of appetite; nausea; poor coordination; tiredness; trouble sleeping; vomiting.
Bretylium tosylate
Procainamide (Procanbid) - Pain, swelling, or redness at the injection site.
Antihypertensives
control HTN
goal to maintain a diastolic pressure <90mm Hg
decrease afterload
reduce myocardial O2 demaind
Nitrates

nitroglycerin (nitrostate)
isosorbide dinitrate (Isordil)
erythrityl tetranitrate (Tetranitrol)
decrease ischemia through smooth muscle relaxation of preload and afterload
decrease preload through peripheral vasodilation
reduce myocardial oxygen demand
reduce chest discomfort (angina)
may also dilate coronary arteries
improve coronary blood flow
Beta-adrenergic blocking agents

Propranolol (Inderal)
Bisoprolol (Zebeta)
Atenolol (Tenormin)
Metoprolol (Lopressor)
Decrease heart's oxygen demand through decreasing HR and contractility. Treat angina, arrhythmias, HTN.
Calcium channel blocking agents

Diltiazem (Cardizem)
Amlodipine (Norvasc)
Nifedipine (Procardia XL)
Verapamil (Calan)
decreases heart's oxygen demand by reducing the flow of Ca+. Allows for peripheral vasodilation that further reduces demand on the heart (i.e., dilate coronary arteries, reduce BP, contol arrhythmias, angina).
Antiarrhythmics

Lidocaine (Xylocaine)
Amiodarone (Cordarone)
Bretylium tosylate
Procainamide (Procanbid)
alter conductivity in order to correct ectopic stimuli or other electrical abnormality
Antihypertensives
control HTN
goal to maintain a diastolic pressure <90mm Hg
decrease afterload
reduce myocardial O2 demaind
Digitalis (cardiac glycosides)
increases contractility
decreases heart rate
mainstay in tx of CHF (digoxin)

Most Common Side Effects: Diarrhea; nausea.
Diuretics
Furosemide (Lasix)
Hydrocholorthiazide (Esidrix, Microzide, Hydrodiuril)
Chlorthalidone (Thalitone, Hygroton)
Spriondactone (Aldactone)
Amiloride (Midamor)
increase sodium and wagter excretion to manage HTN, CHFdecrease myocardial work (reduce preload and afterload)
control HTN (furosemide/Lasix; hydrocholorthiazide/Esidrix)

Most Common Side Effects: increased urination
may also have too much potassium in their blood (hyperkalemia) if they take a potassium-sparing diuretic, or too little potassium in their blood (hypokalemia) if they take a thiazide diuretic.
Aspirin
decreases platelet aggregation
may prevent MI

Most Common Side Effects: Heartburn; nausea; upset stomach
Tranquilizers
decrease anxiety
sympathetic effects
Hypolipidemic agents
(6 major cholesterol lowering drugs)
cholestyramine (Questran)
colestipol (Colestid)
simvastatin (Zocor)
lovastatin (Mevacor)
reduce serum lipid levels when diet and weight reduction are not effective

Most Common Side Effects: Simvastatin:Back pain; constipation; diarrhea; flushing (eg, dizziness, itching, redness, tingling, warmth); headache; nausea; runny or stuffy nose; stomach upset.
Lovastatin, cholestyramine: Constipation
Colestipol: Bloating; constipation; diarrhea; gas; heartburn; indigestion; loose stools; nausea; stomach pain or cramping; vomiting.
Alpha-adrenergic Blocking Agents
Prazosin (Minipress)
Terazosin (Hytrin)
Doxazosin (Cardura)
block post-synaptic alpha 1-adrenergic receptors which dilates arterioles and veins
decreases BP

Most Common Side Effects: Prazosin - Dizziness; drowsiness; dry mouth; frequent urination; headache; lack of energy; lightheadedness; nasal congestion; nausea; weakness. Terazosin, Doxazosin - Dizziness; drowsiness; lightheadedness; nasal congestion; nausea; weakness.
Angiotensin-converting Enzyme Inhibitor (ACE) Agents
Captopril (Capoten)
Enalapril (Vasotec)
Lisinopril (Prinivil)
Fosinopril (Monopril)
Benazepril (Lotenson)
Remipril (Altace)
decrease BP and afterload in pts with CHF and HTN

Most Common Side Effects:
Captopril - Cough; diarrhea; dizziness or lightheadedness when sitting or standing quickly; fatigue; fever; headache; itching; joint pain; nausea; taste changes; vomiting; weakness. Enalapril - Diarrhea; dizziness or lightheadedness when sitting up or standing; headache; nausea; persistent, dry cough; tiredness; vomiting. Lisinopril - Cough; diarrhea; dizziness; headache; tiredness. Fosinopril - Dizziness or lightheadedness when sitting up or standing; dry cough
Angiotensin II Receptor Antagonist Agents
Losartan (Cozaar)
Diltiazem (Cardizem)
Verapamil (Calan)
decrease BP and afterload in pts with CHF and HTN

use these when pts cannot tolerate ACE inhibitors

Most Common Side Effects:
Losartan - Diarrhea; dizziness; tiredness. Diltiazem - Constipation; dizziness; facial flushing; headache; lightheadedness; tiredness; weakness. Verapamil -Dizziness; fatigue; headache; lightheadedness; mild pain, redness, or swelling at the injection site.
Bronchodilator Agents

anticholinergic
beta-adrenergic
methylxanthine
relieve bronchospasm
increase size of airway and reduce restistnace and subsequent obstruction

Common Side Effects:
albuterol - Dizziness; headache; nausea; nervousness; sinus inflammation; sore or dry throat; tremor; trouble sleeping; vomiting.
Inhaled Corticosteroid Agents

Beclomethasone (Vanceril)
Budesonide (Pulmicort)
Fluticasone propionate (Flovent)
Dexamethasone (Decadron)
control inflammation of airway
decrease bronchospasm
stabilize inflammatory resposne in the respiratory tract
Mucolytic Agents

Acetylcysteine (Mucosil)
Dornase alpha (Pulmozyme)
Thin mucous secretions by alterting composition and consistency of mucus
Antiasthmatic Agents

Cromolyn sodium (Intal)
Nedocromil sodium (Tilade)
stabilize mast cells;
inhibit release of inflammatory medications