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10 Cards in this Set
- Front
- Back
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Anti-Angina Drug Classes (4)?
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Nitrates
Ca+2 Channel Blockers β Blockers Vasodilators |
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Name some Nitrate drugs?
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Amyl nitrate
Nitroglycerin Isosorbide dinitrite |
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Nitrate uses?
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ANGINA, pulmonary edema, heart failure
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Nitrate MOA?
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convert to NO -> activated guanylate cyclase -> increase cGMP, dephosphorylation of myosin light chain, vasodilation
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Nitrate side effects?
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headache, reflex tachycardia, orthostatic HTN
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Nitrate administration?
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sublingual, IV, patches
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Name some Calcium Channel blockers?
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Verapamil
Diltiazem Nifedipine nicardipine amlodipine |
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Calcium channel blocker uses?
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angina, supraventricular arrythmias, hypertension
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Calcium channel blockers MOA?
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reduce intracellular Ca+2 -> smooth muscle relaxation, decreased contractility
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Calcium channel blockers side effects?
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bradycardia, hypotension, headache, flushing, peripheral edema
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