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35 Cards in this Set
- Front
- Back
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nursing intervention for antineoplastic agent in general and with doxorubicin
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-blood test to monitor bone marrow function
-monitor cardiac and respiratory fx as well clotting times -protect exposure inf -keep pt hydrated -small frequent meals -proper head covering |
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management nausea and vomiting with antineoplastic agents
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-give antiemetic agent prior treatment
-make sure environment accepting -mouth care ice chips -antihistamines to decrease secretions -corticosteroids: relieve inflammation -keep pt hydrated |
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stages drug development
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preclinical- tested animals
phase 1- human volunteers phase 2 - pts that have disease phase 3- vast clinical market phase 4- continual evaluation |
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safety of OTC drugs
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take as prescribed
-tell what OTC's your taking -may mask s & s of disease |
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how drug affects body
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replace or act as substitutes
-increase or stimulate certain cell activities -to depress or slow cellular activities - to interfere with fxing of foreign cell |
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receptor theory
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agonist interaction- binds to receptor site and produces effect
-competitive agonist- drug blocks site so others can't bind -noncompetitive antagonism - attaches to different site, but still prevents other drug to bind |
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half life calculation
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time it takes for the amount of drug in body to decrease to one half of the peak level it once achieved
-20 mg half life two hours: 10 mg remain 2 hours: 5 remain 4 hours |
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adult dosage
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based on 150 lb person
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interactions with herbal supplements
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st johns wort interact with oral contraceptives, digoxin, SSRI, theophylline, antineoplastic, antiviral
-with PROZAC serious side effects and toxic reactions |
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rights med admin
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drug, storage, route, dose, prep, time, recording
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childs dose
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based on wt, age, or BSA
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pt teaching for anti-infective agent
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only use drug for infection its prescribed for
-take as prescribed full number of days and dose |
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culture and sensitivity
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should be done before anti-infective agent given
-if inf serious drug given before organism identified |
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bacteriostatic
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prevents growth bacteria
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most serious side effect antimicrobial drug
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toxic effect kidneys
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bacteriocidal
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kills bacteria directly
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broad spectrum
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affects many organisms
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narrow spectrum
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affects specific organisms
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broad spectrum anti-infective meds
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interfere with biochem reactions in many dif kinds of microorg
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Iv meds for CMV
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foscarnet (foscavir)
cidofovir (vistide) |
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entecavir
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don't run out of drug
-use barrier contraceptives -no breastfeeding |
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aralen
(chloroquine) |
take safety precautions
-change position slowly -avoid driving and hazardous tasks -take drug with meals -report blurring of vision, loss hearing |
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metronidazole
(flagyl) |
shouldn't be combined with alcohol three days after treatment
-take with small meal |
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anthelmentic agent
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safety precaution
-take small meal -importance of strict handwashing and hygiene -daily laundering |
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assessment prior to administering systemic antifungal agent
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history allergy to antifungal
-history of liver or renal dysfunction -do not give if preg or breastfeeding -physical assessment to get baseline -collect data -culture of infected area |
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amphotercin B
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can be used during preg not lactation
-available IV form ONLY -may take 6 months of treatment -monitor Iv site, renal and hepatic level |
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vancomycin
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-not faster than one hour
-dont give if trough over 20 -cause red man syndrome -reserved for very special situation |
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interaction for FLUCONAZOLE
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avoid with
cyclosporine digoxin oral hypoglycemic warfarin oral anticoagulant phenytoin |
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assessment for pt with protozoal inf
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don't give if preg or lactating
-dont give with CNS disease -cadidiasis can become severe |
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antimalarials
adverse effect |
headache pruitis
dizzy hepatic dysfx fever visual ch shaking ototoxicity chills malaise n/v rash |
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mebendazole
adverse effect |
abdominal discomfort
diarrhea pain don't give childen under 2 |
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aminoglycosides
adverse effect |
black box warning
risk ototoxicity nephrotoxicity confusion depression numbness tingling bone marrow depression GI effect cardiac effects |
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carbapenems
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toxic effect on GI tract
superinfection CNS effects headache dizzy altered mental status |
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mebendazole
(Vermox) |
prototype drug to treat pinworm
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peak and trough level
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trough is the lowest drug level thats needed to reach therapeutic range (draw 30 mins before)
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