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38 Cards in this Set
- Front
- Back
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Direct sympathomimetic |
Epinephrine, Norepinephrine, Isoproterenol, Dopamine, Dobutamine, Phenylephrine, Metaproterenol. |
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Indirect sympathomimetic |
Amphetamine, Ephedrine, Cocaine |
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Sympathoplegics |
Clonidine, Alfa Methyl Dopa |
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Epinephrine. Effects & applications |
a1, a2, b1, b2(weak). anaphylaxis, glaucoma, asthma, hypotension |
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Norephinephrine. Effects & applications |
a1, a2, b1(weak) hypotension |
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Isoproterenol |
b1, b2 AV block |
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Dopamine |
Low dose : D1 Medium dose : b1,b2 High dose : a1, a2 Shock, heart failure D1 : inotropic & chronotropic positive |
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Dobutamine |
a1 = a2 = b2 (weak), b1 Heart failure, cardiac stress testing, inotropic |
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phenylephrine |
a1, a2(weak) Nasal decongestant, pupillary dilation, vasoconstriction |
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Metaproterenole & Albuterol |
b1(weak), b2 Acute Asthma |
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Salmeterol |
Asthma long term treatment |
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Terbutaline |
Reduce premature uterine contraction |
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Ritodrine |
b2 Reduce premature uterine contraction |
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Indirect sympathomimetics effect |
Indirect general agonist, releases stored cathecolamines, uptake inhibitor |
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Amphetamine |
Narcolepsy, obesity, ADD |
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Ephedrine |
Nasal decongestant, hypotension, urinary incontinence |
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Cocaine |
Vasoconstriction, Local anesthesia |
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Clonidine & a methyl dopa. Action & applications |
a2 agonist, decrease central adrenergic outflow. Hypertension in renal disease (no decrease blood flow in kidney) |
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Alpha blocker non selective |
Phenoxybenzamine, Phentolamine |
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Phenoxybenzamine |
Irreversible Use : Pheocromocytoma (before removing tumor) |
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Phentolamine |
Reversible Patient with MAO inhibitor who eat tyramine |
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Toxicity phenoxybenzamine & phentolamine |
Orthostatic hypertension reflex tachycardia |
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Alpha 1 blocker selective |
"ozin" endings. Prazosin, terazosin, doxazosin. Use : Hypertension, urinary retension in BPH. |
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Alpha 1 blocker selective toxicity |
orthostatic hypertension, dizziness, headache |
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Alpha 2 blocker selective |
Mirtazapine use : Depression Toxicity : Sedation, inc serum cholesterol, inc appetite |
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Beta 1 blocker selective |
Acetabutolol, esmolol, betaxolol, atenolol, metoprolol |
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Beta blocker non selective |
Propanolol, Timolol, Nadolol, Pindolol |
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Partial beta agonist |
acebutolol, pindolol |
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Non selective alpha & beta blocker |
Carvedilol, labetalol |
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B1 blocker selective |
Patients with comorbid pulmonary disease |
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Beta blocker toxicity |
impotence, exacerbation of asthma, CV adverse effect (CHF, bradycardi, AV block), CNS adverse effect (sedation, sleep alterations) |
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Beta blocker application |
Hypertension, angina pectoris, MI, SVT (esmolol, propanolol), CHF, glaucoma (timolol) |
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Beta blocker effect on hypertension |
decrease cardiac output and renin secretion (beta receptor blockade on JGA cells) |
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Beta blocker effect on angina pectoris |
decrease heart rate & contractility, resulting in decrease oxygen consumption |
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Beta blocker effect on MI |
decrease mortality |
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Beta blocker effect on SVT (esmolol, propanolol) |
decrease AV conduction velocity (class II antiarrythmic) |
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Beta blocker effect on CHF |
slow progression of chronic failure |
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Beta blocker effect on glaucoma (timolol) |
decrease secretion of aqueous humor |
