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25 Cards in this Set
- Front
- Back
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Levodopa
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Uses: Parkinsons
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Carbidopa
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Mech: inhibitor of DOPA decarboxylase
Uses: coadministered with l-dopa for parkinsons |
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Bromocriptine
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Mech: D2 agonist
Uses: adjuvants to l-dopa treatments |
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Pergolide
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Mech: D1 and D2 agonist
Uses: adjuvants to l-dopa treatments |
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Pramipexole
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Mech: D3> D2 agonist
Uses: adjuvants to l-dopa treatments |
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Ropinerol
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Mech: D3> D2 agonist
Uses: adjuvants to l-dopa treatments |
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Entacapone
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Mech: inhibit COMT --> inhibit DA degredation
Uses: Parkinsons |
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Selegiline
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Mech: MAO inhibitor (low doses: selective for MAO_B)
Uses: Parkinsons |
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Chlorpromazine
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Mech: typical antipsychotis
Uses: Parkinsons |
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Haloperidol
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Mech: deconaoate esters--> long acting
Uses: antipsychotic agent |
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Amitriptiline
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Mech: inhibit NET reuptake of NE
Uses: TCA |
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Fluoxetine
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Mech: SSRI
Uses: major depressive disorder, anxiety disorder |
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Bupropion
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Mech: atypical antidepressants
acts lke amphetamines Uses: antidepressant |
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Pargyline
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Mech: MAO_B inhibitor
Notes: can cause hypertensive crisis (cheese, wine) |
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Tranylcypromine
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Mech: non-selective MAO inhibitor
Uses: antidepressant |
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Lithium
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Mech: mimics small nmonovalent cations --> disrupts transproters that requrie specific cation cofactors
Uses: bipolar disorder |
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Midazolam
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Mech: blocks 5HT, a2-adrenergic receptor, decreases neurotransmission at 5HT2 receptors, increase NE neurotransmission
Uses: depression |
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Diazepam
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Mech: benzodiazepine
Uses: anxiety disorder, status epilepticus, muscle relaxanta, IV genearl anesthetic, alcohol withdrawl |
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Flumazenil
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Mech: GABA_A receptor antagonist
Uses: treatment/diagnosis of benzodiazepine overdose |
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Phenytoin
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Mech: enhance Na channel inhibition by slowing Na channel recovery from inactive state
Uses: Partial, tonic-clonic seizures |
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Fosphenytoin
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Mech: water soluble phenytoin pro-drug
Uses: seizures |
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Carbamazepine
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Mech: enhance Na channel inhibition by slowing Na channel recovery from inactive state
Uses: Partial, tonic-clonic seizures |
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Phenobarbital
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Mech: barbiturate
Uses: generalized tonic-clonic and partial seziures |
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Primidone
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Mech: GABA receptor agonist (active metabolites: phenobarbitol and PEMA)
Uses: anticonvulsant |
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Valproic Acid
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Mech: reduce activity of low threshold T-type calcium channel
Uses: Tonic-clonic, absence, atypicla absense, partial seziures |
