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25 Cards in this Set

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Levodopa
Uses: Parkinsons
Carbidopa
Mech: inhibitor of DOPA decarboxylase
Uses: coadministered with l-dopa for parkinsons
Bromocriptine
Mech: D2 agonist
Uses: adjuvants to l-dopa treatments
Pergolide
Mech: D1 and D2 agonist
Uses: adjuvants to l-dopa treatments
Pramipexole
Mech: D3> D2 agonist
Uses: adjuvants to l-dopa treatments
Ropinerol
Mech: D3> D2 agonist
Uses: adjuvants to l-dopa treatments
Entacapone
Mech: inhibit COMT --> inhibit DA degredation
Uses: Parkinsons
Selegiline
Mech: MAO inhibitor (low doses: selective for MAO_B)
Uses: Parkinsons
Chlorpromazine
Mech: typical antipsychotis
Uses: Parkinsons
Haloperidol
Mech: deconaoate esters--> long acting
Uses: antipsychotic agent
Amitriptiline
Mech: inhibit NET reuptake of NE
Uses: TCA
Fluoxetine
Mech: SSRI
Uses: major depressive disorder, anxiety disorder
Bupropion
Mech: atypical antidepressants
acts lke amphetamines
Uses: antidepressant
Pargyline
Mech: MAO_B inhibitor
Notes: can cause hypertensive crisis (cheese, wine)
Tranylcypromine
Mech: non-selective MAO inhibitor
Uses: antidepressant
Lithium
Mech: mimics small nmonovalent cations --> disrupts transproters that requrie specific cation cofactors
Uses: bipolar disorder
Midazolam
Mech: blocks 5HT, a2-adrenergic receptor, decreases neurotransmission at 5HT2 receptors, increase NE neurotransmission
Uses: depression
Diazepam
Mech: benzodiazepine
Uses: anxiety disorder, status epilepticus, muscle relaxanta, IV genearl anesthetic, alcohol withdrawl
Flumazenil
Mech: GABA_A receptor antagonist
Uses: treatment/diagnosis of benzodiazepine overdose
Phenytoin
Mech: enhance Na channel inhibition by slowing Na channel recovery from inactive state
Uses: Partial, tonic-clonic seizures
Fosphenytoin
Mech: water soluble phenytoin pro-drug
Uses: seizures
Carbamazepine
Mech: enhance Na channel inhibition by slowing Na channel recovery from inactive state
Uses: Partial, tonic-clonic seizures
Phenobarbital
Mech: barbiturate
Uses: generalized tonic-clonic and partial seziures
Primidone
Mech: GABA receptor agonist (active metabolites: phenobarbitol and PEMA)
Uses: anticonvulsant
Valproic Acid
Mech: reduce activity of low threshold T-type calcium channel
Uses: Tonic-clonic, absence, atypicla absense, partial seziures