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62 Cards in this Set
- Front
- Back
Natural penicillin is the safest drug as far as toxicity is concerned, EXCEPT for its ability to
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evoke seizures in meningitis and epilepsy and cause hypersensitivity reactions
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Co-trimoxazole is a combination of
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sulfametoxazole and trimethoprim
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Entero-hepatic cycling is the property of
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erythromycin
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All of the following penicillins are resistant to penicillinase EXCEPT
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ampicillin
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Niclosamide is a drug used in the treatment of
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flatworm infestation
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Kernicterus may be evoked in newborn or premature children treated with sulfonamides because of
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displacement of bound bilirubin from albumin
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Drugs used in the prophylaxis and treatment of malaria include all of the following EXCEPT
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sulfametoxazole-trimetoprime
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A drug of choice in treatment of clindamycin-induced pseudomembranaceus colitis is
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vancomycin
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Clavulanic acid is an important ageant in the treatment of bacterial infections because
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it inactivates bacterial beta-lactamase
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Doxorubicin (a)
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damages the myocardium
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Dapsone (b)
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used in treatment of leprosy
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Bleomycin (c)
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damages the lungs
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Griseofulvin (d)
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disrupts mitotic spindle
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Methotrexate is the anticancer agent acting by
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interference with folic acid related purine nucleotide synthesis
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Emetine is a drug used in treatment of
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amebiasis
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Which of the following agents is used in the treatment of systemic mycosis
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amphotericin B
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Amantadine is a drug used in the treatment of
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Parkinson
viral respiratory infections |
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Trimethoprim is a drug that
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inhibits dihydrofolate reductase
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Of the following statements about mechlorethamine select one that is INCORRECT
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it is the most lipophilic agent and excellently penetrates the brain
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All of the following statements about 5-Fluorouracil are true EXCEPT
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it is a purine analogue (it's a pyrimidine analogue)
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In case you cannot use penicillins for treatment, you may substitute them with
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macrolides (erythromycin)
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Sulfadiazine (a)
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inhibits folate production
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Cephalothin (b)
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inhibits cell wall synthesis
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Amphotericin (c)
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binds to ergosterol
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Gentamycin (d)
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binds to the 30S subunit
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Anticancer drugs that are useful in the treatment of the following diseases other than neoplasms include all of the following EXCEPT
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alopecia
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Vincristine (a)
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Hodgkin's disease
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Estrogens (b)
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prostatic carcinoma
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Cyclophosphamide (c)
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Burkitt's lymphoma
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Methotrexate (d)
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Chorioncarcinoma
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Metronidazole is an agent useful in the therapy of
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infections with anaerobic bacteria and Trichomonas vaginalis
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Leucovorin is an agent used for
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rescue in the course of therapy with methotrexate
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Fluoroquinolones (norfloxacin, ciprofloxacin) have the following adverse effects
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CNS problems
cartilage toxicity in children blood discrasias |
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A possible treatment for M. pneumonia will be
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erythromycin
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Adverse reactions of isoniazid include all of the following EXCEPT
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alopecia
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All of the following statements about penicillin G are correct EXCEPT
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can be given orally
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All of the following statements regarding tetracyclins are true EXCEPT
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they cause peripheral polyneuropathy
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Which of the following agents acts by depolarizing the neuromuscular junction
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pyrantel
succinylcholine |
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The most dangerous antibiotic as far as bone marrow toxicity is concerned is
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chloramphenicol
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Drug of choice for treatment of Legionella is
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erythromycin
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Vancomycin (a)
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bacterial agent used in the treatment of C. difficile evoked pseudomembranaceous colitis
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Azythromycin (b)
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a macrolide antibiotic with activity also against G(-)-bacteria
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Benzathine penicilline (c)
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has a prolonged action - given once a week
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Acyclovir (d)
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used in hepatic infections, derivative of guanine
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All of the following statements about fluocytosine are correct EXCEPT
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it is an anticancer drug
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Vincristine and vinblastine act through
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disruption of the mitotic spindle
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In case of administration of which antibiotic the food accelerates its absorption from the gut?
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macrolides
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Dapsone (a)
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inhibits folate synthesis
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Quinolones (b)
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damages cartilages and bones in children
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Isoniazide (c)
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inhibits mycolic acid synthesis
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Rifampin (d)
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causes orange discoloration of urine, mucus, saliva, sweat and tears
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Which of the following sulfonamides has the longest half-life?
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sulfamethoxasole
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All of the following statements about imipenem are true EXCEPT
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it is adminsitered in combination with cisplatin
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The drug of choice in treatment of early stages of Lyme disease is
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doxocycline
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All of the following statements about acyclovir are true EXCEPT
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it is activated in infected cells
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Antibiotics of choice in pregnant women are
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penicillins
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The best drug to treat mastitis caused by opportunistic Staphylococcus from oral cavity of breastfed infants are
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amoxycillin+clavulanic acid
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Which of the following drugs is a drug of choice in treatment of anaerobic bacterial infections
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metronidazole+vancomycin
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Which of the following adverse reactions of chloramphenicol is specific for infants
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Grey syndrome (grey baby syndrome)
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Which of the drugs used in the treatment of AIDS is a protease inhibitor?
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saquanir
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Which of the following drugs are not used for the treatment of tuberculosis?
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griseofulvin
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Which of the following antibiotics can be administered for only 3-4 days with a full therapeutic action?
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azithromycin
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