Pharmacology Exam 3

Front 1

H2 antagonist used for?

Back 1

GERD or PUD

Front 2

H2 antagonist MOA

Back 2

block H2 receptors in parietal cells in stomach preventing acid (HCl)

Front 3

H2 antagonist side effects

Back 3

GI discomfort

confusion

drowsiness

Front 4

H2 antagonist examples

Back 4

Pepcid

Zantac

Front 5

Proton pump inhibitors used for?

Back 5

GERD

PUD

Front 6

Protein pump inhibitors MOA

Back 6

Inhibits acid production by stopping final steps in parietal cells

Front 7

Protein pump inhibitors side effects

Back 7

GI discomfort

Front 8

Protein pump inhibitors examples

Back 8

Prilosec

Prevacid

Protonix

Front 9

Anticholinergics used for?

Back 9

n/v

Front 10

Anticholinergic MOA

Back 10

Inhibits intestinal cramping and vestibular input

Front 11

Anticholinergic side effects

Back 11

dry mouth

Front 12

Anticholinergic examples

Back 12

scopolamine

Front 13

Carafate MOA

Back 13

coats surface of ulcer

Front 14

bulk forming laxatives MOA

Back 14

Absorb fluid and swell intestine by activating NaCl channels

Front 15

saline laxatives MOA

Back 15

draws water into intestines through osmosis

Front 16

stimulant laxative MOA

Back 16

produces irritation in intestines and promotes peristalsis

Front 17

Antacid MOA

Back 17

neutralizes HCl

Front 18

Antacid side effects

Back 18

diarrhea

constipation

nephrotoxic

Front 19

nonpharmalogical measures for vomiting

Back 19

tea, flat soda, IV fluids, crackers

Front 20

Dopamine receptor antagonist MOA

Back 20

blocks dopamine receptors in stomach and CTZ

Front 21

dopamine receptor antagonist examples

Back 21

Reglan

Front 22

tardive dyskinsia

Back 22

from long term use of CNS meds

Front 23

s/s of Parkinson's

Back 23

tremors, rigid muscles, slurred speech, slowed movement

Front 24

goal of parkinson's drug therapy

Back 24

manage s/s of disease

NOT cure

Front 25

Paxil classification

Back 25

SSRI

Front 26

Paxil MOA

Back 26

increases reuptake of serotonin

Front 27

Paxil side effects

Back 27

Insomnia

GI

tremors

decreased sex drive

Front 28

antipsychotics MOA

Back 28

block dopamine receptors

impulse transmission decreases

Front 29

benzodiazepines MOA

Back 29

potentiate GABA (reduce seizures)

Front 30

benzodiazepines examples

Back 30

diazepam, lorazepam (-zepams)

Front 31

Nardil MOA

Back 31

Removes monoamine oxidase by removing NE, serotonin, dopamine from brain

Front 32

Nardil side effects

Back 32

many: neurological, GI, other

not used as much because of many side effects

Front 33

hypothyroidism s/s

Back 33

cold skin, decreased metabolism, brittle hair, fatigue

Front 34

hyperthyroidism s/s

Back 34

increased metabolism, bug eyes, weight loss, fine hair

Front 35

lispro onset

Back 35

5-15 min

Front 36

lispro peak

Back 36

1-3 hrs

Front 37

lispro duration

Back 37

3-5 hrs

Front 38

lantus onset

Back 38

2 hrs

Front 39

lantus peak

Back 39

none

Front 40

lantus duration

Back 40

24 hrs

Front 41

sulfonylureas MOA

Back 41

stimulate release of preformed insulin from the pancreas

Front 42

sulfonylureas examples

Back 42

glipizide, glyburide (-ride)

Front 43

metformin MOA

Back 43

decreases production of glucose in liver

Front 44

metformin side effects

Back 44

hepatotoxic

Front 45

NSAIDs MOA

Back 45

Inhibits COX action

Front 46

NSAIDs examples

Back 46

ibruprofen, naproxen, celebrex

Front 47

Opioids MOA

Back 47

binds with opioid receptors in CNS to block pain response