Pharmacology Exam 2 Drug List

Front 1

Pilocarbine

Back 1

muscarinic agonist
Used topically on the eye to contract the iris. Opens canal of schlemm, increases outflow of aqueous. For glaucoma

Front 2

Bethanecol

Back 2

muscarinic agonist
increased ladder contraction and increased sphincter relaxation - helps you pee!
Parasympathetic side effects - bradycardia, hypotension, sweating, salivation, diarrhea.

Front 3

Carbachol

Back 3

muscarinic agonist
Topical eye drop for glaucoma. Contracts pupil, canal of schlemm opens. Aqueous humor leaves.

Front 4

Atropine

Back 4

Competetive muscarinic antagonist. Causes sedation and at high doses, psychosis. Can cause tachycardia and vasodilation. Sympathetic effects.
Used as an antidote for ACh inhibitor poisoning, emergency bradycardia

Front 5

Scopolamine

Back 5

competitive muscarinic antagonist. Derived from atropine. Sympathetic effects.
Prevents motion sickness.
Scopalamine - prevents you from scooping up vomit.

Front 6

Ipratropium

Back 6

blocks the muscarinic cholinergic receptors in the smooth muscles of the bronchi in the lungs. This opens the bronchi, and provides relief in chronic obstructive pulmonary disease and acute asthma. This is inhaled.

Front 7

Physostigmine

Back 7

anticholinesterase - can cross BBB. counteracts atropine. Can treat claugoma in eyedrop form.

Front 8

Neostigmine

Back 8

anticholinesterase
Treats myasthenia gravis, used to stimulate GI tract and bladder, and overcome non-depolarizing nm blockade. Does not cross BBB.

Front 9

pyridostigmine

Back 9

Anti-AChE - treats myasthenia gravis

Front 10

tubocurarine

Back 10

competetive inhibitor at NMJ

Front 11

succinylcholine

Back 11

depolarizing agent at NMJ

Front 12

pancuronium

Back 12

competetive inhibitor at NMJ

remember - cur - curare - nmj blocker

Front 13

Vecuronium

Back 13

competitive inhibitor at NMJ

Front 14

Norepinephrine

Back 14

alpha adrenergic agonist
Used as a pressor in emergency situations, shock.
Side effects - angina, MI, arrhythmias

Front 15

Phenylephrine

Back 15

Alpha1 agonist.
Treats severe hypotension and shock, nasal congestion, and pupil dilation.

Front 16

Methoxamine

Back 16

Alpha 1 agonist
Increases peripheral resistance
Reflex bradycardia

Front 17

metaraminol

Back 17

Alpha 1 agonist
Prevents hypotension in anesthesia situation

Front 18

tetrahydrozoline

Back 18

Alpha agonist - visine! Contracts blood vessels - gets the red out.

Front 19

clonidine

Back 19

Alpha 2 agonist - decreases norepinephrine release. Treatment for hypertension

Front 20

Phentolamine

Back 20

Short acting, reversible alpha antagonist Diagnoses pheochromocytoma.
PHEntolamine - PHEochromocytoma

Front 21

Phenoxybenzamine

Back 21

Irreversible alpha receptor antagonist.
Treatment of pheochromocytoma (too much adrenergic activity)
Phenoxy - pheochromo

Front 22

Prazosin

Back 22

Alpha 1 antgonist. Decreases blood pressure. Decreases prostatic and bladder neck contraction - helps you pee in BPH.
Praz-prostate.

Front 23

Isoproterenol

Back 23

Potent Beta agonist. Increases heart rate and contractility.
SE- tachyarrhythmias, anxiety, puonary edema

Front 24

Dobutamine

Back 24

B1>>B1 Agonist
Heart failure and cardiogenic shock. INcreases HR and contractility

Front 25

Albuterol

Back 25

INhaled B2 agonist - bronchodilator

Front 26

terbutaline

Back 26

B2 agonist - stops premature labor by relaxing the uterus, and bronchodilator for asthma.
Terbutaline - prevents turbulent flow of air thru lungs, turbulent delivery

Front 27

metaproterenol

Back 27

B2 agonist - asthma treatment

Front 28

Propanolol, nadolol, timolol

Back 28

Beta antagonist. HTN Tx.
Can cause bronchoconstriction

Front 29

metoprolol

Back 29

Beta1 antagonist - decreases HR and contractility. Treats hypertension and CAD.

Front 30

Carvedilol

Back 30

alpha1/beta blocker
Decreases peripheral resistance
Decreases HR and contractility
Treats heart failure

Carvill - old white dude - heart failure

Front 31

Epinephrine

Back 31

Alpha agonist at high doses
Beta agonist at all doses

Vasoconstriction - a1
HR and contractility - b1
Increases cardiac output and BP to treat cardiac arrest and severe hypotension, anaphylaxis

Front 32

ephedrine

Back 32

stimulates both alpha and beta. Beta more. Increases systolic and diastolic blood pressure.

Front 33

dopamine

Back 33

agonist at alpha, beta, and D receptors. Emergency treatment of severe hypotension and shock.

Front 34

amphetamine

Back 34

stimulates the release of NE, E and DA. Leads to arousal state.

Front 35

Cocaine

Back 35

Blocks the Na/K ATPAse that reuptakes NE, 5HT, and DA
Can cause HTN, MI, arrhythmia

Front 36

Reserpine

Back 36

inhibits the neuron's ability to store NE DA and 5HT, leading to depletion. Has been used to treat hypertension but can cause serious depression. Anti-cocaine basically.

Front 37

Tyramine

Back 37

releases 5ht,DA,NE
Essentially acts like cocaine
Tyra banks coked out

Front 38

methyldopa

Back 38

alpha2 agonist that reduces the release of NE and other NTs. Treats hypertension.

Front 39

Guanethidine

Back 39

Displaces NE from vesicles, inhibiting it's release.