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39 Cards in this Set

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Pilocarbine
muscarinic agonist
Used topically on the eye to contract the iris. Opens canal of schlemm, increases outflow of aqueous. For glaucoma
Bethanecol
muscarinic agonist
increased ladder contraction and increased sphincter relaxation - helps you pee!
Parasympathetic side effects - bradycardia, hypotension, sweating, salivation, diarrhea.
Carbachol
muscarinic agonist
Topical eye drop for glaucoma. Contracts pupil, canal of schlemm opens. Aqueous humor leaves.
Atropine
Competetive muscarinic antagonist. Causes sedation and at high doses, psychosis. Can cause tachycardia and vasodilation. Sympathetic effects.
Used as an antidote for ACh inhibitor poisoning, emergency bradycardia
Scopolamine
competitive muscarinic antagonist. Derived from atropine. Sympathetic effects.
Prevents motion sickness.
Scopalamine - prevents you from scooping up vomit.
Ipratropium
blocks the muscarinic cholinergic receptors in the smooth muscles of the bronchi in the lungs. This opens the bronchi, and provides relief in chronic obstructive pulmonary disease and acute asthma. This is inhaled.
Physostigmine
anticholinesterase - can cross BBB. counteracts atropine. Can treat claugoma in eyedrop form.
Neostigmine
anticholinesterase
Treats myasthenia gravis, used to stimulate GI tract and bladder, and overcome non-depolarizing nm blockade. Does not cross BBB.
pyridostigmine
Anti-AChE - treats myasthenia gravis
tubocurarine
competetive inhibitor at NMJ
succinylcholine
depolarizing agent at NMJ
pancuronium
competetive inhibitor at NMJ

remember - cur - curare - nmj blocker
Vecuronium
competitive inhibitor at NMJ
Norepinephrine
alpha adrenergic agonist
Used as a pressor in emergency situations, shock.
Side effects - angina, MI, arrhythmias
Phenylephrine
Alpha1 agonist.
Treats severe hypotension and shock, nasal congestion, and pupil dilation.
Methoxamine
Alpha 1 agonist
Increases peripheral resistance
Reflex bradycardia
metaraminol
Alpha 1 agonist
Prevents hypotension in anesthesia situation
tetrahydrozoline
Alpha agonist - visine! Contracts blood vessels - gets the red out.
clonidine
Alpha 2 agonist - decreases norepinephrine release. Treatment for hypertension
Phentolamine
Short acting, reversible alpha antagonist Diagnoses pheochromocytoma.
PHEntolamine - PHEochromocytoma
Phenoxybenzamine
Irreversible alpha receptor antagonist.
Treatment of pheochromocytoma (too much adrenergic activity)
Phenoxy - pheochromo
Prazosin
Alpha 1 antgonist. Decreases blood pressure. Decreases prostatic and bladder neck contraction - helps you pee in BPH.
Praz-prostate.
Isoproterenol
Potent Beta agonist. Increases heart rate and contractility.
SE- tachyarrhythmias, anxiety, puonary edema
Dobutamine
B1>>B1 Agonist
Heart failure and cardiogenic shock. INcreases HR and contractility
Albuterol
INhaled B2 agonist - bronchodilator
terbutaline
B2 agonist - stops premature labor by relaxing the uterus, and bronchodilator for asthma.
Terbutaline - prevents turbulent flow of air thru lungs, turbulent delivery
metaproterenol
B2 agonist - asthma treatment
Propanolol, nadolol, timolol
Beta antagonist. HTN Tx.
Can cause bronchoconstriction
metoprolol
Beta1 antagonist - decreases HR and contractility. Treats hypertension and CAD.
Carvedilol
alpha1/beta blocker
Decreases peripheral resistance
Decreases HR and contractility
Treats heart failure

Carvill - old white dude - heart failure
Epinephrine
Alpha agonist at high doses
Beta agonist at all doses

Vasoconstriction - a1
HR and contractility - b1
Increases cardiac output and BP to treat cardiac arrest and severe hypotension, anaphylaxis
ephedrine
stimulates both alpha and beta. Beta more. Increases systolic and diastolic blood pressure.
dopamine
agonist at alpha, beta, and D receptors. Emergency treatment of severe hypotension and shock.
amphetamine
stimulates the release of NE, E and DA. Leads to arousal state.
Cocaine
Blocks the Na/K ATPAse that reuptakes NE, 5HT, and DA
Can cause HTN, MI, arrhythmia
Reserpine
inhibits the neuron's ability to store NE DA and 5HT, leading to depletion. Has been used to treat hypertension but can cause serious depression. Anti-cocaine basically.
Tyramine
releases 5ht,DA,NE
Essentially acts like cocaine
Tyra banks coked out
methyldopa
alpha2 agonist that reduces the release of NE and other NTs. Treats hypertension.
Guanethidine
Displaces NE from vesicles, inhibiting it's release.