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65 Cards in this Set
- Front
- Back
- 3rd side (hint)
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Acetylcholine
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Rapid Hydrolysis
Parasympathomimetic (increase ACh--> stimulating muscarinic receptors) |
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Bethanechol
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Choline Ester w/ CH3 and NH2 - resists degradation
more muscarinic than nicotinic effect Parasympathomimetic (increase ACh--> stimulating muscarinic receptors) |
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Pilocarpine
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Alkaloid
Parasympathomimetic (increase ACh--> stimulating muscarinic receptors) 3X (tertiary compound) |
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Neostigmine
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Reversible AChE Inh
Parasympathomimetic (leads to increase ACh--> stimulating muscarinic receptors) |
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Parathion/Malathion
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Organophosphate Irreversible AChE Inh
Parasympathomimetic (leads to increase ACh--> stimulating muscarinic receptors) DOA: 100s of hours |
Tx of acute intoxication:
Atropine (large doses) plus Pralidoxime (reactivates AChE) |
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Atropine
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Anticholinergic (Antimuscarinic)
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Tropicamide
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Anticholinergic (Antimuscarinic)
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Ipratropium
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asthma, blocks M3 (Nitric Oxide)
Anticholinergic (Antimuscarinic) |
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Chlorpromazine
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antipsychotic
Anticholinergic (Antimuscarinic) |
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Diphenhydramine
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Benadryl, anti H1
Anticholinergic (Antimuscarinic) |
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Fluoxetine
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antidepressant
Anticholinergic (Antimuscarinic) |
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Trimethaphan, Mecamylamine
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Antinicotinic - Ganglionic Blocking Agents
Tri- charged, does not cross BBB Meca - 2X - produces CNS effects |
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D-tubocurarine
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competitive, reversible, long
Neuromuscular blocking |
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Succinylcholine
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depolarizing, short
Neuromuscular blocking |
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Amphetamine
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releases NE at terminal
Sympathomimetic |
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Pseudoephedrine
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decongestant
Sympathomimetic |
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Epinephrine
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a1,a2,b1,b2
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Dopamine
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DA1,DA2,a1,B1
DA agonist |
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Fenoldapam
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DA1 agonist
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tx hypertensive crisis
relaxes renal arteries improves renal function |
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Phenylephrine
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a1
Alpha Agonists Sympathomimetics (Adrenergic Agonist) |
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Clonidine
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a2
Alpha Agonists |
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Phentolamine
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anti a1,a2
competitive reversible Alpha antagonist |
tx hypertensive crisis
relax vascular smooth muscle |
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Phenoxybenzamine
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anti a1, a2
competitive irreversible Alpha antagonist |
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Prazosin
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Anti a1
Alpha antagonist |
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Tamsulosin
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Anti a1
Alpha antagonist |
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Isoproterenol
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B1, B2
Beta agonist |
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Dobutamine
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B1
beta agonists |
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Albuterol
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B2
Beta Agonists |
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Salmeterol
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B2
Beta Agonists |
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Ritodrine
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B2
Beta Agonists |
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Propranolol
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anti B1,B2
B-Antagonists (competitive, reversible) |
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Timolol
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anti B1, B2
B-Antagonists (competitive, reversible) |
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Metoprolol
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anti B1
B-Antagonists (competitive, reversible) |
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Bisoprolol
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anti B1
B-Antagonists (competitive, reversible) |
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Betaxolol
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anti B1
B-Antagonists (competitive, reversible) |
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Labetalol
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nonselective anti B1,B2,a1
B-Antagonists (competitive, reversible) to tx hypertensive crisis & hypertensive encephalopathy Lowers BP and slows HR by blocking both a1 and b1 adrenergic receptors |
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Carvedilol
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anti B1,B2,a1
B-Antagonists (competitive, reversible) |
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Fluticasone
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ICS
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Antitoxin
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Botulinum-prevents ACh release at presynaptic terminal
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Cathartics
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(Castor oil)- laxative
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Sodium bicarbonate
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acid neutralizer
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Fluid/electrolyte replacement
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Misc tx
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Cardiovascular support
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Misc tx
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Histamine
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Allergies (H1=acute allergic rxns/H2=gastric acid secretion)
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Cromolyn Sodium
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Mast cell stabilizer - slow
Allergies (H1=acute allergic rxns/H2=gastric acid secretion) |
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Diphenhydramine
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anti H1-1st generation - rapid
Allergies (H1=acute allergic rxns/H2=gastric acid secretion) |
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Fexofenadine
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anti H1-2nd generation - rapid
Allergies (H1=acute allergic rxns/H2=gastric acid secretion) |
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Loratadine
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anti H1-2nd generation - rapid
Allergies (H1=acute allergic rxns/H2=gastric acid secretion) |
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Montelukast
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leukotriene Receptor inhibitor - fast
Allergies (H1=acute allergic rxns/H2=gastric acid secretion) |
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Fluticasone
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ICS - slow
Allergies (H1=acute allergic rxns/H2=gastric acid secretion) |
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Epinephrine
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a1,a2,B1,B2
Allergies (H1=acute allergic rxns/H2=gastric acid secretion) |
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SABA
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Albuterol (1-5min onset, 2-6hr duration)
B2 Adrenergic Receptor Agonists |
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LABA
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Salmeterol (15-30min onset, 12hr duration)
Formoterol B2 Adrenergic Receptor Agonists |
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Theophylline
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Phosphodiesterase Inhibitor
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Ipratropium
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block M3 - can't tolerate B agonist
Antimuscarinic |
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Beclomethasone
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7-14 days
inhaled corticosteroids (anti-inflammatory) |
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Fluticasone
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inhaled corticosteroids (anti-inflammatory)
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Prednisone
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oral corticosteroids (anti-inflammatory)
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Prednisolone
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oral corticosteroids (anti-inflammatory)
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Cromolyn
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inhibitor of mast cell degranulation
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Nedocromil
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inhibitor of mast cell degranulation
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Zileuton
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synthesis inhibitor
Leukotriene pathway inhibitors |
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Zafirlukast
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LTRAs
Leukotriene pathway inhibitors |
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Montelukast
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LTRAs
Leukotriene pathway inhibitors |
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Omalizumab
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Anti-IgE
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