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22 Cards in this Set
- Front
- Back
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Where is epinephrine not produced?
a) adrenal medulla b) hypothalamus c) spinal cord d) brainstem |
c) spinal cord
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T/F
Epinephrine's "L" isomer is more potent than its "D" isomer. |
true
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T/F
Epinephrine is active orally. |
false
(inactive orally) |
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Epinephrine's cardiac actions include all of the following except:
a) increase cardiac contractility through PKA-dependent phosphorylation of L-type channels to increase Ca++ entry. b) increase in rate of relaxation through PKA-dependent phosphorylation of Ca++ ATPase c) increase heart rate by increasing the rate of depolarization of the SA node d) all of the above are effects e) none of the above are effects |
d) all of the above are effects
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Vascular effects of epinephrine may include
a) contraction b) relaxation c) a & b d) none of the above |
c) a & b
depending on receptor |
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metabolic effects of Epinephrine include
a) increase in lipolysis b) increase in insulin release c) increase in metabolic rate d) increase in glycongenolysis e) a, b, c f) a, c, d g) all of the above |
f) a, c, d
(it decreased insulin release) |
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The respiratory effects of epinephrine include
a) relaxing bronchi b) constricting bronchi c) stabilizing mast cells d) secreting mast cells e) a & c f) b & c g) b & d |
e) a & c
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The smooth muscle effects of EPI include
a) sphincters constricted b) peristalsis increased c) uterine smooth muscle contracted d) all of the above e) none of the above |
a) sphincters constricted
(peristalsis decreases, uterine smooth muscle is relaxed - although when pregnant it can be contracted by alpha-1) |
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Epinephrine has all of the effects except
a) cardiac b) vascular c) skeletal muscle d) metabolic e) respiratory f) smooth muscle g) ocular |
c) skeletal muscle
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Some of the ocular effects EPI has include
a) decrease in intraocular pressure by enhancing outflow b) decrease in intraocular pressure by decreasing outflow c) mydriasis d) miosis e) a & c f) a & d g) b & c |
e) a & c
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All of the following are therapeutic uses of EPI except
a) anaphylactic shock b) mydriasis c) prolong local anesthetics d) cardiac stimulant e) bronchial asthma f) glaucoma |
b) mydriasis
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Side effects of EPI include all of the following except
a) tachycardia b) tremors c) arrhythmias d) increased capillary filtration |
d) increased capillary filtration
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T/F
Epinephrine is contraindicated in hypothyroidism. |
false
(HYPERthyroidism) |
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Which of the following will cause a drug interaction with EPI?
a) tricyclic antidepressent b) cocaine c) MAO inhibitor d) all of the above e) none of the above |
d) all of the above
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T/F
The "D" isomer for NE is more potent than the "L" isomer. |
false
(its the opposite) |
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T/F
Epinephrine activates alpha-1, alpha-1, beta-1, beta-2, and beta-3 receptors. |
false
(not beta-3) |
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T/F
NE will activate alpha-1, alpha-1, beta-1, and beta-3 receptors, but is limited to beta-2. |
true
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T/F
NE is inactive orally. |
true
(IV only) |
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Some of the cardiac effects of NE include:
a) vasodilation b) vasoconstriction c) increased cardiac output d) decreased heart rate e) a & c f) b & c g) b, c, & d |
g) b, c, & d
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What is a therapeutic use of NE?
a) increases BP b) decrease BP/antihypertensive c) relax bronchial smooth muscle d) nasal decongestant |
a) increases BP
(limited conditions) |
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What are some side effects of NE?
a) excessive vasodilation b) excessive vasoconstriction c) increased capillary filtration d) decreased capillary filtration e) a & c f) b & d g) b & c |
g) b & c
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NE is contraindicated in what?
a) hyperthyroidism b) CVA c) hypothyroidism d) aneurysm e) a & b f) b & d g) a, b, & d h) all of the above |
f) b & d
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