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24 Cards in this Set

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ADVERSE DRUG EVENT (ADE)
An injury caused by a medication or failure to administer an intended medication; may or may not be preventable( due to errors); may or may not cause client harm; includes all adverse drug reactions but is not caused by a medication error; also includes expected or anticipated side effects of medications
ADVERSE DRUG REACTION (ADR)
Any unexpected, unintended, undesired, or excessive response to a medication; may or may not be preventable, may or may not harm client; all ADR’s are ADE’s but not all ADE’s are ADR’s.
AGONIST
A drug that binds to and stimulates the activity of one or more biochemical receptor types in the body, resulting in stimulatory or agonistic drug effects.
ANTAGONIST
A drug that binds to and inhibits the activity of one or more biochemical receptor types in the body; resulting in inhibitory or antagonistic drug effects. Antagonists are also called inhibitors.
CHEMICAL NAME
The name that describes a drug’s chemical composition and molecular structure.
CONTRAINDICATION
Any condition, including any current or recent drug therapy, especially related to disease states or other client characteristics that renders a particular form of treatment improper or undesirable.
DRUG EFFECT
The physiological reaction of the body to a drug. It is similar to a drug’s therapeutic effect on that it constitutes how the function is affected as a whole by the drug. The terms onset, peak and duration are used to describe drug effects.
DRUG INTERACTION
Alteration of the pharmacological activity of a given drug by the presence of one or more additional drugs, usually due to effects on the activity of enzymes required for metabolism of all involved drugs.
FIRST-PASS EFFECT
The initial metabolism in the liver of a drug absorbed from gastrointestinal (GI) tract, before the drug reaches systematic circulation through the blood stream.
GENERIC NAME
Name given to a drug approved by Health Canada. The name is not protected by trademark
ONSET OF ACTION
The time it takes for the drug to elicit a therapeutic response
PEAK EFFECT
The time it takes for a drug to reach its maximum therapeutic response in the body
PHARMACOTHERAPEUTICS
Treatment of pathological conditions through the use of drugs
RECEPTOR
Molecular structure within or on the outer surfac eof cells
SIDE EFFECT
An undesireable effect of a medication that is expected or anticipated to occur in a predictable percentage of clients who receive a medication
STEADY STATE
Physiological state in which the amount of drug removed via elimination is equal to the amount of drug absorbed with each dose
THERAPEUTIC EFFECT
The desired or intended effect of a particular medication
TRADE NAME
Final name given to a drug
PHARMACOKINETICS
The study of drug distributionrates among various body compartments after a drug has entered the body. Include the phases of absorpton, distribution, metabolism, excretion of drugs (What the drug does to the body)
PHARMACODYNAMICS
The study of biochemical & physiological interactions of drugs (What the body does to the drug)
DRUG CLEARANCE
Elimination of drug by hepatic & renal system
HALF-LIFE
Time required to reduce plasma concentration of drug to half the original concentration
DRUG PLASMA CONCENTRATION
Amt. of free drug in blood plasma
ADJUNCT THERAPY
Combination drug therapy used when clients condition does not respond adequetly to a single drug