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11 Cards in this Set
- Front
- Back
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what are cholinegic-blocking drugs
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Cholinergic-blocking agents block the action of the neurotransmitter ACh at the muscarinic receptors in the PSNS
Anticholinergics Blocking the PSNS allows the parasympathetic nervous system to dominate Competitive antagonist |
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what are the major sites of anticholinegic drugs
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heart, respiratory tract, GI tract, Urinary bladder, eye, and exocrine glands.
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what effects to anticholinergic drugs have
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Anticholinergic have effects opposite of the cholinergics
Pupils dilate (mydriasis) and relax eye GI tract – decrease in GI motility, GI secretions, and salivation. Heart – increased heart rate In the respiratory tract, decreased secretions from nose, mouth, pharynx, and bronchi. |
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what is the toxicity of anticholinergic drugs
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Vary narrow difference between therapeutic and toxic
Symptomatic and supportative treatment Lavage the stomach, charcoal, laxative |
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what are some anticholinergic drugs
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Atropine
Bentyl Robinol Transderm-Scop Detrol |
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what is the anticholinergic drug-atropine
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Used preoperatively to decrease salivation
Give as second drug in asystole – 1 mg. Give if symptomatic with drop in heart rate Atropine type overdoses – use physostigmine to reverse |
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what is the anticholinergic drug-bentyl
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Antispasmodic
Use with phenobarbital for colic in infants 15 mg IM babies PO |
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what is the drug anticholinergic-robinul
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Used as adjunct treatment in peptic ulcer disease
Can use as a preop to reduce salivation Inhibits the motility of the GI tract and genitourinary tract and decreases volume of gastric and pancreatic secretions |
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what is the drug anticholinergic drug- transdrem scop
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Prevention of motion sickness
Apply a patch behind the ear 5-6 hours before travel Use the synthetic derivative now because of fewer side effects |
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what is the anticholinergic drug-detrol
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Used for urinary frequency, urgency, and urge incontinence caused by bladder (detrusor) overactivity
Less incidence of dry mouth with Detrol Also Ditropan – very commonly prescribed as an antispasmotic for bladder problems |
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what are teaching tips for anticholinergic drugs
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Dry mouth is common, can chew gum, or suck hard candy, should regularly brush teeth
Blurred vision – careful driving Sensitive to light At risk for heat stroke because agents effect the heat-regulating mechanisms of the body |
