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4 Cards in this Set
- Front
- Back
- 3rd side (hint)
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Affinity |
The property of a drug to bind to a binding site on the receptor |
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Efficacy |
A measure of the ability of the drug to produce a measurable response |
This can be zero positive or negative value drugs that |
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Drugs that bind to receptors resemble the ____ And have |
Drugs that bind to receptors often resemble the natural or endogenous ligand structurally and have specific affinity for specific receptors |
Salbutamol and adrenaline |
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1. receptors generally have a high degree of ___ 2. receptors bind only molecules _____ 3. receptors do not bind ____ 4. binding to multiple receptors accounts for ___ |
1. receptors generally have a high degree of drug (ligand) specificity 2. receptors bind only molecules with a unique three dimensional topography and chemistry 3. receptors do not bind closely related molecules 4. binding to multiple receptors accounts for the appearance of unwanted side effects |
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