Pharmacology Basis Of Therapeutics Quiz 1

Front 1

True/False
Post Ganglionic autonomic nerves are mylenated.

Back 1

False. Pre Ganglionic

Front 2

True/False
Stimulation of autonomic nerves always results in excitation/activation.

Back 2

False. somatic nerves

Front 3

Preganglioninc sympathetic nerves release which neurotransmitter? ______________

Back 3

Acetylcholine

Front 4

Release of ______________ (neurotransmitter) acting on ____________ (receptors) on the ____________ muscle causes Mydriasis.

Back 4

Norepinephrine
alpha 1
radial

Front 5

The baro reflex will decrease heart rate by causing release of ____________ on the SA node to act on ____________ receptors.

Back 5

Acetylcholine
m2 (muscarinic 2)

Front 6

Atropine would increase/decrease tear production, increase/decrease salivation and increase/decrease secretions in the lung.

Back 6

decrease
decrease
decrease

Front 7

True/False
Pre Ganglionic autonomic nerves are mylenated.

Back 7

True

Front 8

True/False
Stimulation of somatic nerves always results in excitation/activation.

Back 8

True

Front 9

Postganglioninc sympathetic nerves release which neurotransmitter?
_____________

Back 9

Norepinephrine

Front 10

Release of ______________ (neurotransmitter) acting on _____________ (receptors) on the _____________ muscle causes Miosis.

Back 10

Acetylcholine
m3 (muscarinic 3)
circular

Front 11

The baro reflex will increase blood pressure by causing release of _____________ to act on alpha 1 receptors.

Back 11

Norepinephrine

Front 12

Acetylcholine would increase/decrease tear production, increase/decrease salivation and increase/decrease secretions in the lung.

Back 12

increase
increase
increase

Front 13

True/False
Somatic nerves are mylenated.

Back 13

True

Front 14

True/False
Stimulation of autonomic nerves may result in relaxation/inactivation.

Back 14

True

Front 15

Preganglioninc parasympathetic nerves release which neurotransmitter? ______________

Back 15

Acetylcholine

Front 16

Release of _____________ (neurotransmitter) acting on _____________ (receptors) on the __________ muscle results in accommodation.

Back 16

acetylcholine
m3 (muscarinic 3)
ciliary

Front 17

The baro reflex will increase heart rate by causing release of ____________ on the SA node to act on ___________ receptors.

Back 17

norepinephrine
beta 1

Front 18

True/False
Postganglionic sympathetic nerves are mylenated.

Back 18

False. are unmylenated.

Front 19

Release of _____________ (neurotransmitter) acting on ____________ (receptors) in the ____________ (area of heart) will result in a decreased heart rate.

Back 19

Acetylcholine
m2 (muscarininc 2)
SA node

Front 20

Urination is caused by ___________ (transmitter) acting on _________ (receptors) on the ___________ (muscle) causing contraction while at the same time causing the ____________ (muscle) to relax.

Back 20

ACH
M3
Detruser
sphincter

Front 21

True/False
M2 receptors on Norpeinephrine neurons are autoreceptors.

Back 21

False. on Acetylcholine

Front 22

Epinephrine would increase /decrease pupil diameter.

Back 22

increase

Front 23

Ejaculation is caused by ___________ (transmitter) acting on _________ (receptors) while an erection is caused by _____________ (transmitter) acting on ____________ (receptors

Back 23

NE
alpha 1
ACH
M3

Front 24

True/False
M2 receptors on Acetylcholine neurons are autoreceptors:

Back 24

True

Front 25

Pilomotor muscle contraction is caused by _________ (transmitter) acting on _________ (receptors) while generalized sweating is caused by ___________ (transmitter) acting on ___________ (receptors)

Back 25

NE
alpha 1
ACH
M3

Front 26

True/False Alpha 2 receptors on Acetylcholine neurons are autoreceptors.

Back 26

False. on Norepinephrine neurons

Front 27

True/False
Somatic nerves have ganglia that are found close to the organs they innervate.

Back 27

False. Parasympathetic

Front 28

True/False
Autonomic nerves have unmylinated postganglionic neurons.

Back 28

True

Front 29

True/False
Somatic nerves always cause excitation

Back 29

True

Front 30

Parasympathetic nerves have long/short preganglionic neurons and produce a localized/generalized response to stimuli.

Back 30

long
localized

Front 31

Acetylcholine acting on __________ receptors in the _______ muscle cause accommodation.

Back 31

M3
Cilliary

Front 32

Activation of ___________ receptors in the heart by ______ causes a decrease in heart rate.

Back 32

M2
Acetylcholine

Front 33

_________receptors increase renin release and ________receptors decrease insulin release.

Back 33

B1
alpha 2

Front 34

True/False
Parasympathetic nerves have ganglia that are found close to the organs they innervate.

Back 34

True

Front 35

Somatic nerves control the external/internal environment

Back 35

external

Front 36

True/False
Autonomic nerves may cause excitation and/or inhibition of tissues they innervate

Back 36

True

Front 37

Sympathetic nerves exit the spinal cord from the _________ region and usually release ____________ as the transmitter.

Back 37

Thoracic-lumbar
Norepinephrine

Front 38

Norepinephrine acting on __________ receptors in the radial muscle cause __________.

Back 38

alpha 1
mydriasis

Front 39

Activation of ___________ receptors in the heart by Norepinephrine causes increased ___________ and __________in the atria.

Back 39

B1
conduction
contractility

Front 40

_______ receptors constrict the Detruser muscle and _______ the sphincter muscle due to Acetylcholine in the urinary bladder.

Back 40

M3
relax

Front 41

True/False
Acetylcholine is the preganglionic transmitter released from sympathetic nerves

Back 41

True

Front 42

Somatic nerves activate _________ receptors in skeletal muscle

Back 42

Nicotinic

Front 43

Parasympathetic nerves exit the spinal cord from the ______ region and always release ______ from postganglionic nerves

Back 43

Cranial sacral
Acetylcholine

Front 44

True/False
Somatic nerves are mylenated

Back 44

True

Front 45

Norepinephrine acting on _____ receptors causes contraction of the spleen and Contraction/relaxation of veins

Back 45

alpha 1
contraction

Front 46

Acetylcholine would Increase/decrease GI secretions, Increase/decrease tear production and Increase/decrease urination

Back 46

Increase
Increase
Increase

Front 47

Which of the following is/are characteristics of sympathetic nerves?
1) Cranial-sacral outflow from spinal cord
2) Generalized area of stimulation
3) Long preganglionic fibers
4) No paralysis after denervation
A = 1,2 3, are correct
B = 1,3 are correct
C = 2 and 4 are correct
D = 4 only
E = All of the choices are correct
F = None of the choices are correct

Back 47

C = 2 and 4 are correct

Front 48

Sympathetic tone predominates in which of the following systems at rest?
a) Sino-atrial node
b) Radial muscle of eye
c) Bronchial smooth muscle
d) Liver
e) All of the choices are correct
f) None of the choices are correct

Back 48

b) Radial muscle of eye

Front 49

Which of the following is/are correct?
a) Autonomic nerve activation requires conscious input
b) The spinal cord carries mainly motor information from the CNS to the periphery
c) The brainstem integrates basal functions necessary to maintain life
d) Purinergic nerves release ACH in the GI tract.
e) All of the choices are correct
f) None of the choices are correct

Back 49

c) The brainstem integrates basal functions necessary to maintain life

Front 50

Which of the following is/are true about the baroreflex?
a) It is responsible for long term control of blood pressure
b) It only responds to increases in blood pressure
c) Is completely blocked by Prazosin
d) Is completely blocked by atropine
e) All of the choices are correct
f) None of the choices are correct

Back 50

f) None of the choices are correct

Front 51

Which of the following combinations is/are correct?
a) Alpha 1 activation - contracts GI sphincters
b) M3 receptor activation – accommodation
c) M2 receptor activation – Bradycardia
d) Beta 1 receptor activation – renin release
e) All of the choices are correct
f) None of the choices are correct

Back 51

e) All of the choices are correct

Front 52

Somatic nerves:
a) Form ganglia near the tissues they innervate
b) Control mainly external environment
c) Are unmylenated
d) Cause both contraction and relaxation
e) All are correct choices
f) None of the above are correct choices

Back 52

b) Control mainly external environment

Front 53

Which of the following is/are true?
a) Presynaptic receptors are always autoreceptors
b) The autoreceptors on cholinergic terminals are the M3 subtype
c) Beta two receptors on norpeinephrine containing nerve terminals are autoreceptors
d) The order of potency for alpha two autoreceptors is alpha 2a > alpha 2c.
e) All of the above are correct
f) None of the above are correct

Back 53

d) The order of potency for alpha two autoreceptors is alpha 2a > alpha 2c.

Front 54

Which of the following is/are true?
a) Alpha 1 receptor activation contracts circular muscle in the eye
b) M1 receptor activation causes accommodation
c) Beta 2 receptor activation decreases mucous secretion in bronchial smooth muscle
d) Alpha 2 receptor activation decreases renin secretion
e) All of the above are correct
f) None of the above are correct

Back 54

f) None of the above are correct

Front 55

At rest sympathetic tone predominates in which of the following tissues?
a) Sino-atrial node
b) Radial muscle
c) Bronchioles
d) Bladder
e) A and C are correct
f) B and D are correct

Back 55

b) Radial muscle

Front 56

Which of the following is/are correct?
a) Autonomic nerves control essential bodily functions without conscious input.
b) The spinal cord carries mainly sensory information to the CNS.
c) The hypothalamus is the integrative center for the autonomic nervous system.
d) The brain responds mainly to the external environment.
e) A and C are correct
f) All of the above are correct

Back 56

e) A and C are correct

Front 57

Somatic nerves
a) All use Acetylcholine as the neurotransmitter
b) Always cause excitation
c) Are all mylenated
d) Contain spinal and brainstem reflex arch’s
e) All of the above are correct
f) None of the above are correct

Back 57

e) All of the above are correct

Front 58

Sympathetic nerves
a) Are all mylenated
b) Respond to the external environment
c) Are uninterrupted from the CNS to the target tissue
d) All have ganglia located within the spinal cord
e) All of the above are correct
f) None of the above are correct

Back 58

f) None of the above are correct

Front 59

Which of the following is/are correct?
a) Parasympathetic nerves originate in the cranial-sacral portion of the spinal cord.
b) Sympathetic nerves have long preganglionic neurons.
c) Parasympathetic nerves produce a localized tissue response
d) Sympathetic nerves always use Norepinephrine as the neurotransmitter
e) A and C are correct
f) All of the above are correct

Back 59

e) A and C are correct

Front 60

During exercise the sympathetic nervous system predominates in the following tissues:
1) SA node
2) Radial muscle of eye
3) Veins
4) Coronary arteries
A = 1,2,3 are correct
B = 1 and 3 are correct
C = 2 and 4 are correct
D = 4 only is correct
E = All are correct
F = None are correct

Back 60

A = 1,2,3 are correct

???
E?

Front 61

Parasympathetic activation would:
1) Cause Mydriasis
2) Increase viscous saliva
3) Increase localized sweating
4) Increase bronchial secretions
A = 1,2 3 are correct
B = 1 and 3 are correct
C = 2 and 4 are correct
D = 4 only is correct
E = All are correct
F = None are correct

Back 61

D = 4 only is correct

Front 62

Which of the following is/are correct?
a) Sympathetic nerves release Norepinephrine from varicosities all along the axon
b) Sympathetic nerves all exit from the central portion of the spinal cord
c) Norepinephrine release from vesicles is an all or none process.
d) Dopamine – Beta- Hydroxylase is released from vesicles with Norepinephrine
e) All of the above are correct
f) None of the above are correct

Back 62

e) All of the above are correct

Front 63

Sympathetic activation would cause which of the following?
1) Mydriasis
2) Erection in males
3) Tachycardia
4) Accomodation
A = 1,2 3 are correct
B = 1 and 3 are correct
C = 2 and 4 are correct
D = 4 only is correct
E = All are correct
F = None are correct

Back 63

B = 1 and 3 are correct

Front 64

Which of the following is/are not characteristics of sympathetic nerves?
1) Cranial-sacral outflow from spinal cord
2) Generalized area of stimulation
3) Responses blocked by Atropine
4) Short pre-ganglionic fibers
A = 1, 2,and 3 are correct
B = 1 and 3 are correct
C = 2 and 4 are correct
D = 4 only is correct
E = All are correct
F = None are correct

Back 64

B = 1 and 3 are correct

Front 65

The parasympathetic nervous system predominates in which of the following tissues?
1) Uterus
2) Ciliary muscle of eye
3) Ventricular muscle
4) Salivary glands

A = 1, 2,and 3 are correct
B = 1 and 3 are correct
C = 2 and 4 are correct
D = 4 only is correct
E = All are correct
F = None are correct

Back 65

C = 2 and 4 are correct

Front 66

Which of the following would be experienced by someone receiving a cholinergic agonist?
A) Increased heart rate
B) Bronchoconstriction
C) Contraction of GI sphincters
D) Mydriasis
E) All of the above are correct
F) None of the above are correct

Back 66

B) Bronchoconstriction

Front 67

Which of the following would cause miosis?
1) Alpha 1 agonist
2) Alpha 1 antagonist
3) M 3 antagonist
4) M 3 agonist
A = 1, 2,and 3 are correct
B = 1 and 3 are correct
C = 2 and 4 are correct
D = 4 only is correct
E = All are correct
F = None are correct

Back 67

C = 2 and 4 are correct

Front 68

Parasympathetic nerves
1) Always have ganglia
2) Have short pre-ganglionic fibers
3) Have localized areas of innervation
4) Post ganglionic fibers are mylenated
A = 1, 2,and 3 are correct
B = 1 and 3 are correct
C = 2 and 4 are correct
D = 4 only is correct
E = All are correct
F = None are correct

Back 68

B = 1 and 3 are correct

Front 69

Which of the following is/are true?
A) Somatic nerves sometimes have ganglia
B) Spinal reflexes are present in both somatic and autonomic systems
C) Post-ganglionic automic nerves are mylenated
D) Somatic nerves have plexus
E) All of the above are correct
F) None of the above are correct

Back 69

B) Spinal reflexes are present in both somatic and autonomic systems

Front 70

Sympathetic nervous system at maximal activation can produce all of the following except:
A) Mydriasis
B) Increased renal blood flow
C) Reduced intestinal motility
D) Bronchial relaxation
E) Tachycardia
F) None of the above

Back 70

B) Increased renal blood flow

Front 71

Which of the following is/are true?
A) Central centers in hypothalamus and brainstem regulate levels autonomic nerve activity
B) Somatic nerves originate in relay centers in the thalamus
C) Purinergic nerves in GI tract use acetylcholine as the neurotransmitter
D) Autonomic nerves innervate only smooth muscle and glands
E) All of the above are correct
F) None of the above are correct

Back 71

A) Central centers in hypothalamus and brainstem regulate levels autonomic nerve activity

Front 72

Which of the following is /are correct?
A) Ganglia for somatic nerves are in the CNS.
B) Autonomic nerves always cause excitation
C) Loss of somatic nerves results in paralysis
D) Autonomic nerves respond mainly to the external environment
E) All of the above are correct
F) None of the above are correct

Back 72

C) Loss of somatic nerves results in paralysis

Front 73

Which of the following are mediated by alpha 1 receptors?
A) Lipolysis
B) Increased cardiac contractility
C) Erections in males
D) Miosis
E) All of the above are correct
F) None of the above are correct

Back 73

F) None of the above are correct

A???

Front 74

Sympathetic tone predominates during exercise in the following tissues ?
a. Liver
b. Radial muscle
c. Kidney - renin secretion
d. Sino-atrial node
e. All of the above
f. None of the above.

Back 74

e. All of the above

Front 75

Somatic Nervous System:
@Has ganglia
@Has short Preganglionic nerve fibers
@Always causes excitation
@Nerve fibers lack mylenation
@All of the above
@None of the above

Back 75

@Always causes excitation

Front 76

Alpha-1-Agonists would cause:
@Miosis
@Copious salivation
@Decreased renin release
@Increased Insulin release
@All of the above
@None of the above

Back 76

@Decreased renin release

Front 77

Selective Beta 2 agonists:
@Dilate veins
@Relax urinary bladder
@Increase Insulin secretion
@Dilate bronchial smooth muscle
@All of the above
@None of the above

Back 77

@All of the above

Front 78

Which of the following is/are correct for presynaptic receptors ?
@Alpha2 - increases Norepinephrine release
@M2 - decreases Acetylcholine release
@Adenosine - Increase Norepinephrine release
@D2 - Inhibit Norepinephrine release
@A and B are correct
@B and D are correct

Back 78

@B and D are correct

Front 79

Which of the following is/are true?
a. The brainstem is the integrative center for autonomic nerve function
b. The hypothalamus is the integrative center for life sustaining basal functions
c. Afferent sensory information only concerns itself with your relative position in space
d. Efferent motor information controls the body’s response to the environment
e. All of the choices are correct
f. None of the choices are correct

Back 79

d. Efferent motor information controls the body’s response to the environment

Front 80

Which of the following is/are true about motor systems?
a. Purinergic nerves release acetylcholine
b. Somatic nerves mainly control movement
c. Autonomic nerves only control smooth muscle
d. Somatic nerves control skeletal and cardiac muscle
e. All of the choices are correct
f. None of the choices are correct

Back 80

b. Somatic nerves mainly control movement

Front 81

Which of the following is/are true?
a. Sympathetic nerves produce a generalized response to nerve stimuli
b. Autonomic nerves all release acetylcholine from preganglionic nerve terminals
c. Somatic nerves always cause excitation
d. Autonomic nerves control the internal environment
e. All of the choices are correct
f. None of the choices are correct

Back 81

e. All of the choices are correct

Front 82

In the autonomic nervous system
1) Sympathetic nerves form plexus
2) Ganglia in parasympathetic nerves are in or close to the tissue they innervate
3) Parasympathetic nerves leave the spinal cord in the cranio-sacral region
4) The adrenal medulla functions similar to a postganglionic sympathetic nerve fiber
A = 1,2,3
B = 1,3
C = 2,4
D = 4 only
E = All of the choices are correct
F – None of the choices are correct

Back 82

E = All of the choices are correct

Front 83

Which of the following combinations is/are correct?
a. Radial muscle – mydriasis – alpha 1 receptor
b. Circular muscle – accommodation – M2 receptor
c. AV node – Increase conduction – M2 receptor
d. Detruser muscle – relaxation – beta 1 receptors
e. Liver – glycogenolysis – M3 receptors
f. Parasympathetic nerve terminal – Autoreceptor – M3

Back 83

a. Radial muscle – mydriasis – alpha 1 receptor

Front 84

Which of the following is/are true?
a. Sympathetic activation cause watery salivation
b. Parasympathetic activation significantly decreases conduction and contractility of the ventricles
c. Sympathetic activation contracts urinary and GI sphincters
d. Parasympathetic activation causes ejaculation in males
e. All of the choices are correct
f. None of the choices are correct

Back 84

c. Sympathetic activation contracts urinary and GI sphincters