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26 Cards in this Set
- Front
- Back
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What are the natural B-lactams?
What do they cover? |
Penicillin G & V
strep & pneumococcal |
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What are the penicillinase resistant B-lactams?
What do they cover? |
Methicillin
Dicloxacillin Nafcillin Oxacillin penicillinase producing staph |
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What are the broad spectrum B-lactams?
What are the combos of these with penillinase suicide inhibitors? What do they cover? |
Ampicillin
Amoxicillin Amoxicillin + Clavulanic acid Ampicillin + Sulbactam S. pyogenes, S. pneumoniae, H. influenzae |
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What are the anti-pseudomal B-lactams? and combos?
What do they cover? |
Piperacillin
Ticarcillin Piperacillin + Tazobactam Ticarcillin + Clavulanic acid P.aeruginosa, Proteus Enterobacter |
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What are the 1st generation cephalosporins?
What do they cover? |
Cephalexin
Cephadrine Cefadroxil Strep & S. aureus (more purely gram +) |
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What are the 2nd generation cephalosporins?
What do they cover? |
Cefprozil
Cefuroxime Cefmetazole Loracarbef E. coli, klebsiella, H. influenzae, moraxella catarrhalis |
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What are the 3rd generation cephalosporins?
What do they cover? |
Cefotazime
Cefpodoxime Cefibuten Cefdinir Cefditoren Ceftizoxime Ceftriaxone Cefoperasone, Ceftazidome Enterobacteriacai, p.aeruginosa, serratia, nisseria gonorrheae, pseudomonas |
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What are the 4th generation cephalosporins?
What are these resistant to? What do they cover? |
Cefepine
lactamase resistant same coverage as 3rd gen. |
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What are the 5th generation cephalosporins?
What do they cover? |
Ceftobiprole
MRSA, enterococcus, pseudomonas |
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T/F
B-lactams have limited lipid solubility and distributes well in tissues. |
true
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T/F
If you put B-lactams directly on the brain, you will have induced seizures. |
true
(tonic-clonic) |
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T/F
Cephalosporins have increasing Gram + activity with each generation. |
false
(increasing gram -) |
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T/F
The methothiotetrazole ring of cephalosporins interferes with vitamin D, causing bleeding. |
false
(vitamin K) |
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T/F
Penicillin G causes a disulfiram like reaction. |
False
(cephalosporins do...) |
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What are the Carbapenums?
What do they cover? |
Imipenum
Meropenum Ertapenum Dorapenum Gram +, Gram -, anaerobes, pseudomonas aeruginosa (dora does, erta does not) |
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Imipenum is compounded with __________ to inhibit the enzyme dehydropeptidase which is nephrotoxic.
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cilastatin
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Which carbapenum would you use to treat a community acquired infection?
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ertapenum
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Which carbapenum would you use to treat abdominal and compicated urinary infections?
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dorapenum
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Which carbapenums could you use to treat serious nosocomial infections?
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imipenem and meropenem
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Name the one monobactam available?
What does it treat? |
Aztreonam
Gram -, p. aeruginosa (NO GRAM +!!!) |
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Name the glycopeptide that treats MRSA, Gram +, penicillin-resistant enterococci and strep.
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Vancomycin
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Name the glycopeptide used as a single-dose therapy for uncomplicated UTI's due to E.coli or Enterococci faecalis.
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Fosfomycin
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What is the cyclic lipopeptide that binds to the cell membrane resulting in depolarization and loss of membrane potential and cell death?
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Daptomycin
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What does Daptomycin treat?
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broad spectrum gram +, vanc-resistant bacteria, staph and strep.
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What is the cyclic polypeptide that clocks the lipid carrier molecule to move peptidoglycan cell wall?
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bacitracin
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What kind of bacteria does Bacitracin kill?
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Gram +
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