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24 Cards in this Set

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  • Back
Penicillin G is considered a
Bacteriacidal/ Weakens Cell Wall
PCN G is effective against
Gram Pos and some Neg
PCN G treats
SYPHYLLIS
PCN G is eliminated in the
KIDNEYS
PCN G Immediate Allergic Reactions happens in
2 to 30 min
PCN G Accelerated AR happens in
1 to 72 hours
PCN G Late AR happens in
days to weeks
Anyphylaxis reaction to PCN G causes
laryngeal edema, bronchoconstriction, sever hypotension (GIVE EPINEPHRINE)
If mild allergy to PCN G give
CEPHALOSPORIN
If severe allergy to PCN G give
VANCOMYCIN or ERYTHROMYCIN
Most frequently prescribed in us
AMOXYCILLIN
Cephalosporins are what type of antibiotic
BEta- Lactum
Cephalosporins are considered
Bacteriacidal/ Weaken Cell Wall and Broad Spectrum
1st Generation Cephalosporins are destroyed by
Beta-Lactamases
2nd Generation Cephalosporins are
less sensitive to destruction
3rd and 4th Generation Cephalosporins are
highly resistant to Beta-Lactamases
Cephalosporins are given by IV or IM due to
poor GI absorption
Cephalosporins are excreted in the
KIDNEYS
Cephalosporins NOT excreted by kidneys are
CEFOPERAZINE and CEFTRIAXONE
(use in pt's w/ kidney dysfunctions)
Adverse Reaction to Cephalosporins are
Thrombophlebitis, Pain @ injection site, Nephrotoxicity
Drug interaction w/ Cephalosporins are
Probenicid, Alcohol, NSAIDS, Anticoagulants, Thrombolytics
A therapeutic use for 1st generation Cephalosporins is
Prophylaxis against infection in surgical patients
When would you give 1st generation Cephalosporins to a surgical PT
30-60 minutes Before surgery
1st generation Cephalosporins are
Cefadroxil, Cephazolin, Cefalexin, Cephadrine