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24 Cards in this Set
- Front
- Back
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Penicillin G is considered a
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Bacteriacidal/ Weakens Cell Wall
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PCN G is effective against
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Gram Pos and some Neg
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PCN G treats
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SYPHYLLIS
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PCN G is eliminated in the
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KIDNEYS
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PCN G Immediate Allergic Reactions happens in
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2 to 30 min
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PCN G Accelerated AR happens in
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1 to 72 hours
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PCN G Late AR happens in
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days to weeks
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Anyphylaxis reaction to PCN G causes
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laryngeal edema, bronchoconstriction, sever hypotension (GIVE EPINEPHRINE)
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If mild allergy to PCN G give
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CEPHALOSPORIN
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If severe allergy to PCN G give
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VANCOMYCIN or ERYTHROMYCIN
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Most frequently prescribed in us
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AMOXYCILLIN
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Cephalosporins are what type of antibiotic
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BEta- Lactum
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Cephalosporins are considered
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Bacteriacidal/ Weaken Cell Wall and Broad Spectrum
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1st Generation Cephalosporins are destroyed by
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Beta-Lactamases
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2nd Generation Cephalosporins are
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less sensitive to destruction
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3rd and 4th Generation Cephalosporins are
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highly resistant to Beta-Lactamases
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Cephalosporins are given by IV or IM due to
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poor GI absorption
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Cephalosporins are excreted in the
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KIDNEYS
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Cephalosporins NOT excreted by kidneys are
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CEFOPERAZINE and CEFTRIAXONE
(use in pt's w/ kidney dysfunctions) |
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Adverse Reaction to Cephalosporins are
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Thrombophlebitis, Pain @ injection site, Nephrotoxicity
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Drug interaction w/ Cephalosporins are
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Probenicid, Alcohol, NSAIDS, Anticoagulants, Thrombolytics
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A therapeutic use for 1st generation Cephalosporins is
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Prophylaxis against infection in surgical patients
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When would you give 1st generation Cephalosporins to a surgical PT
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30-60 minutes Before surgery
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1st generation Cephalosporins are
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Cefadroxil, Cephazolin, Cefalexin, Cephadrine
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