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10 Cards in this Set
- Front
- Back
Etiology of ADHD?
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Under activity of catecholaminergic system mediaded by dysregulation of DA and NE(Great DANE)
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Function of DA neurotransmission?
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Mediates arousal, involves attention, aids concentration
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Function of 5-HT neurotransmission?
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Dampens noise, enhances executive operations
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First line meds for ADHD?
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Amphetamine(dextroamphetamine) and methyphenidate
Affective in 70% of ADHD |
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Stimulant Efficacy?
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Ramp Effect depends on time to Tmax
concentration effect depends on peak concentration |
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Formulations of First line meds for ADHD?
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Imediate release
Intermediate Release(6-8hrs) Long acting release(10-12 hrs) |
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Side Effects of First line meds for ADHD?
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Decrease appatite, insomnia, tics, growth retardation
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Drud of Choice for Tics with ADHD?
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Atomoxetine. NE reuptake inhibitor, antidepressant
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Clonadine and Guanfacine?
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alpha agonist, antihypertension drugs, for hyperactivity,
DOC for children with tourette's or tic disorders |
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Modafanil?
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Wake producing used for narcolepsy
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