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37 Cards in this Set

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DOC for infections caused by gram + cocci
Used prophylactically (syphillis, rheumatic fever)
Not effective against PCNase producing organisms
PCN G
DOC for staph infections
narrow spectrum PCNase resistant PCN's
Most frequently prescribed abx in US
Amoxacillin
(broad spectrum PCN)
What should abx be given with to help reduce nausea?
Food
Can a patient with a PCN allergy be given Augmentin, Unasyn, or Timentin
NO
These contain PCN
What's the most common drug allergy?
PCN
Which group of abx should be used first?
Narrow spectrum (to help reduce resistance)
When giving Ampicillin and Genomycin at the same time, which should be given first?
Amp first (weakens the cell wall) allowing gent to enter
What's the major side effect of cephalo?
Bleeding
What's another major side effect of cephalo? (black box warning)
C. diff infection
When should vanc be used?
Rx severe infxns
MRSA
Ototoxicity
When should vanc be used?
Rx severe infxns
MRSA
Ototoxicity
When should vanc be used?
Severe Infxns
MRSA
Whats the most common side effects of vanc?
Ototoxicity
Thrombophlebitis
Redman's syndrome if given too fast
DOC for patients with true PCN allergy
Eryhromycin
What's contraindicated while taking erythromycin
Antihistamines
Could cause fatal dysrhythmias
What's are the major SE of tetracycline
Will stain teeth yellow (children)
Burn easily
What are the major SE of gent?
Nephrotoxicity
Ototoxicity
Describe the drug regimen for Non-resistant TB treatment
Induction phase (2 months) - 4 drugs
Continuation phase (4 months) - 2 drugs
Describe the drug regiment for resistant TB
(2 months) - 5 drugs
(1-2 years) 2-3 drugs
(compliance is very difficult)
What are the major drug interactions of Rifampin (Rifadin) (drug for TB)
Oral contraceptives
Warfarin
Drugs for HIV infxn
What are the major side effects of Ethambutol (Myambutol) TB treatment
Optic neuritis
Allergy
Hyperuricemia (leads to gout)
DOC for anthrax
Cipro
Major SE of cipro
GI
CNS - sz
Candida of mouth and vagina
Achilles tendon rupture
*C. diff infxn
What is Flagyl's main use
Infections caused by obligate anerobes
H. pylori
C. diff infxns
What should you NOT do with Flagyl
Put in the fridge
(loses its potency)
Why are systemic antifungals so toxic to the body
B/c the fungal membrane resembles the mammalian cell membrane
What's the major side effect of Amphotericin B (Fungizone) -- used to rx fungal infxn
Nephrotoxicity
Must be given over at least 6 hours
What are the major SE of protease inhibitors
Hyperglycemia/diabetes - known to precipitate diabetes
Reduced bone density
Hepatotoxicity
Antacids (Aluminum salts, what are the major side efffects and conta?
SE - constipation, hypercalcemia
Contra - osteomalacia (will pull more Ca out of bones)
Will also reduce absorption of warfarin, dig, Cipro
Give 2 hours before or after meals
(Antacid) Tums
Major SE
Constipation, hypercalcemia, metabolic alkalosis
What will MOM cause
diarrhea
What's the problem with histamine 2 receptor antagonists used as an antacid
Many drug interxns b/c in inhibits the P450 system
Tagment (worse)
How do prokinetic drugs work
Help increase motion through the gut
Increase gastric emptying time
What's the contra to prokinetic drugs
Epilepsy (precipitates sz)
Antisecretory agents (Prostoglandin analog)
What should be avoided
Antacids
When should a stimulant laxative NOT be used
When there is a possibility of mechanical obstruction