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15 Cards in this Set

  • Front
  • Back

Classes of drugs

N- narcotics


C- controlled


D- biologicals


Pr- prescription


R- restricted


OTC- over the counter

How to determine if a drug is prescription?

1. Pr symbol


2. Check prescription drug list


3. Any drug used off label

Drug label:

DIN


Trade, generic, chemical name


Manufacturer


Indicates class of drug


Pharmacology


Storage and handling


Indications


Precautions

Indications

Includes:


Condition


Specific patient type


Recommended dosage (mg/kg)


Route of administration


Frequency and duration or treatment

Examples of ELDU

Different spp


Different age group


Higher/lower dose


Longer/shorter duration


Combining w other drugs


Crushing tablets/ mixing in food


Splitting more than recommended

Compounded drugs

Drug that has been altered


Disadvantage: affects stability of the drug


May alter drug efficacy and se


Used when:


No other options exist

Hierarchy of prescription

1. Approved vet drug on label


2. Approved vet drug eldu


3. Approved human drug


4. Compounded drug


- a) from approved vet drug eldu


- b) from approved human drug

Dose

Total amount of drug given at any one time


Expressed as mg dosage

Dosage

Dosage regiment


Administering of specific amount of drug; number and frequency over time


Per kg dose (mg/kg)


Route


Frequency


Duration

Dosage forms

Tablet


Capsule


Sustained release


Suspension


Ointments


Paste


Injectables


Implants

Types of implants

Antibiotic impregnated beads implanted in joint


Hormone implant for calf

Drug toxicity

Acute adverse effects:


Often no further damage after drug removed


Effects on Cv/resp/muscles/GI/nervous/ endocrine/ repro


Chronic adverse effects:


Decreased repro, teratogenicity cancer


Long term liver

Lethal dose

Death


Median lethal dose (LD50)


Measure of toxicity


Kills 50% of animals that receive it

Dosing factors that maximize how long the drugs stay in therapeutic range:

Drug dosage


Route of admin


Giving a loading dose


- loading dose: first dose is larger


Loading interval: first few doses given more frequently


Dosage interval (frequency) maintenance

Maintenance dose

Repeated dose at set frequency to keep drug in therapeutic range