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17 Cards in this Set

  • Front
  • Back

Short acting beta-2-adrenoceptor agonists

Salbutamol


Terbutaline


Use 'as needed'

Long acting beta-2-adrenoceptor agonists

Salmeterol


Formoterol


Given twice daily



Non selective beta-adrenoceptor agonists

Isoprenaline


Adrenaline


Only used for Status Asthmaticus



Adverse effects of beta-2-adrenoceptor agonists

Tachycardia and palpitations


Pulmonary vasodilation

Xanthine Drugs

Theophylline


Aminophyline


Used in severe acute asthma

Adverse effects of Xanthine Drugs

Narrow therapeutic window


insomnia, nervousness, seizures


palpitations, tachycardia, dysrhythmia



Effects of carbamazepine on theophylline

Induce P450 enzymes therefore reduce action of theophylline

Effects of clarithromycin on theophylline

Inhibit P450 enzymes therefore potentiate action of theophylline

Muscarinic Receptor Antagonists

Ipratropium Bromide


Tiotropium

Action of ipratropium bromide

Inhibits mucus secretion / clearance of mucus

Ineffective against late phase asthma

Cysteinyl Leukotriene Antagonists

Zileuton


Montelukast

Action of zileuton

Directly inihibits 5-lipoxyoxygenase

Action of montelukast

Blocks CysLT1 receptors

Inhaled glucocorticoids

Beclometasone


Budesonide


Fluticasone

Side effects of glucocorticoids

Dysphonia


Oral pharyngeal candidiasis


Cough and throat irritation



Oral glucocorticoids

Prednisolone


Prednisone

Intravenous glucocorticoids

Hydrocortisone