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17 Cards in this Set
- Front
- Back
Short acting beta-2-adrenoceptor agonists |
Salbutamol Terbutaline Use 'as needed' |
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Long acting beta-2-adrenoceptor agonists |
Salmeterol Formoterol Given twice daily |
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Non selective beta-adrenoceptor agonists |
Isoprenaline Adrenaline Only used for Status Asthmaticus |
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Adverse effects of beta-2-adrenoceptor agonists |
Tachycardia and palpitations Pulmonary vasodilation |
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Xanthine Drugs |
Theophylline Aminophyline Used in severe acute asthma |
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Adverse effects of Xanthine Drugs |
Narrow therapeutic window insomnia, nervousness, seizures palpitations, tachycardia, dysrhythmia |
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Effects of carbamazepine on theophylline |
Induce P450 enzymes therefore reduce action of theophylline |
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Effects of clarithromycin on theophylline |
Inhibit P450 enzymes therefore potentiate action of theophylline |
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Muscarinic Receptor Antagonists |
Ipratropium Bromide Tiotropium |
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Action of ipratropium bromide |
Inhibits mucus secretion / clearance of mucus
Ineffective against late phase asthma |
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Cysteinyl Leukotriene Antagonists |
Zileuton Montelukast |
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Action of zileuton |
Directly inihibits 5-lipoxyoxygenase |
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Action of montelukast |
Blocks CysLT1 receptors |
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Inhaled glucocorticoids |
Beclometasone Budesonide Fluticasone |
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Side effects of glucocorticoids |
Dysphonia Oral pharyngeal candidiasis Cough and throat irritation |
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Oral glucocorticoids |
Prednisolone Prednisone |
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Intravenous glucocorticoids |
Hydrocortisone |