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5 Cards in this Set
- Front
- Back
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What is the function of warfarin and how is it metabolized?
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Long-term anti-coagulant orally-administered
Metabolized (phase I) by CYP2C9 |
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This NSAID is used to treat PDA
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Indomethacin
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What are the most common NS-COX inhibitors?
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Aspirin, ibuprofen, indomethacin, naproxen
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What is Reye's Syndrome?
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*Possible serious side effect of aspirin, seen in children with viral infection.
Symptoms include: acute encephalopathy and liver failure. With nausea, vomiting, changes in mental status and altered liver function. |
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By what pathways is acetominophen metabolized, and what is the frequency with which each pathway is pursued?
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*Glucuronidation (40-66%)
*Sulfation (20-40%) *Breakdown through toxic intermediate (<15%) |
