Reading...
Play button
Play button
Use LEFT and RIGHT arrow keys to navigate between flashcards;
Use UP and DOWN arrow keys to flip the card;
H to show hint;
A reads text to speech;
15 Cards in this Set
- Front
- Back
|
3 Major medications used for treating anxiety disorders are?
|
- Benzodiazepines
- Atypical anxiolytic / nonbarbiturate anxiolytics - Selective Serotonin Reuptake Inhibitors |
|
|
Sedative Hypnotic Anxiolytic - Benzodiazepine
Prototype Drug |
- Diazepam
|
|
|
Other Hypnotic Anxiolytic Benzodiazepines
|
- Alprazolam
- Lorazepam - Chloridiazepoxide - Clorazepate - Oxazepam - Clonazepam |
|
|
Diazepam Action
|
- enhances the inhibitory effects of GABA in the central nervous system. Relief from anxiety occurs rapidly following administration
|
|
|
Therapeutic uses for Diazepam
|
- Generalized Anxiety Disorder
- Panic Disorder - Seizure disorders - Insomnia - Muscle Spasm - Alcohol Withdrawl (acute symptoms - Induction of anesthesia |
|
|
Side Effects of Benzodiazepines
|
- CNS Depression (Sedation, light-headedness, ataxia, decreased cognitivefunction)
- Anterograde amnesia (trouble recalling events after dosing) - Acute Toxicity - Paradoxical response(Insomnia, excitation) - Withdrawal symptoms |
|
|
Contrindications of Benzodiazepines
|
- Pregnancy (causes;Cleft Lip and palates)
- Sleep-apnea - Respiratory depression - Liver disease - Renal disease |
|
|
Interactions of Benzodizepines
|
- other CNS depressants
(Alcohol, barbiturates, opioids) May cause respiratory depression |
|
|
Benzodiazepines should be tapered when discontinuing use.
True or False |
- True
|
|
|
Antidote for Diazepine overdose
|
- Flumazenil
|
|
|
Barbiturate Prototype Drug
|
- Phenobarbital
|
|
|
Barbiturates are used as?
|
- Anxiolytics-Hypnotics
|
|
|
Barbiturates Action
|
- Inhibits conduction in the ascending RAS; depresses the cerebral cortex; alters cerebellar function; depresses motor output; can produce excitation, sedation, hypnosis,anesthesia, and deep coma, and has anti-convulsant activity
|
|
|
Adverse Effects of Barbiturates
|
- Somnolence
- Agitation - Confusion - Hyerkinesias - Ataxia - Vertigo - CNS depression - Hallucinations - Bradycardia, Hypotension - Hypoventilation - Steven-Johnson Syndrome |
|
|
Contraindications of Barbiturates
|
- Allergy
- Previous addiction to barbs. or hallucinogenics - porphyria - Hepatic Impairment, Nephritis - Severe Respiratory Dysfunction - Pregnancy - Seizure disorders - Lactating women |
