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19 Cards in this Set
- Front
- Back
What are the 8 urinary tract drugs?
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* Ammonium chloride
* Atropine * Bethanechol * Dantrolene * Diazepam * Phenoxybenzamine * Phenylpropanolamine * Potassium citrate |
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What is the MOA of ammonium chloride?
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urinary acidifier-oxidized to urea in liver
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What is the MOA of Atropine?
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Muscarinic antagonist
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What is the MOA of Bethanecol?
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Direct Muscarinic Agonist
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What is the MOA of Dantrolene?
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Muscle relaxant
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MOA of Diazepam
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Muscle relaxant
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MOA of Phenoxybenzamine
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Alpha Adrenergic antogonist
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MOA of Phenylpropanolamine
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Adrenergic agonist
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MOA of potassium citrate
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Urinary alkalinizer – oxidized to bicarbonate in liver
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Result of Ammonium Chloride as a urinary tract drug
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Prevent/dissolve stones; enhance efficacy of antimicrobials when tx UTI
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Result of Atropine as a urinary tract drug
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Decrease detrussor mm. contraction; Urinary retention
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Result of Bethanchol as a urinary tract drug
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Increase detrussor mm. contraction
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Result of Dantrolene as a urinary tract drug
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Decrease external urethral sphincter tone
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Result of Diazepam as a urinary tract drug
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Decrease external urethral sphincter tone
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Result of Phenoxybenzamine as a urinary tract drug
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Decrease internal urethral sphincter tone
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Result of Phenylpropanolamine as a urinary tract drug
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Increase internal urethral sphincter tone
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Result of Potassium Citrate as a urinary tract drug
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Decreases calcium oxalate stone formation
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What receptors relax and contract the Detrussor mm.?
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Beta-2 relaxes; Muscarinic contracts
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What receptors innervate the internal and external urethral sphincters?
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* Internal: Alpha2
* External: Nicotinic |