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10 Cards in this Set

  • Front
  • Back
What antihypertensive medication is used in the prophylaxis of migraine headache
Give examples of medications in the “triptan” drug class
Sumatriptan; Almotriptan; Naratriptan; Rizatriptan; Zolmitriptan
What is the mechanism of action of sumatriptan
5-HT1D receptor agonist which causes vasoconstriction in cranial arteries
Why should sumatriptan be used with caution in a patient with angina
Can precipitate an anginal attack secondary to vasospasm of coronary arteries
How long after the first dose can a second dose of sumatriptan be given if migraine headache has not resolved
Dose may be repeated once after 2 hours
What is the mechanism of action of the ergot alkaloids
Causes vasoconstriction of cranial arteries less selectively than “triptans” by acting as an agonist of various 5-HT receptors throughout the body
Give an example of an ergot alkaloid
Ergotamine; Ergonovine
What are some common side effects of ergotamine
Nausea; Vomiting; Diarrhea; Chest pain; Toxic levels can cause gangrene
Why is ergotamine sometimes given with caffeine
Increased gut absorption
Are opioids analgesics usually effective against migraine headache