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19 Cards in this Set
- Front
- Back
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Which of the following actions is caused by pentobarbital?
A. Decreased affinity of the alpha subunit of GABA-A receptor for agonists. B. Decreased opening of GABA-controlled chloride ion channels. C. Increased activity of voltage-sensitive calcium channels. D. Decreased activity of NMDA receptors. E. None of the above |
D. Decreased activity of NMDA receptors.
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Which of the following agents will induce the activity of CYP3A4 when used daily for two weeks?
A. Ketamine B. Gamma-hydroxybutyrate C. Pentobarbital D. Oxycodone E. All of the above |
C. Pentobarbital
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Which of the following drugs develop a markedly narrower therapeutic index with repeated use?
A. Ramelteon B. Diazepam C. Oxycodone D. Secobarbital E. None of the above |
D. Secobarbital
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True/False
GHB increases the activity of GABA-A receptors |
False
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True/False
GHB decreases the activity of glutamate receptors |
True
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Which of the following actions is caused by pentobarbital?
a. Increased affinity of the alpha subunit of GABA-A receptor for agonists. b. Increased opening frequency of GABA-controlled chloride ion channels. c. Increased activity of voltage-sensitive calcium channels. d. Increased activity of NMDA receptors. e. All of the above |
a. Increased affinity of the alpha subunit of GABA-A receptor for agonists.
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Which of the following agents will induce the activity of CYP3A4 when used daily for two weeks?
a. Heroin b. Gamma-hydroxybutyrate c. Chlordiazepoxide d. Phenobarbital e. All of the above |
d. Phenobarbital
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Which of the following actions is caused by pentobarbital?
A. Increased affinity of the alpha subunit of GABA-A receptor for agonists. B. Increased opening of GABA-controlled chloride ion channels. C. Decreased activity of voltage-sensitive calcium channels. D. Decreased activity of AMPA receptors. E. All of the above |
E. All of the above
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Which of the following drugs directly stimulate dopamine neuronal firing in the mesolimbic pathway?
A. Varenicline B. Amphetamine C. Cocaine D. Heroin E. All of the above |
A. Varenicline
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Which of the following is true about fetal alcohol exposure?
A. Moderate alcohol ingestion during the third trimester (less than 2 glasses of wine/per day) is safe. B. FAS is characterized by abnormal facial characteristics and low IQ. C. If a pregnant woman consumes less than 2 glasses of wine per month, there is very little risk of occurrence of FAS. D. Consumption of over 3 drinks per day during pregnancy is necessary to significantly increase the incidence of ADHD in the developing child. E. All of the above |
B. FAS is characterized by abnormal facial characteristics and low IQ.
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Which of the following agents will be affected by induction of the activity of CYP3A4?
a. Propranololol b. Vitamin K c. Fluvoxamine d. Chlordiazepoxide e. All of the above |
e. All of the above
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hich of the following treatments is used to decrease protracted withdrawal symptoms in alcoholics?
a. Alprazolam b. Acamprosate c. Nalbuphine d. Disulfiram e. All of the above |
b. Acamprosate
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Which of the following is true about fetal alcohol exposure?
a. Alcohol ingestion during the first trimester (greater than 75 ml per day) is safer than alcohol ingestion during the last trimester. b. If a pregnant woman consumes three glasses of wine daily, there is a 33% risk of occurrence of FAS. c. FAS is characterized by high risk of Attention Deficit Disorder in childhood and alcoholism in the early teen years. d. If a pregnant woman consumes only one glass of wine occasionally, there is very little risk of occurrence of FAS. e. All the above |
b. If a pregnant woman consumes three glasses of wine daily, there is a 33% risk of occurrence of FAS.
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Which of the following agents will induce the activity of CYP3A4 when used daily for two weeks?
A. Secobarbital B. Gamma-hydroxybutyrate C. Ketamine D. Oxycodone E. All of the above |
A. Secobarbital
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Which of the following agents will be affected by induction of the activity of CYP3A4?
A. Cholesterol B. Vitamin D C. Pentobarbital D. Nefazodone E. All of the above |
E. All of the above
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Which of the following drugs can inhibit glutamate receptor activation?
A. Clonazepam B. Meperidine C. Varenicline D. Ketamine E. All of the above |
D. Ketamine
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Which of the following treatments for alcoholics may help decrease protracted withdrawal symptoms?
A. Odansetron B. Acamprosate C. Naltrexone D. Topiramate E. All of the above |
E. All of the above
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Which of the following drugs directly stimulate dopamine neuronal firing in the mesolimbic pathway? (ie. No interneuronal involvement)
A. Varenicline B. Heroin C. Cocaine D. Pentobarbital E. All of the above |
A. Varenicline
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Which of the following is NOT true about fetal alcohol exposure?
A. Alcohol ingestion during the first trimester (greater than 75 ml per day) increases the risk of FAS over 100 fold. B. FAS is characterized by abnormal facial characteristics and low IQ. C. If a pregnant woman consumes less than 25 ml of ethanol per month, there is very little risk of occurrence of FAS. D. Consumption of 25 ml of ethanol per month during pregnancy may significantly decrease the IQ, increase the incidence of ADHD and increase the incidence of alcohol problems in the developing child. E. All the above |
C. If a pregnant woman consumes less than 25 ml of ethanol per month, there is very little risk of occurrence of FAS.
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