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22 Cards in this Set

  • Front
  • Back

Pharmacology

Study of how X affects your body.


-PK how x passes through body


-PD affect of X on the body


We are talking about TE and side Effect

APD

Anti playlet drug aspirin


Prevents heart clotting but also


Makes wound healing longer

T or F

If x is produced by your body its not a drug


If its bottled it Is a drug .

Erythropotuen for

Erythropoesis

Brand innovative drug

First drug to be produced to perform certain function


Steps to making brand drugs ?

I-R&D


II preclinical :in vitro petri dish


And vivisection


III-clinical trails:


P1- volunteers Is it safe?/OD/TD/P2- patients does it work ,efficacy provide a hypothesis on how it does so


P3 -mass scale double blind experiment to prove hypothesis by proving X>placebo or previous treatment

Is a drug in released does it mean it will permebabtly stay on the market ?

NO!!! False if enough evidence prove it causes some severe ADR or SE it might be taken off

What advangtwge does the brand drug have?

It has monopoly over long period of time to make profits

Generics drugs

Can be made after the patent is over and formula released.

What are rules for generics ?

- same pharmaceutical formula


-same qualitative and quantitive properties


-same bioequivalence

Prescription vs non prescription drugs

Prescription can cause


Abuse misuse getting high


Dependence


And need MD Adm :BR ratio and effectiveness

How ADR are classified ?

-organ systemaffected


-frequency


&serious not serious


-expected vs non expected


- dose related

Can a drug with severe ADR still be given to patient .

Yes again depending on condition mention chemotherapy thingy

Who decides what drugs are in Lithuanian pharmacies ?

EMSA and EMA

Benefit vs risk ratio

What is it ?


Who decides it society vs individual

What is pharmacovigilance?why it is needed?

...

Tolerance vs FPE

Tolerance decreases drugs potency


While


FPE decreases its efficacy by decreasing its BA but not related to its potency

Why IV is given in veins

Veins are superficial and less pressure

How do we give X to unconscious of shock

IV or SC but not oral or sublinguL

What makes OP and rectal administration different.

They will undergo FPE before entering systematic circulation

If potency decrease s

Then the amount we need to have ED and TD also increasr

If someone is in shock or not nconcious we don't give it orally or siblingually

True