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23 Cards in this Set

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  • Back
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Types of cholinesterase

Types of muscuranic receptors

Types of nicotinic receptors

Cholinergic agonist s

Main activator and blocker of muscuranic and nicotinic receptors

M - act by muscuraine and blocked by atropine


N - act by nicotine and blocked by tubocuraine or hexamethonium

Action of ach on eye

Pilocarpine intro uses adverse effects

Bethanechol

.

Muscuraine

Mushroom poisoning

Physostigmine kinetic and uses

Kinetics - rapidly absorbed from git and parenteral routes.. Crosses cornea and bbb easily

Pyridostigmine

Similar to neostigmine but longer acting and less potent.. Thus more tolerant by mg patients and preferred more

Edrophonium uses

1 diagnosis of mg - ameliorative test


2 differentiate bw myastenia and cholinergic crisis


3 preferred in curare poisoning bcoz of its rapid onset of action

Drugs for treatment of glaucoma

Osmotic agents


Carbonic anhydrase inhibitor diuretics


B blocker a agonist


Anticholinesterases as miotics


Prostaglandins


Role of a agonist in glaucoma treatment

Apraclonidine and dipiverfrine

Compare physostigmine and neostigmine

As neostigmine has structure similar to ach, it directly acts at Nm receptors of NMJ and thus improve muscle power in patients of myastenia gravis

As neostigmine has structure similar to ach, it directly acts at Nm receptors of NMJ and thus improve muscle power in patients of myastenia gravis

Mechanism of action of anticholinesterases

Atropine pharmacological actions

Competitive antagonist of muscuranic receptors

Classify cholinergic drugs

Adrenergic receptors and their functions

Antimuscuranic drugs

Effects of atropine and ephedrine on eye

Why ipatropium bromide and tiotropium bromide is prefered over atropine in COPD and bronchial asthma

Use of scopolamoline

For motion sickness as by blocking cholinergic fibres it surpress vestibular disturbances