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13 Cards in this Set
- Front
- Back
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Prostaglandin effects on Cardiovascular system |
PGE2 & PGI2- vasodilators TXA2- vasoconstrictors |
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Prostaglandin effects on Platelets |
PGI2- antiaggregatory TXA2- proaggregatory |
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prostaglandins effects on uterine smooth muscle and parturition |
PGE and PGF2a- increase tone during pregnancy |
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prostaglandind effects on GI secretions |
cytoprotective ( PGE inhibits acid secretions and stimulates mucus secretions ) |
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prostaglandin effects on Kidney |
PGE2 and PGI2 - increase renal blood flow TXA2- decreases renal blood flow |
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prostaglandin effects on afferent neurons |
PGE2 and PGI2 potentiate pain and cause allodynia and hyperalgesia |
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Immune system |
PGs inc the production of interleukins, adhesion molecules, and TNF |
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Thrombosis |
balance b/w PGI2 / TXA2 |
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PARTURITION |
PGF2 / PGE2 |
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vascular tone |
PGI2 & PGE2 |
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regulation of bronchial smooth muscle tone |
PGF2a, TXA2, LT |
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renal blood flow and salt secretion regulation |
PGI2 & PGE2 |
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CANCER |
PGs and TXA2 promote cellular proliveration |
