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15 Cards in this Set
- Front
- Back
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Pharmacokinetics definition
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Study of the movement of drugs through the body.
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Process of drug pharmaco
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Absorbtion
Distribution Metabolism Elimination |
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Drug absorbtion
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75% of drugs are absorbed in the first 2-3 hours
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Blood brain barrier
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All psychotropic drugs pass through
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Cytochrome P450 (CYP)
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Enzymes in the GI tract that metabolize drugs
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Half Life
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When plasma levels of the drug is at 50%
6 half lives=elimination |
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TIme to reach steady state
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6 times the amount of time for elimination half life
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Simplest Atom
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Hydrogen
One proton, one electron |
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Molecules
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Stable configuration of atoms held together by bonds
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Types of Chemical bonds
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Covalent
Ionic Hydrogen |
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Covalent bonds
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Difficult to break
Share electrons |
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Ionic bonds
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Most are salts
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Factors influencing rate of reactions
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Temperature
Particle size concentration catalysts |
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Lipids
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No charge
fats and oils Large molecules |
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Phospholipids
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Cell membrane
Neutral in the middle, positive on the outside Small particles can get in |
