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26 Cards in this Set
- Front
- Back
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if the concentration of a nonelectrolyte is doubled, the osmotic pressure will be
a. reduced b. doubled c. increased by four times d. decreased by four times e. unaffected |
B
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2 pharmaceutical samples containing dextrose and sucrose, respectively, have the same osmotic pressure. Which of the following is true?
a. dextrose & sucrose are diff & cannot have the same osmotic pressure b. both samples have same molar conc. c. dextrose is a nonelectrolyte & sucrose is a strong electrolyte d. temp won't affect the osmotic pressure of samples e. samples won't have any vapor pressure |
B
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Which of the following is NOT TRUE for NaCl which dissociates completely in water?
a. there's an acidity/basicity constant for dissoc of NaCl b. there's no acidity/basicity constant for dissoc of NaCl c. ions will be formed upon dissociation d. electrolyte soln will be electrically conducting e. electrolyte soln will exhibit colligative properties |
A
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Drug delivery sys should possess all of the following characterisics EXCEPT
a. be able to deliver drugs to specific tissue-sites in body b. be able to reduce drug toxicity c. be able to contain a high concentration of drug d. be able to alter therapeutic indication (use) of drug e. be able to improve drug efficacy |
D
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A manufactured drug product should
I be appropriately labeled to promote FDA-approved use II. be stable as packaged III. exhibit max shelf-life a. I only b. II only c. I and II only d. II and III only e. I, II, and II |
E
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Excipients in a drug dosage form will influence all the following EXCEPT
a. drug product manufacturing b. disintegration of the dosage form c. therapeutic inidcation (use) of the drug d. dissolution of the dosage form e. drug absorption |
C
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During preformulation, physicochem characteristics of the drug & some extent those of excipients are also determined. These physicoche char include
I. stability of drug II. dissolution characteristics of drug III. surface area and packing/tap volume/density of drug a. I only b. II only c. I and II only d. II and III only e. I, II and III |
E
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The process of drug product devt is
I. expensive and time-consuming II. is considered to be a significant part of the field of pharmaceutics III initiated early-on, usually at the stage or preformulation/formulation a. I only b. III only c. I and II only d. II and III only e. I, II and III |
E
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A drug product should exhibit the following characteristics EXCEPT
a. it should be effective b. it should be novel c. it should be safe d. it should be stable e. it should be easy to administer |
B
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All of the following statements regarding micromeritics are correct, EXCEPT
a. it's the science of particles & includes char of particle properties b. it consists of determination of particle size, vol, & density c. particle char is not important during preformulation & formulation d. particle size affects dissolution rate & flow prop of powders e. particle shape can affect packing prop of the powder |
C
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Pharmaceutical soln can be the following types, EXCEPT
a. nasal sprays b. injectables c. suspension d. syrups e. opthalmic drops |
C
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pH values of hydroiodic acid syrup and naproxyn suspension are 1 and 2.2 respectively. Which of the following is true?
a. hydroiodic acid syrup is more acidic than naprxyn suspension b. hydroiodic acid syrup is less acidic than naprosyn suspension c. hydroiodic acid syrup is basic d. naprosyn suspension is basic e. both hydroiodic acid syrup and naprosyn suspension are basic |
A
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A aerosol dispenser uses two propellants, whose vapor pressures are 13 psi and 84 psi respectively. The two propellants can be mixed to obtain an appropriate final vapor pressure. Which of the following is true?
a. final vp will be in the range of 13psi and 84psi depending on the mole fraction of the 2 propellants b. final vp can't exceed 13 psi c. final vp can't be less than 84 psi d. final vp is difficult to estimate e. two propellants can't be mixed appropriately |
A
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pH of a soln is 5. If the soln is diluted 10-fold, the pH of the diluted soln will be
a. 4 b. 5 c. 5.5 d. 6 e. 7 |
D
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Two liquids of equal vp are mixed so that the mole fraction of each of the mixture is 0.5. The total vp of the mixture
a. will be doubled b. will be reduced by half c. will remain unchanged d. will drop to zero e. cannot be determined |
C
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Which one of the following mech is more frequently responsible for chem degradation
a. inversion b. racemization c. hydrolysis d. deamination e. decarboxylation |
C
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A first-order degration reaction is characterized by
I. dC/dt = -k II C=Co - kt III t1/2= -.693/k a. I only b. III only c. I and II only d. II and III only e. I, II, and III |
B
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Pharmaceutical salts can be used in all of the following ways, EXCEPT
a. to improve durg solubility b. to improve durg absorption c. to improve drug stability d. to facilitate manufacturing of the dosage form e. to alter therapeutic indication of the original drug |
E
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Prodrugs can be used in all the following ways, EXCEPT
a. to improve drug solubility and stability b. to achieve site-specific targeting of drugs c. to alter therapeutic indication of the original drug d. to facilitate formulation devt e. to encourage patient acceptance |
E
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Which one of the following statement concerning 1st-order degradation process is FALSE
a. its rate is dpt on the drug conc b. a plot of conc versus time yields a straight line c. it's t1/2 is indpt of conc d. a plot of the logarithm of conc versus time allows the rate constant to be determined e. its half-life is given by 0.693/k, where k is the 1st-order rate constant |
B
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A aerosol dispenser uses two propellants, whose vapor pressures are 13 psi and 84 psi respectively. The two propellants can be mixed to obtain an appropriate final vapor pressure. Which of the following is true?
a. final vp will be in the range of 13psi and 84psi depending on the mole fraction of the 2 propellants b. final vp can't exceed 13 psi c. final vp can't be less than 84 psi d. final vp is difficult to estimate e. two propellants can't be mixed appropriately |
A
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pH of a soln is 5. If the soln is diluted 10-fold, the pH of the diluted soln will be
a. 4 b. 5 c. 5.5 d. 6 e. 7 |
D
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Which one of the following mech is more frequently responsible for chem degradation
a. inversion b. racemization c. hydrolysis d. deamination e. decarboxylation |
C
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Complexation of a hydrophobic drug with cyclodextrin can result in all the following, EXCEPT
a. enhancement in drug solubility b. enhancement in drug stability c. enhancement in drug absorption d. precipitation of drug in the kidneyys e. enhancemnet in bioavailability of drug |
D
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The rate and/or mech of drug degradiation is dpt on
I. concentration II temp III pH a. I only b. II only c. I and II only d. II and III only e. I, II, III |
E
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Water-solubility of a drug is influenced by
I. pH II. functional side-chain of a drug III. molecular weight of a drug a. I only b. III only c. I and II only d. II and III only e. I, II, and III |
C
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