Reading...
Play button
Play button
Use LEFT and RIGHT arrow keys to navigate between flashcards;
Use UP and DOWN arrow keys to flip the card;
H to show hint;
A reads text to speech;
14 Cards in this Set
- Front
- Back
|
What is the key point for COPD and asthma treatment?
|
ALWAYS give a fast-acting agent with a short-acting agent and ALWAYS with a corticosteroid
|
|
|
what class is albuterol?
uses? |
prototype selective β2 agonists
short acting rescue inhaler for mild asthma levalbuterol and pirbuterol are similar to albuterol |
|
|
SE of albuterol?
|
tachycardia, tremor, dizziness for a brief period usually
|
|
|
what class is salmeterol?
use? |
LONG ACTING BETA-2 AGONIST
used for asthma |
|
|
why is salmeterol combined with corticosteroids?
|
to prevent down-regulation of the beta-2 receptors (prevents tolerance) and to also work on the inflammation
|
|
|
Theory behind the treatment of asthma?
|
need to open the airway and decrease the inflammation
|
|
|
what is ipratropium?
use? |
muscarinic antagonist used to take away muscarinic bronchoconstriction
used a lot in COPD and often combined with albuterol and sometimes used for acute asthma as well |
|
|
what is theophylline?
|
increases cAMP; similar to the beta-2, blocks adenosine receptors, ↓ the breakdown of cAMP
has central effects |
|
|
is theophylline used frequently?
|
NO because it has many SE, VERY NARROW THERAPEUTIC RANGE; a lot of drug interactions and can be very toxic in overdose
|
|
|
side effects of theophylline
|
causes you to be awake and alert
insomnia, anxiety, tachycardia, arrhythmias |
|
|
What are the SE for inhaled corticosteroids?
|
hoarseness and candiasis (thrush)
|
|
|
Actions of leukotriene inhibitors
|
"lukasts"
block the leukotriene receptors very effective to decreases inflammation, very few SE, very well tolerated |
|
|
what is zileuton?
|
leukotriene inhibitor that inhibits synthesis but nobody uses it
|
|
|
what is omalizumab?
|
antibody to IgE which prevents it from binding to mast cells
used to prevent allergic reactions in asthmatic patients |
