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36 Cards in this Set

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Rapid acting insulin


Lispro

Onset: 15-30 min


Peak: 0.5-2.5 hr


Duration: 3-6 hr

Short acting insulin


Regular (clear)

Onset: 0.5-1 hr


Peak: 1-5 hr


Duration: 6-10 hr

Intermediate insulin


NPH


(Cloudy)

Onset: 1-2 hr


Peak: 6-14 hr


Duration: 16-24 hr

Long acting insulin


Glargine

Onset: 70 min


Peak: 0


Duration: 18-24 hr

Hypoglycemia

When blood glucose is below 70 mg/dL

Hyperglycemia

When blood glucose is above normal range

Biguanides


Metformin

Reduces production of glucose in liver

Alpha-glucosidase inhibitors


Acarbose

Slows carb absorption and digestion

Alpha-glucosidase inhibitors


Acarbose

Take with first bite of food


Slows carb absorption and digestion

Thiazolidinediones


(Glitazones)


Pioglitazone


Rosiglitazone

Take once a day with or without food.


Increase cellular response to insulin by decreasing insulin resistance.

Sulfonylureas


Chlorpromazine


Glipizide

Insulin release from pancreas

Sulfonylureas


Chlorpromazine


Glipizide

Insulin release from pancreas

Meglitinides


(Non-sulfonylurea insulin secretagogues)


Repaglinide


Nateglinidesodium-glucose co-transporter 2

Insulin release from the pancreas

Dipeptidyl preptidase-4


(DPP-4)


Sitagliptin

Take with or without food.


Promotes release of insulin and decreases secretion of glucagon

Sodium-glucose co-transporter 2 inhibitors


(SGLT-2)


Canagliflozin


Dapagliflozin

Take before breakfast only.


Used in combo with Type 1 diabetes insulin


Limits rise of glucose postprandial

Glipizide and repaglinide

Take 30 minutes before mealtime.


Monitor for hypoglycemia.

Metformin

Take with breakfast and dinner.


GI effects: anorexia, nausea, diarrhea


Lactic acidosis: hyperventilation, myalgia, sluggishness,


Monitor for B12, folic acid deficiency, and lactic acidosis.

Amylin mimetics

Contraindicated for those with kidney failure or on dialysis.


Use cautiously with those with thyroid disease, osteoporosis, or alcohol disorder.

Incretin mimetics

Contraindicated for those with kidney failure, ulcerative colitis, Crohn’s, or Hx of pancreatitis.


Use cautiously on those with renal impairment, thyroid disease, or are elderly.


Avoid during pregnancy.

Antibiotics

Amoxicillin


Bismuth


Clarithromycin


Metronidazole (with food)


Tetracycline


Purpose: Eradication of H. Pylori bacteria

Histamine-2 receptor antagonists

Ranitidine


Cimetidine


Famotidine


Nizatidine (PO only)


Purpose: Block H2 receptors, which suppress secretion of gastric acid and lowers concentration of hydrogen ions in the stomach.

Proton pump inhibitors

Omeprazole


Pantoprazole


Lansoprazole


Dexlansoprazole


Rabeprazole


Esomeprazole


Purpose: Block basal and stimulated acid production, and reduce gastric acid secretion by irreversibly inhibiting the enzyme that produces gastric acid.

Probiotic

Increase normal flora in intestine and colon and reduce colonization of pathogenic bacteria.

Hiatal hernia

Proton pump inhibitors: blocks gastric acid to prevent reflux in hernia


Antacids: neutralize gastric acid to relieve manifestations.

Thyroid hormone

Levothyroxine


Liothyronine


Liotrix


Thyroid USP


Purpose: Increases metabolic rate, protein synthesis, cardiac output, renal perfusion, oxygen use, body temperature, blood volume, and growth process

Thionamides

Methimazole


Propylthiouracil (PTU)


Purpose: blocks thyroid hormones.

Radiopharmaceuticals

Radioactive iodine


Purpose: Absorbed by the thyroid and destroys some of the thyroid hormone-producing cells.

Mucosal protectant

Sucralfate


Purpose: The acidic environment of the stomach turns sucralfate into a barrier that adheres to ulcers.

Antacids

Aluminum hydroxide


Magnesium hydroxide


Calcium carbonate


Purpose: Neutralize or reduce the acidity of gastric acid.

Prostaglandin E analog

Misoprostol


Purpose: Decreases acid secretion, increases the secretion of bicarbonate and protective mucus, and promotes vasodilation to maintain submucosal blood flow.

Anti-emetics

Dexamethasone


Lorazepam


Aprepitant


Promethazine


Metoclopramide


Scopolamine


Hydroxyzine

Dexamethasone


Lorazepam


Aprepitant


Promethazine


Metoclopramide


Scopolamine


Hydroxyzine

Laxatives

Psyllium


Docusate sodium


Bisacodyl


Magnesium hydroxide


Senna


Lactulose

Anti-diarrheals

Diphenoxylate plus atropine


Loperamide


Paregoric

IBS-D

Irritable bowel syndrome with diarrhea


Alosetron


Purpose: Increases firmness in stool

IBS-C

Irritable bowel syndrome with constipation


Lubiprostone


Purpose: Promote intestinal motility

IBD

Inflammatory bowel disease


Sulfasalazine


Purpose: decreases inflammation with prostaglandin synthesis.