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37 Cards in this Set
- Front
- Back
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what type of chemical molecule is enflurane
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ether
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hyperventilation with enflurane can cause what to occur
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seizure acivity
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what range of PaCO2 with enflurane can cause seizure activity
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decreasing < 30 torr
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adminstration of what MAC with enflurane can cause sz activity
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> 2 MAC
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what is the trade name for enflurane
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ethrane
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does increasing MAC with enflurane lead to electrical silence
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NO
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is it recommended to give enflurane to a pt with a hx of seizures
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NO
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can enflurane be used to identify seizure foci
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YES
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where should PaCO2 levels be kept with enflurane and why
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within normal limits
-if not will cause seizure activity |
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how is autoregulation of cerebral blood flow affected with enflurane
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it is NOT completely intact
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compared to admin of halothane admin of enflurane has increases in BP/MAP that can cause what in regards to the brain
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smaller increses in brain protrusion
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what is the rate of CSF production with enflurane
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INCREASED
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what absorption of CSF with enflurane
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DECREASED
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enflurane may have what impact on ICP
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may increase it
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when is ICP increased with enflurane
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*with increase in CBF
*sz activity *with increased CSF production |
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when is ICP decreased with enflurane
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with a low MAP
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is enflurane good or bad for spontaneous ventilation and why
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it is the WORST agent for spontaneous ventilation b/c of its effect of PaCO2
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enflurane does what to myocardium
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depresses it to greater extent than halothane or isoflurane so there is a significant drop in CO
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metabolism of enflurane produces what
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inoganic fluoride ion
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even low fluoride ion concentrations have been associated with what
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25% decrease in max urine concentrating ability
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enflurane may temporily alter what function
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renal
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enflurane may be harmful to what type of patient
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pts with pre-existing renal dz
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what effect does enflurane have on skeletal muscle relaxation
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dose related skeletal relexation depression of N-M function
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what effect does enflurane have on muscle relaxants
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potentiates them
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enflurane provides what type of muscle relexation
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GOOD-may be adequate for abdominal sx
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use of a muscle relaxant with enflurane allows what to occur with dose of enflurane
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the dose to be decreased
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what is the greatest dose you would want to use with enflurane
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2 MAC
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why does enflurane have a lower incidence of biotransformation
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d/t to its low degree of biodegration
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how much oxidative metabolism does enflurane undergo
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2.5%
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the incidence of liver injury with and inhalation agent correlates with what
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oxidative metabolism
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what is the use for enflurane
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used in 3rd world countries
-cheap |
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what is a major problem with enflurane
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seizures
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what techniques should be avoided with enflurane
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*hyperventilation
*overpressuring |
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what type of patient should enflurane NOT be used in
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*renal dz
*history of sz disorder |
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enflurane can cause slight dysfunction in what organ
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liver
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enflurane has a cross sensitivity with what drug
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halothane
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what is enflurane particularly good at
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muscle relaxation
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