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39 Cards in this Set
- Front
- Back
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what labs should you do if you suspect DVT or PE?
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PTT
PT Platelets CBC D-Dimer |
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what is the first line Tx of Type II DM?
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Oral meds:
Glyburide 2.5mg BID or Metformin 500 mg PO BID |
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what is the best drug for high TGs?
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Niacin
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what is the best drug to lower LDL?
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Statins:
Crestor 5mg daily Lipitor 10mg daily |
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how do you dose adjust heparin?
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PTT; also used to monitor heparin
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name the 3 Bile Acid sequestrants
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Questran
Colestid Welchol |
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which drug causes flushing, hyperuricemia, and GI side effects?
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Niacin
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Do statins raise LDL?
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NO; they lower LDL and TGs
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which drug would you NOT want to give to a pt on warfarin(monitor INR), Beta blockers, or thiazides?
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Bile Acid Sequestrans - they reduce absorption of these drugs
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Name the 2 Fibric Acids
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GF
Gemfibrozil Fenifibrate |
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which drug can give you gall stones?
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Fibric acids
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which drug may increase TGs?
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Bile Acid Sequestrans
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T/F High TGs increase the risk of pancreatitis
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True; treat with Fibrates or Niacin to lower TGs
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what are the risk factors for hyperlipidemia?
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FLASH C
Family history Low HDL Age: men>45; women>55 Smoking HTN or HTN meds CHD |
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what's the first line Tx for Type II?
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Glyburide 2.5mg BID
Do A1c p 3 months and adjust if needed |
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why are first gen. sulfanylureas not used more?
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because they have active metabolites which cause side effects such as hypoglycemia
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what should your glucose be post prandial
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<126
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what is the risk of having high blood sugar in an ICU setting?
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> risk of acquiring an opportunistic infection
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what is an alternative Tx for 70/30 insulin?
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Lantus 10 U/day, add Lispro(Rapid)
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What is the insulin dose for ketosis?
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Start Insulin Drip (regular) mixed in a 1:1 ratio (100 U in 100cc saline)
After insulin drip: 1.0 IU/Kg/day |
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start a 90kg pt on insulin
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dose is 0.5 IU/kg/day:
45 U/day Split into 70/30 Use 70% NPH; 30% Regular |
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a patient comes in with a stroke, what do you do?
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Do CT first
Start heparin if ischemic |
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what is the first line Tx of an Ischemic stroke?
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Thrombolytic:
TPA- use within 3 hrs of Sx Monitor PTT, INR, CBC because a bleed can occur |
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If you have a Hemorrhagic stroke, what do you do?
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Contact neurosurgeon
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Give TPA to a 60Kg Ischemic stroke patient
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Dose is 0.9mg/kg/IV
.9x60= 54mg Give 10% bolus= 5.4mg 48.6mg IV over 1 hr |
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who should not get TPA?
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Any pt at risk of bleed, h/o recent seizure or brain neoplasm
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what antiplatelet therapy can you give for ischemic stroke?
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ASA
Aggrenox Ticlodipine Plavix Warfarin |
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your pt has TGs of 225, which cholesterol drug would you give and which ones would you avoid?
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Avoid:
Bile Acids - they may > TGs Give Niacin 2gm |
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what is your LDL goal for a pt with no CHD and has more than 2 risk factors?
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LDL <130
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your patient has liver disease and you want to reduce his LDL, what drug do you choose?
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Bile Acid sequestrants:
Questran 5gm daily |
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Which cholesterol drugs are CI in liver disease?
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Statins-absolute
Niacin Fibric Acids |
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what do you monitor with statins?
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CPK
LFT Lipid levels |
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what is the best drug to raise HDL?
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Niacin >15-35%
2gm daily |
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Your pt is hypoglycemic and on AGIs, what do you do?
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Give glucose, NOT sucrose, because the AGIs slow breakdown and absorption of sucrose in the intestines
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when should your pt take their AGIs?
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Before every meal so the drug is present to inhibit enzyme activity
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Your pt has CHF and has Type II, what drug should you avoid?
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TZD, becase it causes edema and as a result a dilution anemia.
Also avoid Metformin |
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this drug enhances insulin sensitivity in hepatic and peripheral muscle tissues
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Metformin
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What are the two diabetic drugs that should be given with meals?
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AGIs
Meglitinides |
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In which type of diabetes does DKA most often occur?
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Type I
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