Pharm Test 6D - Glucocorticoids (Steroids) And Ra

Front 1

glucocorticoids used in low doses for

Back 1

endocrine disorders

Front 2

glucocorticoids used in high doses for (6)

Back 2

asthma, cancer, allergies, arthritis, transplant, lupus

Front 3

allograft means

Back 3

transplant

Front 4

glucocorticoid action: (4)

Back 4

suppress:

inflammation (prostaglandins, histamine, leuko)

phagocytes

lysosomal enzymes

lymphocytes

Front 5

adverse of glucocorticoids (7)

Back 5

ulcer, glucose

glaucoma, osteoporosis

infection, potassium loss,

sodium retention

Front 6

glucocorticoids lower _______ electrolyte among others

Back 6

potassium

Front 7

for patients with adrenal insufficiency___________

Back 7

give extra glucocorticoid steroids during physiologic stressors like surgery

Front 8

administer glucocorticoid steroids ___________

Back 8

before 9am

Front 9

name two glucocorticoid steroids:

Back 9

cortisone, prednisone

Front 10

glucocorticoids and vaccines?

Back 10

no live flue vaccines

Front 11

dose schedule for glucocorticoids

Back 11

every other day before 9am

Front 12

cushing syndrome

Back 12

moon face

Front 13

potassium loss can interact with (2)

Back 13

diuretics and digoxin (increase levels)

Front 14

symptoms of rheumatoid arthritis (3)

Back 14

inflammation, cornea, vasculitis

Front 15

goals of RA therapy (4)

Back 15

reduce symptoms

joint and range of motion

minimize systemic

delay disease progress

Front 16

3 types of drugs to treat RA

Back 16

NSAIDS, glucocorticoid steroids,

disease modifying antirheumatic drugs (DMARDS)

Front 17

two types of DMARDS

Back 17

nonbiologic traditional

biologic DNA recombined

Front 18

NSAID relief RA symptoms but...(2)

Back 18

don't prevent injury

don't delay disease progress

Front 19

glucocorticoids.... (2)

Back 19

act quickly

might delay disease

Front 20

DMARDS take ________ to see benefits

Back 20

3 months

Front 21

safest of three RA drug groups

Back 21

NSAIDS

Front 22

dose of NSAIDS for RA are _________ compared to NSAIDs dose for pain and fever

Back 22

much higher

Front 23

this group of meds is very toxic and only used for short period for RA treatment

Back 23

glucocorticoids

Front 24

DMARD of first choice

Back 24

methotrexate

Front 25

TNF means

Back 25

tumor necrosing factor

(body's normal autoimmune response to kill tumors but can attack self with autoimmune diseases like RA)

Front 26

__________, a biologic DMARD, neutralized TNF, suppressing autoimmune attack on joints

Back 26

Etanercept

Front 27

adverse of Etanercept and other TNF antagonist (biologic DMARDs)

Back 27

compromise the whole immune system making you susceptible to all sorts of infections

TB, HBV

Front 28

HBV means?

Back 28

hepatitis B

Front 29

TNF antagonists route

Back 29

sub Q

Front 30

name one TNF

Back 30

etanercept

Front 31

to reduc symptoms of TNF IV reaction use ____________ beforhand (3)

Back 31

antihistamine, acetaminophen, glucocortioid

Front 32

one symptom of RA drug IV reaction

Back 32

hypotension

Front 33

other RA drugs workd by inhibtin (3)

Back 33

T cells, B cell, interluikins

Front 34

reaction to RA medication might include _____________(1) due to immunosuppression

Back 34

fever

Front 35

entanercept requires which lab test first?

Back 35

tb test

Front 36

side effect of RA drug hydroxychloroquine

Back 36

retinal

Front 37

leflunomide (arava) - 3 side effects

Back 37

tb, pregnancy, diarrhea