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23 Cards in this Set
- Front
- Back
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how does acetaminophen cause hepatic cell necrosis?
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converted @ HIGH DOSES to reactive metabolite, overloads pathways
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maximum recommended dose of acetaminophen
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4000 mg
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acetaminophen can be given to anti-coagulant patient w/ no effect
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true
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acetaminophen is a....
anti inflammatory antipyretic analgesic |
andipyretic
analgesic |
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acetaminophen is 2 things...
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andipyretic
analgesic |
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acetaminophen is less than 1 hr? T or F
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T
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acetaminophen onset is....
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less than 1 hjr
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Vicoden =
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hydrocodone 7.5 mg
acetaminophen 750 mg |
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10% of population is allergic to aspirin
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FALSE
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Effects of aspirin
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analgesic
antipyretic antiinflammatory antiplatelet |
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primary route of metabolism of aspirin
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cholinesterase hydrolysis (plasma)
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antiplatelet effect of aspririn due to inhibition of
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TXA2
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TXA2 inhibited by, which causes...
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aspirin,
anti-platelet |
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aspirin
prevent reye's? manage Rh arthritis? manage gout? tx of fever? prevent MI? |
all but reyes
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can you take aspirin and ibuprofen?
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no
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what % allergic to aspirin?
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.2%
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aspirin can be taken for...
heart attack MI angina |
NOT angina
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2 heart conditiosn to take aspirin for?
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MI
heat tattack |
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aspirin causes GI problems and also...
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thrombocytopenia
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onset of actions for aspirin?
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1-2 hrs
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how does aspirin reduce fever (antipyretic)
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reduce PGE2 reduction
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reducing PGE2. what does it do? who does it?
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aspirin,
stops fever |
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give aspirin to chicken pox kids?
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NO
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