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47 Cards in this Set
- Front
- Back
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Amoxapine |
Antidepressant, 2nd line 2nd TCA: blocks NE transporter |
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Imipramine |
Antidepressant, 2nd line 3rd TCA: blocks NE and SE transporter |
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Fluoxetine |
Antidepressant, 1st line SSRI: blocks SE reuptake transporter |
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Duloxetine |
Antidepressant, 1st line SNRI: blocks SE and NE reuptake transporter |
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Phenelzine |
Antidepressant, 3rd line MAOI-A&B, Nonselective |
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Moclobemide |
Antidepressant, 3rd line MAOI-A, Reversible |
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Ketamine |
Antidepressant, last resort NMDA Receptor Inhibitor, noncompetitive |
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Triazolam |
Anxiety Benzodiazepine: increases GABA short-term, Insomnia (TAD) |
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Alprazolam |
Anxiety Benzodiazepine: increases GABA intermediate-acting, anxiety (TAD) |
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Diazepam |
Anxiety & Alcohol detox Benzodiazepine: increases GABA long-term, alcohol detoxification (TAD) |
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Flumenazil |
Anxiety Benzodiazepine receptor antagonist (different site) |
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Phenobarbital |
Anxiety Barbiturate, increase GABA activity long-acting: seizures |
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Pentobarbital |
Anxiety Barbiturate, increase GABA activity short-acting: general anesthetic |
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Clonidine |
Anxiety & Opiod detox & Hypertension a2 autoreceptor agonist: decrease NE release Hypertension-sympatholytic agent, indirect |
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Propanolol |
Anxiety & Hypertension B receptor antagonist: prevent NE effects Hypertension- sympatholytic, direct & non-selective |
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Carbamezapine |
Seizure & Alcohol detox Prolongs inactive state of Na-K channels Partial seizures |
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Valproate |
Seizure prolongs inactive state, inhibits t-type Ca channels, & increases GABA signaling Partial, General TC, Absence (w/ others) |
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Topiramate |
Seizure Decreases AMPA General TC |
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Ethosuximide |
Seizure Inhibits t-type Ca channels Absence seizures |
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Clonazepam |
Seizure Benzodiazepine: increase GABA activity (additional MOA) |
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Felbamate |
Seizure Decreases NMDA activity (additional MOA) |
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Ezogabine |
Seizure Opens K channel (additional MOA) |
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Levodopa |
Parkinsons Dopamine precursor |
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Carbidopa |
Parkinsons Dopamine Decarboxylase inhibitor (peripheral) Admin w/ L-DOPA |
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Entacapone |
Parkinsons COMT Inhibitor Admin w/ L-DOPA |
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Selegiline |
Parkinsons MAO-B Inhibitor: Decrease DA metabolism No decrease in ROS |
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Rasagline |
Parkinsons MAO-B Inhibitor: Decrease DA metabolism Potential decrease in ROS |
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Ropinirole |
Parkinsons DA Receptor agonist: D2 useful in early stages |
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Haloperidol |
Schizophrenia 1st generation, typical antipscyhotic Block DA D2 receptors |
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Clozapine |
Schizophrenia Original, atypical antipsychotic Block DA D2 & SE receptors Effects postivie & neg (& some cog) |
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Olanzapine |
Schizophrenia 2nd generation, atypical antipsychotic Block DA D2 & SE receptors |
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Quetiapine |
Schizophrenia 2nd generation, atypical antipsychotic Block DA D2 & SE receptors |
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Nicotine Replacement |
Tobacco detox abst rate 10-17% |
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Varenicline |
Tobacco detox Nicotinic receptor parial agonist abst rate 25% |
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Bupropion |
Tobacco detox Inhibits MA uptake, stabliza DA levels abst rate 22% |
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Methadone |
Opiod detox U opioid receptor full agonist more stable, long half-life |
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Naltrexone/Naloxone |
Opioid detox & Alcohol detox U opioid receptor antagonist |
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Buprenorphine |
Opioid detox Partial U opioid agonist |
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Suboxone |
Opioid detox Combo of buprenorphine & naloxone Sublinugal- 50% buprenorphine IV-Withdrawals |
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Disulfiram |
Alcohol detox Antabuse, blocks alcohol dehydrogenase- bad withdrawals with relapse |
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Acamprosate |
Alcohol detox Anticraving Blocks Glu receptors between PFC-NAc |
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Chlorthalidone |
Hypertension Diuretic Thiazide, blocks Na reabsorption in distal tubule |
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Furosemide |
Hypertension Diuretic Loop diuretic, blocks Na reabsorption in loop of Henle |
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Spironolactone |
Hypertension Diuretic Potassium-sparing, blocks Na-K exchange in collecting duct |
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Reserpine |
Hypertension Sympatholytic, indirect Release inhibitor: Causes NE leakage from vesicles intracellularly |
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Atenolol |
Hypertension Sympatholytic, direct B-Blocker, cardioselective-only B1 Safe for asthmatics and diabetics |
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Prazosin |
Hypertension Sympatholytic, direct A1 receptor antagonist: block vasoconstriction |
