**pharm Test 2 - Review

Front 1

isoflurophate, echothiophate are both

Back 1

irreversible ACHEIs

Front 2

carbachol and bethanechol, in having a beta methyl group are special because they

Back 2

are completely resistnant to hydrolysis via ACHE

Front 3

How is pralidoxime used as an antidoe?

Back 3

it removes the Phosphate from ACHE, allowing it to work, stopping "aging" process

Front 4

if echothophate or isofluorphate are used, what must also be used in large amounts if necessary?

Back 4

atropine

Front 5

what drug treats seasickness?

Back 5

scopolamine

Front 6

To test for MG, give _____1st. if you get improvement, rx ______. if deteriorate, then try_____. If get good result, then increase ______. if deteriorate again, give _____

Back 6

endrophonium
pyridostigmine
endrophonium
pyridostigmine
less pyridostigmine

Front 7

If given too much echothophate/isofulorate, give ____. if given too much of that, give _____

Back 7

atropine
physostigmine

Front 8

2 drugs from POSTERIOR pituitary

Back 8

vasopressin, oxytocin

Front 9

this drug works in that it....
stops withdawal symptoms
eliminates craving for opiate
blocks opiate induced euphoria
correc neurochem abnormalities in brain

Back 9

Methadone

Front 10

what are the 3 benefits to using methadone to treat opiate addiction?

Back 10

cost
effective
reduce risk of HIV/HEP C

Front 11

methadone has several controversies, such as

Back 11

dose
length of stay
detox
stigma
pregnancy

Front 12

Methadone maintenance lies between what 2 parameters

Back 12

under tolerance
above abstinence

Front 13

epinephrine/NE come from what source?

Back 13

Tyrosine form the diet

Front 14

What drug is the alpha AND beta agonist, is the sole drug of "mixed action" quality, causing NE release from SNS.

Back 14

ephedrine, pseudoephedrine

Front 15

albuterol, a (receptor) ___(agonist/antagonist)____ works in that it relieves....

Back 15

b2 agonist
bronchoconstriction

Front 16

Dobutamine is a (receptor) (ag or antag) an its ____effect is greater than its _____effect.

Back 16

beta 1 agonist
inotropic
chronotrpoic

Front 17

what beta 2 selective agonist has the longest effect?

Back 17

salmeterol and fromoterol

Front 18

____is a a2 receptor agonist , which therefore decreases_____.

Back 18

Clonidine
NE release

Front 19

Clonidine is a _______. and acts to decrease _____>

Back 19

a2 agonist
NE release

Front 20

dextroamphetamine is used to treat

Back 20

ADHD

Front 21

What drug is the MOST selective beta 1 blocker, effects due to NO path

Back 21

nebivolol

Front 22

which drus is the ULTRA SHORT acting beta 1 blocker?

Back 22

esmolol

Front 23

what drug prevents REUPTAKE of NE?

Back 23

resuprine

Front 24

Leukemia/cancers can be first diagnosed when cell count is above___, weighting

Back 24

10^9 cells
1g

Front 25

folic acid antagonist antimetabolite drug is

Back 25

methotrexate

Front 26

pyrimidine analog antimetabolite drug is

Back 26

5-fluorouracil

Front 27

What is the MOST IMPORTANT and widely used anticancer drug that intercalates DNA?

Back 27

doxorubicin

Front 28

Doxodubicin is a drug that acts by _____and has an infamous nature in that it is

Back 28

intercalates DNA
most widely used anti-cancer drug

Front 29

bleomycin is an anticancer drug, to tx ___cancer it is a mix of ___chelating glycopeptides

Back 29

testicle
copper

Front 30

Prednisone's effects are antiinflammatory, but it has a side effect of

Back 30

bone loss

Front 31

____is a drug with a side effect of bone loss but has anti-inflammatory properties

Back 31

prednisone

Front 32

diethylstilbesterol (DES)

Back 32

chemicocarcinogens pass from one gen to another

Front 33

A drug that ends in -mab is what?

Back 33

monoclonal antibody

Front 34

buserelin is a hormone drug used for ______

Back 34

advanced prostate cancer and endometriosis

Front 35

drug used for advanced prostate cancer and endometeriosis (begins w/ B)

Back 35

buserelin

Front 36

drug used for advanced prostate cancer and endometeriosis (begins w/ L)

Back 36

leuprolide

Front 37

cisplatin is an anticancer drug using a ____(element)___complex

Back 37

platinum

Front 38

premarine is a source of ____from _____

Back 38

estrogen
equine

Front 39

a1 mechanism of transduction?

Back 39

IP3/DAG

Front 40

a2 mechanism of transduction?

Back 40

cAMP

Front 41

b1 mechanism of transduction

Back 41

cAMP

Front 42

b2 mechanism of transduction

Back 42

cAMP

Front 43

b3 mechanism of transduction

Back 43

cAMP

Front 44

what drug is from equine source?

Back 44

premarin

Front 45

which activates estrogen receptors?

Back 45

raloxifene

Front 46

testosterone is used for ana/cata effects?

Back 46

ana